PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676762620
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family B3
Protein Properties Length: 739aa    MW: 84089.9 Da    PI: 7.8941
Description B3 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676762620genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1B3505.3e-16484578199
                EEEE-..-HHHHTT-EE--HHH.HTT---..--SEEEEEETTS-EEEEEE..EEETTEEEE-.TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEEE-S CS
         B3   1 ffkvltpsdvlksgrlvlpkkfaeehggkkeesktltledesgrsWevkliyrkksgryvlt.kGWkeFvkangLkegDfvvFkldgrsefelvvkvfrk 99 
                ffk+l  +d +++++  +p +f+++ + k + + +++l+  +grsW+v l  +k  g y+++ kGW++F ++n+L + +f++F+ +g+++   +v +f+k
  676762620 484 FFKILADKDLSSESMRLIPHEFVRRSECK-NLPLKVILKVVWGRSWTVSL--SKFMGYYLMErKGWEKFLNDNQLGDDEFLTFTNEGNNCL--TVDIFQK 578
                99*********************999654.6999****************..888888555449********************7666666..9999987 PP
2B355.79e-186597341596
                -EE--HHH.HTT---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE-SSSEE..EEEE CS
         B3  15 rlvlpkkfaeehggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkldgrsefelvvkv 96 
                +l++pk+fa+eh+ k  + ++ ++ d++g+ Wev +  ++++g+ ++++GW+  v+  gL +gDf++F+l++   +e+v+ v
  676762620 659 LLTIPKDFANEHMPK--QRTKYIIHDPKGKPWEVVC--TNSGGSKLFSSGWRFLVRGYGLAVGDFCTFRLIKP--KEMVLEV 734
                589*********844..6679999************..*******************************9974..4445555 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
HamapMF_0317546.78412438IPR002468Peptidase M24A, methionine aminopeptidase, subfamily 2
SuperFamilySSF559203.4E-8077335IPR000994Peptidase M24, structural domain
CDDcd010880126433No hitNo description
Gene3DG3DSA:3.90.230.102.8E-86127332IPR000994Peptidase M24, structural domain
PfamPF005571.0E-42128425IPR000994Peptidase M24, structural domain
TIGRFAMsTIGR005013.4E-102129430IPR002468Peptidase M24A, methionine aminopeptidase, subfamily 2
PRINTSPR005991.0E-15181194IPR001714Peptidase M24, methionine aminopeptidase
PRINTSPR005991.0E-15206222IPR001714Peptidase M24, methionine aminopeptidase
PROSITE patternPS012020206222IPR018349Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site
PRINTSPR005991.0E-15282294IPR001714Peptidase M24, methionine aminopeptidase
PRINTSPR005991.0E-15313325IPR001714Peptidase M24, methionine aminopeptidase
Gene3DG3DSA:1.10.10.101.3E-39333410IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467857.75E-22336407IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF559203.4E-80409433IPR000994Peptidase M24, structural domain
Gene3DG3DSA:3.90.230.102.8E-86412431IPR000994Peptidase M24, structural domain
Gene3DG3DSA:2.40.330.101.5E-17478580IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019367.85E-17479583IPR015300DNA-binding pseudobarrel domain
CDDcd100179.14E-16483576No hitNo description
SMARTSM010199.3E-16484579IPR003340B3 DNA binding domain
PROSITE profilePS5086313.112484579IPR003340B3 DNA binding domain
PfamPF023622.5E-14484578IPR003340B3 DNA binding domain
Gene3DG3DSA:2.40.330.102.0E-20640736IPR015300DNA-binding pseudobarrel domain
SuperFamilySSF1019362.94E-21641736IPR015300DNA-binding pseudobarrel domain
PROSITE profilePS5086313.253645738IPR003340B3 DNA binding domain
CDDcd100172.42E-15646735No hitNo description
