PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676718330
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family C2H2
Protein Properties Length: 93aa    MW: 9611.97 Da    PI: 10.9344
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676718330genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H218.46.1e-066688223
               EETTTTEEESSHHHHHHHHHH.T CS
    zf-C2H2  2 kCpdCgksFsrksnLkrHirt.H 23
               +C+ C+k+F++   L++H +  H
  676718330 66 PCGSCKKTFNSEGALESHTKAkH 88
               6*****************99877 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS501579.5366593IPR007087Zinc finger, C2H2
PfamPF128742.8E-56787No hitNo description
PROSITE patternPS0002806788IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 93 aa     Download sequence    Send to blast
AETRKKRAHE AAPKTPVSAK KAKTEVTPKK TEEKKKGGPA TPHPAKKGGK TPTAATPTPK  60
SAGQVPCGSC KKTFNSEGAL ESHTKAKHSA TAN
Functional Description ? help Back to Top
Source Description
UniProtProbably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Required for histone H3 'Lys-9' deacetylation. Involved in rRNA gene silencing in nucleolar dominance. Seems to be implicated in the regulation of genes involved in seeds development. {ECO:0000269|PubMed:10792817, ECO:0000269|PubMed:12694598, ECO:0000269|PubMed:14992728, ECO:0000269|PubMed:15144374}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676718330
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023638513.15e-32histone deacetylase HDT1
SwissprotQ9FVE63e-23HDT1_ARATH; Histone deacetylase HDT1
TrEMBLA0A1J3K2I91e-35A0A1J3K2I9_NOCCA; Histone deacetylase HDT1
STRINGBostr.0556s0764.1.p2e-35(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM20272667
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G44750.22e-09histone deacetylase 3
Publications ? help Back to Top
  1. Song Y,Wu K,Dhaubhadel S,An L,Tian L
    Arabidopsis DNA methyltransferase AtDNMT2 associates with histone deacetylase AtHD2s activity.
    Biochem. Biophys. Res. Commun., 2010. 396(2): p. 187-92
    [PMID:20331964]
  2. Lee K,Park OS,Jung SJ,Seo PJ
    Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis.
    J. Plant Physiol., 2016. 191: p. 95-100
    [PMID:26724747]
  3. Han Z, et al.
    AtHD2D Gene Plays a Role in Plant Growth, Development, and Response to Abiotic Stresses in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 310
    [PMID:27066015]
  4. Li H, et al.
    Plant-Specific Histone Deacetylases HDT1/2 Regulate GIBBERELLIN 2-OXIDASE2 Expression to Control Arabidopsis Root Meristem Cell Number.
    Plant Cell, 2017. 29(9): p. 2183-2196
    [PMID:28855334]