PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 30147.m014015
Common NameLOC8258125, RCOM_1512740
Organism
Ricinus communis
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; Acalyphoideae; Acalypheae; Ricinus
Family E2F/DP
Protein Properties Length: 389aa    MW: 43245.5 Da    PI: 8.3424
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
30147.m014015genomeJCVIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP75.36.3e-242186171
        E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                   rk+ksL+ll+++fl+l+ k   +++ l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++wkg
  30147.m014015 21 RKQKSLGLLCTNFLSLYDKDGIEVIGLDDAASKL---GV--ERRRIYDIVNVLESVGVLSRKAKNKYTWKG 86
                   79*****************999************...**..****************************98 PP
2E2F_TDP794.4e-25160240171
        E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                    rkeksL+lltq+f+kl+ +s+++ ++l+e+ak L+ +      +++k+RR+YDi+NVL++l+liek     ++k+++rw g
  30147.m014015 160 RKEKSLGLLTQNFVKLFLCSKADLISLDEAAKLLLGDahnssIMRTKVRRLYDIANVLSSLKLIEKthtaeSRKPAFRWLG 240
                    79***************************************999**********************9999999******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.108.3E-271787IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467855.45E-162084IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.3E-282186IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023192.4E-202286IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.101.3E-23158241IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013722.8E-33160240IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023198.2E-20161240IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.5E-13162241IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 389 aa     Download sequence    Send to blast
MPLSSNEAPT ESSCRHHTYS RKQKSLGLLC TNFLSLYDKD GIEVIGLDDA ASKLGVERRR  60
IYDIVNVLES VGVLSRKAKN KYTWKGFGAI PKALQELKEE GLKENLSSFD NKQPSNNCEK  120
ASDDENDDED DCDSNPNTGS QNSIPSGISK STAASRFDNR KEKSLGLLTQ NFVKLFLCSK  180
ADLISLDEAA KLLLGDAHNS SIMRTKVRRL YDIANVLSSL KLIEKTHTAE SRKPAFRWLG  240
LRVKSESGSA DALAESRKRR FGVDVTNICI KRNKVDGSSA DADKSESLKM HGQIKVEDVL  300
TIADRSSVGQ DAQQGSKSYQ FGPFAPVTVA KLGDSENKQT PTHDWESLAA TYRPQYHNQA  360
LRELFAHYME AWKSWYTEVA GKKPIEQIS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-41202323228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap30147.m014015
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002511465.10.0E2F transcription factor-like E2FE
SwissprotQ8LSZ41e-132E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLB9R8Z00.0B9R8Z0_RICCO; E2F, putative
STRINGXP_002511465.10.0(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF36683366
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-135DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]