SMARTSM010198.4E-15648738IPR003340B3 DNA binding domain
PfamPF023626.4E-15658731IPR003340B3 DNA binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006508Biological Processproteolysis
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0004177Molecular Functionaminopeptidase activity
GO:0008235Molecular Functionmetalloexopeptidase activity
Sequence ? help Back to Top
Protein Sequence    Length: 739 aa     Download sequence    Send to blast
MEIEKLDVQA SMEENNGAES SNGKEAQLAS DFSKNLDLAE DENEDKQEEE GNKAESSTKK  60
KKKKSRSRKK KKSSLQQTDP PSIPVIELFP SGEFPEGEIQ QYKDDNLWRI TSEEKREMER  120
LQKPIYNSLR QAAEVHRQVR KYMRSIMKPG MLMIEICETL ENTVRKLISE NGLQAGIAFP  180
TGCSLNNVAA HWTPNSGDKT VLQYDDVMKL DFGTHIDGYI VDSAFTVAFD PMYDPLLAAS  240
REATYTGIKE AGVDVRLCDV GAAIQEVMES YEVEINGKVY QVKSIRNLNG HSIGRYQIHA  300
EKSVPNVRRG EQTKMEEGEL YAIETFGSTG KGYVRDDLEC SHYMKNYDVG HVPLRLPRAK  360
QLLATINKNF STLAFCRRYL DRIGETKYLM ALKNLCDSGI IEPCPPVCDV KGSYVSQFEH  420
TILLRPTCKE LSSLLSRDRE SKREERDSES ETLKEEKRKR SCLHEMARNR AFGRIQEDQK  480
KTSFFKILAD KDLSSESMRL IPHEFVRRSE CKNLPLKVIL KVVWGRSWTV SLSKFMGYYL  540
MERKGWEKFL NDNQLGDDEF LTFTNEGNNC LTVDIFQKNC KEILKPLKTT ITASSSSFSG  600
VKKEKMSCVD PVIAESTRRG AKEKERAEEE EEMKNVNGAS SSPSVPTFSL TIKQSHLLLL  660
TIPKDFANEH MPKQRTKYII HDPKGKPWEV VCTNSGGSKL FSSGWRFLVR GYGLAVGDFC  720
TFRLIKPKEM VLEVLHASP
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1b59_A0.0774334365PROTEIN (METHIONINE AMINOPEPTIDASE)
5cls_A0.0774335366Methionine aminopeptidase 2
5d6e_A0.0774335366Methionine aminopeptidase 2
5d6f_A0.0774335366Methionine aminopeptidase 2
5jfr_A0.0774333364Methionine aminopeptidase 2
5jhu_A0.0774333364Methionine aminopeptidase 2
5ji6_A0.0774333364Methionine aminopeptidase 2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
15869KKKKKKSRSRKK
25971KKKKKSRSRKKKK
Functional Description ? help Back to Top
Source Description
UniProtCotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). {ECO:0000255|HAMAP-Rule:MF_03175}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676762620
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK2282840.0AK228284.1 Arabidopsis thaliana mRNA for methionine aminopeptidase-like protein, complete cds, clone: RAFL14-73-C05.
GenBankBT0064760.0BT006476.1 Arabidopsis thaliana At2g44180 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_013626324.10.0PREDICTED: methionine aminopeptidase 2A
RefseqXP_022554886.10.0methionine aminopeptidase 2A-like
SwissprotQ9FV490.0MAP21_ARATH; Methionine aminopeptidase 2A
TrEMBLA0A397ZXI10.0A0A397ZXI1_BRACM; Methionine aminopeptidase 2
STRINGBo3g037150.10.0(Brassica oleracea)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G18090.15e-62B3 family protein
Publications ? help Back to Top
  1. Giglione C,Serero A,Pierre M,Boisson B,Meinnel T
    Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.
    EMBO J., 2000. 19(21): p. 5916-29
    [PMID:11060042]
  2. Sokolenko A, et al.
    The gene complement for proteolysis in the cyanobacterium Synechocystis sp. PCC 6803 and Arabidopsis thaliana chloroplasts.
    Curr. Genet., 2002. 41(5): p. 291-310
    [PMID:12185496]
  3. Ross S,Giglione C,Pierre M,Espagne C,Meinnel T
    Functional and developmental impact of cytosolic protein N-terminal methionine excision in Arabidopsis.
    Plant Physiol., 2005. 137(2): p. 623-37
    [PMID:15681659]