PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 55361
Common NameMICPUN_55361
Organism
Micromonas sp. RCC299
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Chlorophyta; prasinophytes; Mamiellophyceae; Mamiellales; Mamiellaceae; Micromonas
Family E2F/DP
Protein Properties Length: 284aa    MW: 31421.4 Da    PI: 4.8602
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
55361genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP74.11.4e-231774870
  E2F_TDP  8 lltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwk 70
             llt+kf++l+ ++e+g+++ln++a+ L   +v  ++RRiYDi+NVLe+++liekk+kn+i wk
    55361 17 LLTKKFISLIDRAEHGTIDLNQAAEVL---KV--QKRRIYDITNVLEGIGLIEKKSKNNILWK 74
             79*************************...88..****************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.104.0E-23974IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013721.0E-251075IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023199.9E-221774IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467851.59E-151773IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF1440741.26E-1688154No hitNo description
PfamPF164213.7E-1989153IPR032198E2F transcription factor, CC-MB domain
CDDcd146601.46E-2789154No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051446Biological Processpositive regulation of meiotic cell cycle
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 284 aa     Download sequence    Send to blast
MHASGTTPCR YDRLSPLLTK KFISLIDRAE HGTIDLNQAA EVLKVQKRRI YDITNVLEGI  60
GLIEKKSKNN ILWKPSASAP AFPEANIMKG NLYIAEEDIK NIPSFSSDTL VAVRAPYGTT  120
LEVPDPDEGD ELSKKRYQIL LKSSSGPVDV FLVSLQGNNG THGPKDSSRQ RKTCLHGQFS  180
KTSDEILLNK QEPGETGSTQ FETGSDAVVL NAHDIFHLET AEASGLKERM FDSPLVADET  240
GFKTPNMLRI VPPPGDQDYW FLQDARDMNM GLQDLFASYD FED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_A3e-21774472PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
14248LKVQKRR
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Regulates gene expression both positively and negatively. Activates the expression of E2FB. Involved in the control of cell-cycle progression from G1 to S phase. Stimulates cell proliferation and delays differentiation. {ECO:0000269|PubMed:11669580, ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11862494, ECO:0000269|PubMed:11889041, ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:12913157, ECO:0000269|PubMed:15377755, ECO:0000269|PubMed:16514015, ECO:0000269|PubMed:19662336}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00293DAPTransfer from AT2G36010Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankCP0015740.0CP001574.1 Micromonas sp. RCC299 chromosome 1, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002507264.10.0e2f1-like protein
SwissprotQ9FNY01e-45E2FA_ARATH; Transcription factor E2FA
TrEMBLC1FE930.0C1FE93_MICCC; E2f1-like protein
STRINGXP_002507264.10.0(Micromonas sp. RCC299)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
ChlorophytaeOGCP32581314
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36010.13e-48E2F transcription factor 3
Publications ? help Back to Top
  1. Worden AZ, et al.
    Green evolution and dynamic adaptations revealed by genomes of the marine picoeukaryotes Micromonas.
    Science, 2009. 324(5924): p. 268-72
    [PMID:19359590]
  2. Magyar Z, et al.
    Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.
    EMBO J., 2012. 31(6): p. 1480-93
    [PMID:22307083]