PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676758160

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

C2H2

Protein Properties

Length: 473aa MW: 52146.3 Da PI: 5.7526

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676758160	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	12.5	0.00045	127	149	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++Cp+Cg +F++ ++ H ++ 676758160 127 FECPICGNPFKSEEEVSEHVESC 149 89*************99998776 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50157	8.517	127	161	IPR007087	Zinc finger, C2H2
SuperFamily	SSF143503	1.44E-18	187	269	IPR018997	PUB domain
CDD	cd09212	7.13E-22	190	273	No hit	No description
Pfam	PF09409	9.3E-18	190	263	IPR018997	PUB domain
SMART	SM00580	2.6E-24	191	258	IPR018997	PUB domain
SuperFamily	SSF54236	9.82E-12	339	448	IPR029071	Ubiquitin-related domain
PROSITE profile	PS50033	10.052	364	448	IPR001012	UBX domain
Gene3D	G3DSA:3.10.20.90	4.1E-7	364	447	No hit	No description
Pfam	PF00789	8.4E-5	366	415	IPR001012	UBX domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0050832	Biological Process	defense response to fungus
GO:0005515	Molecular Function	protein binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 473 aa Download sequence Send to blast
MNDVKDKLKG FMKKVNLSSS SGKFKGSGRV LGSSSSSAPV NPIQNRFNPP QPSKPNPNPT 60 PRPTKPSPSP SSGSSSAPLP EKIPSSGSTK NPDPVPVRAP PQDGFDPYGA LITSSNRSQN 120 GYTLDMFECP ICGNPFKSEE EVSEHVESCL GDTTTNGGDK SASEKMDTDV EDKSEVEKLV 180 VVYLSGKPTE SSVDVLLRLF KNIVKEPENG KFRKIRMSNA KIKEAIGDVP GGVELLELVG 240 FVLKEENDEV WAVMEVPRDE QTQLINKVVG ILENSKTETP AKDDISGSSV AEEPVVPKKI 300 DREIRVFFSV AENVASRIEV PDSFYSLSAD EIKREADLRR KKIAESQLLI PRSYREKQAK 360 AARRRYKRSM IRVQFPDGVV LQGVFAPWEP TIALYEFVSS ALKEASLQFE LLDPVLVKRR 420 VIPHTPAPGQ KPRTLEDEEL VPSALIKFRP IETDSLVFTG LRNELLEISE PMS

Sequence ? help Back to Top

Protein Sequence Length: 473 aa Download sequence Send to blast

MNDVKDKLKG FMKKVNLSSS SGKFKGSGRV LGSSSSSAPV NPIQNRFNPP QPSKPNPNPT  60
PRPTKPSPSP SSGSSSAPLP EKIPSSGSTK NPDPVPVRAP PQDGFDPYGA LITSSNRSQN  120
GYTLDMFECP ICGNPFKSEE EVSEHVESCL GDTTTNGGDK SASEKMDTDV EDKSEVEKLV  180
VVYLSGKPTE SSVDVLLRLF KNIVKEPENG KFRKIRMSNA KIKEAIGDVP GGVELLELVG  240
FVLKEENDEV WAVMEVPRDE QTQLINKVVG ILENSKTETP AKDDISGSSV AEEPVVPKKI  300
DREIRVFFSV AENVASRIEV PDSFYSLSAD EIKREADLRR KKIAESQLLI PRSYREKQAK  360
AARRRYKRSM IRVQFPDGVV LQGVFAPWEP TIALYEFVSS ALKEASLQFE LLDPVLVKRR  420
VIPHTPAPGQ KPRTLEDEEL VPSALIKFRP IETDSLVFTG LRNELLEISE PMS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5ifw_A	1e-11	319	448	23	146	Tether containing UBX domain for GLUT4
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	361	369	ARRRYKRSM

Functional Description ? help Back to Top
Source	Description
UniProt	Facilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269\|PubMed:19176722, ECO:0000269\|PubMed:23301616, ECO:0000269\|Ref.8}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676758160

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269\|PubMed:19176722}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006291059.1	0.0	plant UBX domain-containing protein 2
Refseq	XP_013707193.1	0.0	plant UBX domain-containing protein 2-like
Swissprot	Q9ZU93	0.0	PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBL	R0FNB3	0.0	R0FNB3_9BRAS; Uncharacterized protein
STRING	XP_006291059.1	0.0	(Capsella rubella)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9835	16	18

Publications ? help Back to Top
Suzuki T,Park H,Till EA,Lennarz WJ The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway. Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7 [PMID:11587532] Rancour DM,Park S,Knight SD,Bednarek SY Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48. J. Biol. Chem., 2004. 279(52): p. 54264-74 [PMID:15498773] Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction. Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45 [PMID:23301616]