PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676754770

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

C2H2

Protein Properties

Length: 274aa MW: 30774.5 Da PI: 8.3017

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676754770	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	15.3	5.8e-05	94	116	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F+++ L H++ H 676754770 94 FECHYCFRNFPTSQALGGHQNAH 116 89******************988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	6.09E-6	90	121	No hit	No description
Pfam	PF13912	2.2E-5	93	118	IPR007087	Zinc finger, C2H2
PROSITE profile	PS50157	10.99	94	121	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	96	116	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009739	Biological Process	response to gibberellin
GO:0010091	Biological Process	trichome branching
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 274 aa Download sequence Send to blast
MDETNGERET QDFMNVESFS QLPFFRRPPS KDKNRKPIRL FGKDFNGGDY FGSSGQEDYS 60 YSSETKKKED EEVEEDDQTG DNCKDNSISN NRRFECHYCF RNFPTSQALG GHQNAHKRER 120 QLAKRGASSY FHHPDANLYG YRNYPSWSSG SSPAARFYGG RTPDPSSSYH TRPINGSPLG 180 LWRVPPSSSS VRGVYNSNAA FTSHGSSNNS TLPFLAGSQP HPPLQVGSSA AQNRMSSYRY 240 DLIPNVQDHL LCGFEVSAMN TIVFGKIQRN GQSY

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor required for the initiation of inflorescence trichomes in response to gibberellin (GA) (PubMed:16679458, PubMed:17507408). Mediates the induction of GL1 expression by GA in inflorescence organs and is antagonized in its action by the DELLA repressor GAI. Acts upstream of the trichome initiation regulators GL1 and GL3, and downstream of the GA signaling repressor SPINDLY (SPY) (PubMed:16679458). Does not play a significant role in the cytokinin response (PubMed:17507408). Controls trichome branching through GA signaling (PubMed:22210898, PubMed:23825141). Acts downstream of the key regulator STICHEL (STI) in an endoreduplication-independent pathway (PubMed:22210898). Controls trichome cell division indirectly by acting downstream of a key endoreduplication regulator SIAMESE (SIM) (PubMed:23825141). {ECO:0000269\|PubMed:16679458, ECO:0000269\|PubMed:17507408, ECO:0000269\|PubMed:22210898, ECO:0000269\|PubMed:23825141}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676754770

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By gibberellin. {ECO:0000269\|PubMed:16679458}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009116503.1	1e-143	PREDICTED: zinc finger protein GIS
Refseq	XP_013659894.1	1e-143	zinc finger protein GIS-like
Swissprot	Q84WI0	1e-105	GIS_ARATH; Zinc finger protein GIS
TrEMBL	A0A397Y2E0	1e-141	A0A397Y2E0_BRACM; Uncharacterized protein
TrEMBL	M4CT36	1e-141	M4CT36_BRARP; Uncharacterized protein
STRING	Bra007378.1-P	1e-142	(Brassica rapa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM2495	19	49

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G58070.1	3e-95	C2H2 family protein

Publications ? help Back to Top
Sun L, et al. GLABROUS INFLORESCENCE STEMS3 (GIS3) regulates trichome initiation and development in Arabidopsis. New Phytol., 2015. 206(1): p. 220-30 [PMID:25640859] Yu D, et al. RPN1a, a subunit of the 26S proteasome, controls trichome development in Arabidopsis. Plant Physiol. Biochem., 2015. 88: p. 82-8 [PMID:25676129] Liu Y, et al. AtGIS, a C2H2 zinc-finger transcription factor from Arabidopsis regulates glandular trichome development through GA signaling in tobacco. Biochem. Biophys. Res. Commun., 2017. 483(1): p. 209-215 [PMID:28034756] Vadde BVL,Challa KR,Nath U The TCP4 transcription factor regulates trichome cell differentiation by directly activating GLABROUS INFLORESCENCE STEMS in Arabidopsis thaliana. Plant J., 2018. 93(2): p. 259-269 [PMID:29165850] Kim SY,Hyoung S,So WM,Shin JS The novel transcription factor TRP interacts with ZFP5, a trichome initiation-related transcription factor, and negatively regulates trichome initiation through gibberellic acid signaling. Plant Mol. Biol., 2018. 96(3): p. 315-326 [PMID:29335898]