PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 676787962
Organism
Sisymbrium irio
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Sisymbrieae; Sisymbrium
Family GRF
Protein Properties Length: 309aa    MW: 34640.3 Da    PI: 7.8185
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
676787962genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC43.84.6e-14144172129
        WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCE 29 
                d+epgrCrRtDGKkWRCsr+v +g++  E
  676787962 144 DPEPGRCRRTDGKKWRCSRDVFAGHNCSE 172
                79**********************98655 PP
2QLQ54.14.7e-1975111137
        QLQ   1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                s F++aQ+q+L+ Q+l+y+y++a++ vP+eLl++i+k
  676787962  75 SFFSWAQWQELELQALIYRYMLAGAAVPQELLLPIKK 111
                67*********************************86 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009515.3E-1275111IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166620.24776111IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088804.9E-1377109IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166715.527144188IPR014977WRC domain
PfamPF088792.5E-10145169IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 309 aa     Download sequence    Send to blast
MDLQLKQWRS QQVQQQQTES DEQPSAAKIP KHVFDQLQSH TATSTALPLF TPEPTSSKLS  60
SLSHDSSSRF PKMGSFFSWA QWQELELQAL IYRYMLAGAA VPQELLLPIK KSLLHLSPSY  120
FLHHPLQHLP HYQPAWYLGR AAMDPEPGRC RRTDGKKWRC SRDVFAGHNC SEMKQESNNN  180
NKRPYESHPG FGNNRSDGGH ILRHFFDDWP RSEVDNSSSP MSSATCLSIS MPGNSSSDVS  240
LKLSTGNEEE ARSNNNGRDQ QNMSWWSGGG SHHNHHHMGG PLAEALRSSS SSSPTSVLHQ  300
LGVSTQAFH
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269|PubMed:12974814, ECO:0000269|PubMed:22419826}.
Cis-element ? help Back to Top
SourceLink
PlantRegMap676787962
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503, ECO:0000269|PubMed:20023165, ECO:0000269|PubMed:22419826}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1174170.0AK117417.1 Arabidopsis thaliana At2g36400 mRNA for unknown protein, complete cds, clone: RAFL17-02-B13.
GenBankAY1026360.0AY102636.1 Arabidopsis thaliana transcription activator (GRF3) mRNA, complete cds.
GenBankBT0264720.0BT026472.1 Arabidopsis thaliana At2g36400 mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020881384.11e-111growth-regulating factor 4
SwissprotQ9SJR51e-100GRF3_ARATH; Growth-regulating factor 3
TrEMBLA0A078I1P71e-171A0A078I1P7_BRANA; BnaAnng07360D protein
TrEMBLA0A3P6CQW11e-171A0A3P6CQW1_BRACM; Uncharacterized protein
STRINGBra017240.1-P1e-167(Brassica rapa)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM19262667
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G36400.14e-68growth-regulating factor 3
Publications ? help Back to Top
  1. Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P
    Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves.
    Plant Cell, 2013. 25(9): p. 3570-83
    [PMID:24076976]
  2. Vercruyssen L, et al.
    ANGUSTIFOLIA3 binds to SWI/SNF chromatin remodeling complexes to regulate transcription during Arabidopsis leaf development.
    Plant Cell, 2014. 26(1): p. 210-29
    [PMID:24443518]
  3. Liu J,Rice JH,Chen N,Baum TJ,Hewezi T
    Synchronization of developmental processes and defense signaling by growth regulating transcription factors.
    PLoS ONE, 2014. 9(5): p. e98477
    [PMID:24875638]
  4. Cao Y,Han Y,Jin Q,Lin Y,Cai Y
    Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
    Front Plant Sci, 2016. 7: p. 1750
    [PMID:27933074]