PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

676781692

Organism

Sisymbrium irio

Taxonomic ID

3730

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium

Family

MYB

Protein Properties

Length: 960aa MW: 107318 Da PI: 5.1875

Description

MYB family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
676781692	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	59	1.1e-18	37	83	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 rg WT+eEde+l++av+ + g++Wk+Ia+++ Rt+ qc +rwqk+l 676781692 37 RGQWTAEEDEILKKAVHSFKGKNWKKIAEYFK-DRTDVQCLHRWQKVL 83 89***************************9.**********986 PP
2	Myb_DNA-binding	62.8	6.9e-20	89	135	1	48
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 +g+WT+eEde +v++++++G++ W+tIar ++ gR +kqc++rw+++l 676781692 89 KGPWTKEEDEMIVQLIQKYGPKKWSTIARFLP-GRIGKQCRERWHNHL 135 79****************************.***********97 PP
3	Myb_DNA-binding	43	1e-13	141	183	1	45
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwq 45 + +WT+eE++ l++a++ +G++ W+ + ++ gR+++ +k++w+ 676781692 141 KEAWTQEEELVLIRAHQIYGNR-WAELTKFLP-GRSDNGIKNHWH 183 579*****************.*****.*********8 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51294	19.096	32	83	IPR017930	Myb domain
SuperFamily	SSF46689	2.44E-15	34	89	IPR009057	Homeodomain-like
SMART	SM00717	9.2E-16	36	85	IPR001005	SANT/Myb domain
Pfam	PF00249	2.0E-16	37	83	IPR001005	SANT/Myb domain
Gene3D	G3DSA:1.10.10.60	7.1E-23	39	91	IPR009057	Homeodomain-like
CDD	cd00167	3.86E-14	40	83	No hit	No description
PROSITE profile	PS51294	32.297	84	139	IPR017930	Myb domain
SuperFamily	SSF46689	1.2E-31	86	182	IPR009057	Homeodomain-like
SMART	SM00717	5.1E-19	88	137	IPR001005	SANT/Myb domain
Pfam	PF00249	1.1E-17	89	135	IPR001005	SANT/Myb domain
CDD	cd00167	9.91E-17	91	135	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.1E-27	92	139	IPR009057	Homeodomain-like
Gene3D	G3DSA:1.10.10.60	1.6E-19	140	190	IPR009057	Homeodomain-like
SMART	SM00717	1.5E-12	140	188	IPR001005	SANT/Myb domain
PROSITE profile	PS51294	18.094	140	190	IPR017930	Myb domain
Pfam	PF00249	9.6E-12	141	183	IPR001005	SANT/Myb domain
CDD	cd00167	1.02E-9	143	183	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0032875	Biological Process	regulation of DNA endoreduplication
GO:0003677	Molecular Function	DNA binding
GO:0003713	Molecular Function	transcription coactivator activity

Sequence ? help Back to Top
Protein Sequence Length: 960 aa Download sequence Send to blast
MESECAATIS TPPVGIPEAN PKSRHGRTSG PARRSTRGQW TAEEDEILKK AVHSFKGKNW 60 KKIAEYFKDR TDVQCLHRWQ KVLNPELVKG PWTKEEDEMI VQLIQKYGPK KWSTIARFLP 120 GRIGKQCRER WHNHLNPAIN KEAWTQEEEL VLIRAHQIYG NRWAELTKFL PGRSDNGIKN 180 HWHSSVKKKL DSYMSSGLLD QYQAMPLAPY DKSTALQSAF MRSTMDGIGC VSGREEKEIE 240 NCQISSMAGC SISARDYQNG MMNMTQQFHP CENSNKNERA AYHSDQYYYP ELEDISVSIS 300 EASYDMEDCS QFPDHNVSAS SSQDYQFDFQ DLSDISLEMR HNMSELPMPY TKESKESSLG 360 APNSTSNIDV ATCTNPANVS TSETECCRVL FLDQESEGLS VSKSSTQEPN EVDQADYQDS 420 FVCASASESQ TSEATKSPMQ SSSSKSIATA ASGKETLRPA PLIISPEKYS KKSSGLICHP 480 FEAEPNCQTN ENGSFICISD PSTSTCVDEG TNNSSEDQSY HLNDSKKLVP VNDFASLAEV 540 NPHSLPKHEP NMSSEQHHED MGASSSLCFP SLDLPAFNDP LHDYSPLGIR KLLMSTMTCM 600 SPLRLWESPT GKKTLVGAKS VLRKRTRDLL TPLSEKRSDK KLEIDIAASL AKDFSRLDVM 660 FDESESRESI SGTNTGVNLG DKENHFQNLN GEDEESWRGK PTLLSSHRMP EETMDIRKSL 720 KNPEQTCLEA KVRQKDDSEP DVEKAESFSG VLSENNTNKQ VLSPPGQSVT KAEKAQVSTP 780 RNHLQRTLMA TSNKEQHASA SLCLVINSPS RARNSESHLV NNETGNENFS IFCGTPFRRG 840 LESPSAWKSP FYVNSLLPSP RFDTEITIED MGYIFSPGER SYESIGMMTQ RNEHASAFAA 900 FEAMEVSFSP SIDDARKMKD LDKENNDPLL AEGRVLDFND CESPTKVTEE VSSYLLKGCR

