PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462907195
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family WRKY
Protein Properties Length: 476aa    MW: 53139.4 Da    PI: 9.326
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462907195genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY85.25.9e-27101162159
                ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                +dDg++WrKYGqK++ g+++pr+YYrCt++   gC+++k+++rs+edp+++++tY g+H+++
  462907195 101 VDDGHSWRKYGQKVILGAKHPRAYYRCTHRhshGCTATKQLQRSDEDPTIFDVTYYGTHTCN 162
                59***************************99999**************************97 PP
2WRKY85.25.9e-27308369159
                ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
       WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                +dDg++WrKYGqK++ g+++pr+YYrCt++   gC+++k+++rs+edp+++++tY g+H+++
  462907195 308 VDDGHSWRKYGQKVILGAKHPRAYYRCTHRhshGCTATKQLQRSDEDPTIFDVTYYGTHTCN 369
                59***************************99999**************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.805.3E-2789163IPR003657WRKY domain
PROSITE profilePS5081121.83896164IPR003657WRKY domain
SuperFamilySSF1182902.35E-2598163IPR003657WRKY domain
SMARTSM007741.6E-38101163IPR003657WRKY domain
PfamPF031061.3E-25102161IPR003657WRKY domain
Gene3DG3DSA:2.20.25.805.3E-27296370IPR003657WRKY domain
PROSITE profilePS5081121.838303371IPR003657WRKY domain
SuperFamilySSF1182902.35E-25305370IPR003657WRKY domain
SMARTSM007741.6E-38308370IPR003657WRKY domain
PfamPF031061.3E-25309368IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010200Biological Processresponse to chitin
GO:0048527Biological Processlateral root development
GO:0005730Cellular Componentnucleolus
GO:0000987Molecular Functioncore promoter proximal region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 476 aa     Download sequence    Send to blast
MESVDGNNGD SRLVVTQLNH IKDLVMQLET HLGASQDICK HLASQIFTIT ERSIVLITST  60
NLDIGRKHKN VQFKTTQKRT MVENRRHQVR VNSVAAGAIP VDDGHSWRKY GQKVILGAKH  120
PRAYYRCTHR HSHGCTATKQ LQRSDEDPTI FDVTYYGTHT CNRTTDTAAG QAKQTPEHTQ  180
PRRAQPPAHA SERNLMISWP SKSSDHWGVS PATSDSNHVL SLPPFEAAAG DVMQLETHLG  240
ASQDICKHLA SQIFTITERS IVLITSTNLD IGRKHKNVQF KTTQKRTMVE NRRHQVRVNS  300
VAAGAIPVDD GHSWRKYGQK VILGAKHPRA YYRCTHRHSH GCTATKQLQR SDEDPTIFDV  360
TYYGTHTCNR TTDTAAGQAK QTPEHTQPRR AQPPAHASER NLMISWPSKS SDHWGVSPAT  420
SDSNHVLSLP PFEAAAGDAR WPEQSEHQEV VTASAPASTA EIIKNFVDID FSSFFM
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A6e-21101368868OsWRKY45
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). Positive regulator of EDS1-dependent defense against E.amylovora (PubMed:22316300). Together with WRKY70 and WRKY53, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847). {ECO:0000250, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321, ECO:0000269|PubMed:28576847}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00112ampDAPTransfer from AT2G46400Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap462907195
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by drought, salt and hydrogen peroxide treatments (PubMed:24773321). Induced by salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Up-regulated by E.amylovora (PubMed:22316300). Triggered by P.syringae (PubMed:22325892). {ECO:0000269|PubMed:22268143, ECO:0000269|PubMed:22316300, ECO:0000269|PubMed:22325892, ECO:0000269|PubMed:24773321}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK3770661e-46AK377066.1 Hordeum vulgare subsp. vulgare mRNA for predicted protein, partial cds, clone: NIASHv3147D20.
GenBankKU0586251e-46KU058625.1 UNVERIFIED: Panicum miliaceum WRKY10-like gene, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025800891.13e-72probable WRKY transcription factor 30
SwissprotQ9SKD96e-30WRK46_ARATH; Probable WRKY transcription factor 46
TrEMBLA0A2S3GYW58e-71A0A2S3GYW5_9POAL; Uncharacterized protein
STRINGSb02g022280.12e-71(Sorghum bicolor)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP108638131
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G46400.12e-32WRKY DNA-binding protein 46
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Sheikh AH, et al.
    Regulation of WRKY46 Transcription Factor Function by Mitogen-Activated Protein Kinases in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 61
    [PMID:26870073]
  3. Yan JY, et al.
    A WRKY Transcription Factor Regulates Fe Translocation under Fe Deficiency.
    Plant Physiol., 2016. 171(3): p. 2017-27
    [PMID:27208259]
  4. Chen J, et al.
    Arabidopsis WRKY46, WRKY54, and WRKY70 Transcription Factors Are Involved in Brassinosteroid-Regulated Plant Growth and Drought Responses.
    Plant Cell, 2017. 29(6): p. 1425-1439
    [PMID:28576847]
  5. Ma J, et al.
    Overexpression of TaWRKY146 Increases Drought Tolerance through Inducing Stomatal Closure in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 2036
    [PMID:29225611]