PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676753884
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family NAC
Protein Properties Length: 546aa    MW: 61058.5 Da    PI: 4.7335
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676753884genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM154.93.5e-48151401128
        NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 
                l+pGfrFhPtdeelvv+yLk+k+ +kkl++  +i e+d+yk++P++Lp k  +k+++++w+fFs+rd+k+  g r++rat +gyWkatgkd+ v++ +++
  676753884  15 LAPGFRFHPTDEELVVYYLKRKILRKKLRV-AAIGETDVYKFDPEELPgKaLYKTRDRQWFFFSPRDRKH--GGRSSRATGRGYWKATGKDRVVKC-NSR 110
                579***************************.88***************6446677899**********86..89*********************9.999 PP

        NAM  99 lvglkktLvfykgrapkgektdWvmheyrl 128
                 vg kktLvf++grap+ge+t+Wvmhey+l
  676753884 111 PVGEKKTLVFHRGRAPNGERTNWVMHEYTL 140
                ****************************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019411.27E-5710163IPR003441NAC domain
PROSITE profilePS5100553.57115163IPR003441NAC domain
PfamPF023653.6E-2717140IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010114Biological Processresponse to red light
GO:0010224Biological Processresponse to UV-B
GO:0031930Biological Processmitochondria-nucleus signaling pathway
GO:1900409Biological Processpositive regulation of cellular response to oxidative stress
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 546 aa     Download sequence    Send to blast
MESLTSSCPH ENGGLAPGFR FHPTDEELVV YYLKRKILRK KLRVAAIGET DVYKFDPEEL  60
PGKALYKTRD RQWFFFSPRD RKHGGRSSRA TGRGYWKATG KDRVVKCNSR PVGEKKTLVF  120
HRGRAPNGER TNWVMHEYTL HEEELKRCGD VKDNYVLYKI YKKSGSGPKN GEQYGAPFIE  180
EEWAEDDDDD VDEANVVDVP VNQQLMVSSG MDNNDNTNIW ANGVNQSELN DEDIEELMRQ  240
VRDEPGHVRL SVADPTVQPL SGVNSHVGTY NPVNPERDSY LEIDDLLLPE PEPSYGEAVQ  300
KNWDQDESSV LNDNDFFDFD SYIGDYDATN PQSEPIGVGL ENGFVESLPV NTFPVTDQPN  360
DSQFQQQTWK NQGSNWPLRN SYTRKISSGE SLMHELNNDE LTASRFDEAP GTGDASEFVD  420
PLTSGVSITN GEEATKGESS QFASSIWSIL ESIPANPAYA SENPLVNLNL VRISNLSGRY  480
RLGSKSTGNN VIVAVSNDSS IKRNKSGGNK RNNHKGLFCL SIIGALCALF WVMVGTMGIS  540
RRSLLC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3swm_A8e-46916914174NAC domain-containing protein 19
3swm_B8e-46916914174NAC domain-containing protein 19
3swm_C8e-46916914174NAC domain-containing protein 19
3swm_D8e-46916914174NAC domain-containing protein 19
3swp_A8e-46916914174NAC domain-containing protein 19
3swp_B8e-46916914174NAC domain-containing protein 19
3swp_C8e-46916914174NAC domain-containing protein 19
3swp_D8e-46916914174NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'-CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance. {ECO:0000269|PubMed:24045019}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00176DAPTransfer from AT1G32870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMap676753884
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat, salt stress, abscisic acid (ABA) and methyl methanesulfonate (MMS) treatment. {ECO:0000269|PubMed:17158162}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006416168.10.0NAC domain-containing protein 13
SwissprotF4IED20.0NAC13_ARATH; NAC domain-containing protein 13
TrEMBLV4MRY10.0V4MRY1_EUTSA; Uncharacterized protein
STRINGXP_006416168.10.0(Eutrema salsugineum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM153171517
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32870.10.0NAC domain protein 13
Publications ? help Back to Top
  1. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  2. O'Shea C, et al.
    Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1.
    J. Biol. Chem., 2017. 292(2): p. 512-527
    [PMID:27881680]