Sequence ? help Back to Top

Protein Sequence Length: 960 aa Download sequence Send to blast

MESECAATIS TPPVGIPEAN PKSRHGRTSG PARRSTRGQW TAEEDEILKK AVHSFKGKNW  60
KKIAEYFKDR TDVQCLHRWQ KVLNPELVKG PWTKEEDEMI VQLIQKYGPK KWSTIARFLP  120
GRIGKQCRER WHNHLNPAIN KEAWTQEEEL VLIRAHQIYG NRWAELTKFL PGRSDNGIKN  180
HWHSSVKKKL DSYMSSGLLD QYQAMPLAPY DKSTALQSAF MRSTMDGIGC VSGREEKEIE  240
NCQISSMAGC SISARDYQNG MMNMTQQFHP CENSNKNERA AYHSDQYYYP ELEDISVSIS  300
EASYDMEDCS QFPDHNVSAS SSQDYQFDFQ DLSDISLEMR HNMSELPMPY TKESKESSLG  360
APNSTSNIDV ATCTNPANVS TSETECCRVL FLDQESEGLS VSKSSTQEPN EVDQADYQDS  420
FVCASASESQ TSEATKSPMQ SSSSKSIATA ASGKETLRPA PLIISPEKYS KKSSGLICHP  480
FEAEPNCQTN ENGSFICISD PSTSTCVDEG TNNSSEDQSY HLNDSKKLVP VNDFASLAEV  540
NPHSLPKHEP NMSSEQHHED MGASSSLCFP SLDLPAFNDP LHDYSPLGIR KLLMSTMTCM  600
SPLRLWESPT GKKTLVGAKS VLRKRTRDLL TPLSEKRSDK KLEIDIAASL AKDFSRLDVM  660
FDESESRESI SGTNTGVNLG DKENHFQNLN GEDEESWRGK PTLLSSHRMP EETMDIRKSL  720
KNPEQTCLEA KVRQKDDSEP DVEKAESFSG VLSENNTNKQ VLSPPGQSVT KAEKAQVSTP  780
RNHLQRTLMA TSNKEQHASA SLCLVINSPS RARNSESHLV NNETGNENFS IFCGTPFRRG  840
LESPSAWKSP FYVNSLLPSP RFDTEITIED MGYIFSPGER SYESIGMMTQ RNEHASAFAA  900
FEAMEVSFSP SIDDARKMKD LDKENNDPLL AEGRVLDFND CESPTKVTEE VSSYLLKGCR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1h88_C	7e-69	37	190	6	159	MYB PROTO-ONCOGENE PROTEIN
1h89_C	7e-69	37	190	6	159	MYB PROTO-ONCOGENE PROTEIN
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor that binds 5'-AACGG-3' motifs in gene promoters (PubMed:21862669). Involved in the regulation of cytokinesis, probably via the activation of several G2/M phase-specific genes transcription (e.g. KNOLLE) (PubMed:17287251, PubMed:21862669, PubMed:25806785). Required for the maintenance of diploidy (PubMed:21862669). {ECO:0000269\|PubMed:17287251, ECO:0000269\|PubMed:21862669, ECO:0000269\|PubMed:25806785}.; FUNCTION: Involved in transcription regulation during induced endoreduplication at the powdery mildew (e.g. G.orontii) infection site, thus promoting G.orontii growth and reproduction. {ECO:0000269\|PubMed:20018666}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00505	DAP	Transfer from AT5G11510	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	676781692

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Slightly induced by salicylic acid (SA) (PubMed:16463103). Expressed in a cell cycle-dependent manner, with highest levels 2 hours before the peak of mitotic index in cells synchronized by aphidicolin. Activated by CYCB1 (PubMed:17287251). Accumulates at powdery mildew (e.g. G.orontii) infected cells. {ECO:0000269\|PubMed:16463103, ECO:0000269\|PubMed:17287251}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AF371975	0.0	AF371975.2 Arabidopsis thaliana putative c-myb-like transcription factor MYB3R-4 (MYB3R4) mRNA, complete cds.
GenBank	AY519650	0.0	AY519650.1 Arabidopsis thaliana MYB transcription factor (At5g11510) mRNA, complete cds.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006399657.1	0.0	transcription factor MYB3R-4
Swissprot	Q94FL9	0.0	MB3R4_ARATH; Transcription factor MYB3R-4
TrEMBL	V4KT42	0.0	V4KT42_EUTSA; Uncharacterized protein
STRING	XP_006399657.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM13213	18	28

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G11510.1	0.0	myb domain protein 3r-4

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Saito T, et al. Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana. Plant Signal Behav, 2015. 10(3): p. e990817 [PMID:25806785] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325] Chen P, et al. Arabidopsis R1R2R3-Myb proteins are essential for inhibiting cell division in response to DNA damage. Nat Commun, 2017. 8(1): p. 635 [PMID:28935922]