PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 462962084
Organism
Eragrostis tef
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Poaceae; PACMAD clade; Chloridoideae; Eragrostideae; Eragrostidinae; Eragrostis
Family TALE
Protein Properties Length: 305aa    MW: 34607.9 Da    PI: 6.8669
Description TALE family protein
Gene Model
Gene Model ID Type Source Coding Sequence
462962084genomeTefView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Homeobox26.41.2e-082332682055
                HHSSS--HHHHHHHHHHCTS-HHHHHHHHHHHHHHH CS
   Homeobox  20 eknrypsaeereeLAkklgLterqVkvWFqNrRake 55 
                +k +yps++++  LA+++gL+ +q+ +WF N+R ++
  462962084 233 YKWPYPSETQKVALAESTGLDLKQINNWFINQRKRH 268
                5679*****************************885 PP
2ELK37.45.4e-13188209122
        ELK   1 ELKhqLlrKYsgyLgsLkqEFs 22 
                ELKh+Ll+KYsgyL+sLkqE+s
  462962084 188 ELKHHLLKKYSGYLSSLKQELS 209
                9*******************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM012555.2E-184491IPR005540KNOX1
PfamPF037901.6E-204590IPR005540KNOX1
SMARTSM012564.8E-2698149IPR005541KNOX2
PfamPF037914.8E-22104147IPR005541KNOX2
SMARTSM01188570107127IPR005539ELK domain
PROSITE profilePS5121311.331188208IPR005539ELK domain
SMARTSM011884.9E-7188209IPR005539ELK domain
PfamPF037896.6E-10188209IPR005539ELK domain
PROSITE profilePS5007112.487208271IPR001356Homeobox domain
SuperFamilySSF466891.97E-19209283IPR009057Homeodomain-like
SMARTSM003895.2E-12210275IPR001356Homeobox domain
Gene3DG3DSA:1.10.10.604.2E-28213273IPR009057Homeodomain-like
CDDcd000862.31E-11220272No hitNo description
PfamPF059205.5E-17228267IPR008422Homeobox KN domain
PROSITE patternPS000270246269IPR017970Homeobox, conserved site
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001708Biological Processcell fate specification
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010051Biological Processxylem and phloem pattern formation
GO:0010089Biological Processxylem development
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 305 aa     Download sequence    Send to blast
MEEITHHFGV GASGHGHHHH PWGSALSAAK EPSSSSPCYA GDVEAIKAKI ISHPHYYSLL  60
AAYLECQKAS PVGAPPEVSA RLTAMAQELE ARQRTTLGGL GSATEPELDQ FMEAYHEMLV  120
KFREELTRPL QEAMEFTRRV ESQLSTLSIS GRSSLRHILS SGSSEEDQEG SGGETELPEV  180
DAHGVDQELK HHLLKKYSGY LSSLKQELSK KKKKGKLPKE ARQQLLLWWE QHYKWPYPSE  240
TQKVALAEST GLDLKQINNW FINQRKRHWK PSEEMHHLMM DGYHTTNAFY MDGHFFNEPG  300
LYRFT
Functional Description ? help Back to Top
Source Description
UniProtBinds to RNA (PubMed:17965274). Possible transcription factor that regulates genes involved in development. Mutations in KN-1 alter leaf development. Foci of cells along the lateral vein do not differentiate properly but continue to divide, forming knots. May participate in the switch from indeterminate to determinate cell fates. Probably binds to the DNA sequence 5'-TGAC-3'. {ECO:0000269|PubMed:17965274}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap462962084
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankDQ3174210.0DQ317421.1 Chasmanthium latifolium KNOTTED1 homeodomain protein (KN1) mRNA, partial cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_025795239.11e-178homeotic protein knotted-1
SwissprotP243451e-175KN1_MAIZE; Homeotic protein knotted-1
TrEMBLA0A3L6TKB21e-180A0A3L6TKB2_PANMI; Homeotic protein knotted-1
STRINGGRMZM2G017087_P021e-174(Zea mays)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP98863145
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G08150.11e-88KNOTTED-like from Arabidopsis thaliana
Publications ? help Back to Top
  1. Lowe B,Mathern J,Hake S
    Active Mutator elements suppress the knotted phenotype and increase recombination at the Kn1-O tandem duplication.
    Genetics, 1992. 132(3): p. 813-22
    [PMID:1334895]
  2. Sinha N,Hake S
    Mutant characters of knotted maize leaves are determined in the innermost tissue layers.
    Dev. Biol., 1990. 141(1): p. 203-10
    [PMID:2391001]
  3. Chen H,Jackson D,Kim JY
    Identification of evolutionarily conserved amino acid residues in homeodomain of KNOX proteins for intercellular trafficking.
    Plant Signal Behav, 2014. 9(3): p. e28355
    [PMID:24603432]
  4. Sinha NR,Williams RE,Hake S
    Overexpression of the maize homeo box gene, KNOTTED-1, causes a switch from determinate to indeterminate cell fates.
    Genes Dev., 1993. 7(5): p. 787-95
    [PMID:7684007]
  5. Greene B,Walko R,Hake S
    Mutator insertions in an intron of the maize knotted1 gene result in dominant suppressible mutations.
    Genetics, 1994. 138(4): p. 1275-85
    [PMID:7896105]
  6. Mathern J,Hake S
    Mu element-generated gene conversions in maize attenuate the dominant knotted phenotype.
    Genetics, 1997. 147(1): p. 305-14
    [PMID:9286690]