PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676712266
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family NAC
Protein Properties Length: 561aa    MW: 62315.2 Da    PI: 4.4167
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676712266genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM156.21.4e-48171432128
        NAM   2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgel 99 
                +pGfrFhPtdeelv++yLk+k+ +++l++ ++i  vd+yk++P++Lp +  +k+++++w++F++r +ky++  r+ r t++gyWkatgkd+ ++  +++ 
  676712266  17 APGFRFHPTDEELVMYYLKRKICKRRLRV-NAIGVVDVYKLDPEELPgQsVLKTGDRQWFYFTPRTRKYPNAARSGRCTTTGYWKATGKDRVIVY-NSRS 114
                69***************************.89**************96347788999*************************************9.999* PP

        NAM 100 vglkktLvfykgrapkgektdWvmheyrl 128
                vglkktLvfy+grap+ge+tdWvmhey++
  676712266 115 VGLKKTLVFYRGRAPNGERTDWVMHEYTM 143
                ***************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5100551.84316166IPR003441NAC domain
SuperFamilySSF1019417.32E-5517166IPR003441NAC domain
PfamPF023654.7E-2518142IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0070301Biological Processcellular response to hydrogen peroxide
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 561 aa     Download sequence    Send to blast
MADSSPDSCL KGGKFSAPGF RFHPTDEELV MYYLKRKICK RRLRVNAIGV VDVYKLDPEE  60
LPGQSVLKTG DRQWFYFTPR TRKYPNAARS GRCTTTGYWK ATGKDRVIVY NSRSVGLKKT  120
LVFYRGRAPN GERTDWVMHE YTMDEEELGR CKKAKEYYAL YKLFKKSGAG PKNGEDYGAP  180
FQEEEWVDDN DDEDVGGGDD IAVPEEPVVR VEEDTRRVDN VGLFNPVNVE LDDIEEILNG  240
IPFAPGVPQR CINRLASSIP QVNSAEELQS TLVSNSGREF GEFLPNGQAY PSFESTEVTS  300
APHNSGMGSL VFEKEDYIEI DDLLISELGA SSVENPAEFL NPGEFGDYNE FDQLFHDVSM  360
SLDLEPIADG TSVDPSSLSN FVDNTSNQRQ QVLYQQFQDQ TPDNNLNNVI DPNPNFNQFT  420
DDLWLQDDEQ AVLFDQPSSG VMPGSTNLTT TSVNAQDQEG ENGGGGTSPF SSALWAFMDS  480
IPSTPASACE GPINRTFVRM SSFSRMRFSG KANGTPVTTT VVAKKRSRNK GFLLLSIVGA  540
LCAIFWLFIT TVRASGRPTF S
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A1e-431814317140Stress-induced transcription factor NAC1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
13542RKICKRRL
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction. Binds directly to AOX1A promoter. Mediates mitochondrial retrograde signaling. {ECO:0000269|PubMed:24045017}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00179DAPTransfer from AT1G34190Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap676712266
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cold and drought stresses. {ECO:0000269|PubMed:17158162}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013592194.10.0PREDICTED: NAC domain-containing protein 17-like
SwissprotQ9XIC50.0NAC17_ARATH; NAC domain-containing protein 17
TrEMBLA0A0D3CRV00.0A0A0D3CRV0_BRAOL; Uncharacterized protein
STRINGBo6g044390.10.0(Brassica oleracea)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM28122667
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G34190.10.0NAC domain containing protein 17
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Van Aken O, et al.
    Mitochondrial and Chloroplast Stress Responses Are Modulated in Distinct Touch and Chemical Inhibition Phases.
    Plant Physiol., 2016. 171(3): p. 2150-65
    [PMID:27208304]
  3. Van Aken O,Ford E,Lister R,Huang S,Millar AH
    Retrograde signalling caused by heritable mitochondrial dysfunction is partially mediated by ANAC017 and improves plant performance.
    Plant J., 2016. 88(4): p. 542-558
    [PMID:27425258]
  4. Hu Z, et al.
    Mitochondrial Defects Confer Tolerance against Cellulose Deficiency.
    Plant Cell, 2016. 28(9): p. 2276-2290
    [PMID:27543091]
  5. Chi YH, et al.
    The membrane-tethered NAC transcription factor, AtNTL7, contributes to ER-stress resistance in Arabidopsis.
    Biochem. Biophys. Res. Commun., 2017. 488(4): p. 641-647
    [PMID:28088515]
  6. Van Aken O,Pogson BJ
    Convergence of mitochondrial and chloroplastic ANAC017/PAP-dependent retrograde signalling pathways and suppression of programmed cell death.
    Cell Death Differ., 2017. 24(6): p. 955-960
    [PMID:28498364]
  7. Cheng P, et al.
    The ERA-Related GTPase AtERG2 Associated with Mitochondria 18S RNA Is Essential for Early Embryo Development in Arabidopsis.
    Front Plant Sci, 2018. 9: p. 182
    [PMID:29497438]