PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

678451793

Organism

Utricularia gibba

Taxonomic ID

13748

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Lamiales; Lentibulariaceae; Utricularia

Family

E2F/DP

Protein Properties

Length: 480aa MW: 53382.1 Da PI: 4.6067

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
678451793	genome	UGSP	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	80.2	1.8e-25	146	207	6	71
E2F_TDP 6 LrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 L+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg 678451793 146 LGLLTKKFINLIKHAEDGILDLNKAADTL---EV-VQKRRIYDITNVLEGIGLIEKKLKNRIQWKG 207 99*************************...55.5**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SMART	SM01372	6.1E-29	141	207	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	1.1E-25	145	208	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	2.58E-15	146	205	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	3.3E-22	146	207	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	2.28E-44	218	324	No hit	No description
SuperFamily	SSF144074	1.94E-32	220	324	No hit	No description
Pfam	PF16421	3.2E-32	223	322	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 480 aa Download sequence Send to blast
MQPAEKQPLR RQLMVDSKRP PFGRGVGGEY HHFVDDEMRN PPRDFDEGIV VRTPPALKRK 60 GGKPESELES GKLGGSSSVS PLQVCNQTPP TVKSGKNQKV PRTTKPSKIG PQVPVTNIGS 120 PSGNNLTPGP CRYDSSLVVK IHLTVLGLLT KKFINLIKHA EDGILDLNKA ADTLEVVQKR 180 RIYDITNVLE GIGLIEKKLK NRIQWKGIDV HRPGDDVESL PSLQMDVENL NTEESTLDER 240 IREMQEKLRG LSEDDNNKKW LFVTEEDIKG LPCFQNETLI AIKAPHGTTL EVPDPDEAVD 300 YPHRRYRIVL RSTMGPIDVY LVSQFVENFD DNNASEMQES APEMVLTEEY PSNPIAVDDI 360 KGNEFDLQQI EPQRICSDAT TSQDFSSGIM KIIPDVDDEA DYWLLSDADT SLTNIWGVES 420 GVDWNSLETV LEDQLMLCIP TSPTPSLPPP PAGHLPCDIS QHQNNPTGTT TPSTTSENRI

Sequence ? help Back to Top

Protein Sequence Length: 480 aa Download sequence Send to blast

MQPAEKQPLR RQLMVDSKRP PFGRGVGGEY HHFVDDEMRN PPRDFDEGIV VRTPPALKRK  60
GGKPESELES GKLGGSSSVS PLQVCNQTPP TVKSGKNQKV PRTTKPSKIG PQVPVTNIGS  120
PSGNNLTPGP CRYDSSLVVK IHLTVLGLLT KKFINLIKHA EDGILDLNKA ADTLEVVQKR  180
RIYDITNVLE GIGLIEKKLK NRIQWKGIDV HRPGDDVESL PSLQMDVENL NTEESTLDER  240
IREMQEKLRG LSEDDNNKKW LFVTEEDIKG LPCFQNETLI AIKAPHGTTL EVPDPDEAVD  300
YPHRRYRIVL RSTMGPIDVY LVSQFVENFD DNNASEMQES APEMVLTEEY PSNPIAVDDI  360
KGNEFDLQQI EPQRICSDAT TSQDFSSGIM KIIPDVDDEA DYWLLSDADT SLTNIWGVES  420
GVDWNSLETV LEDQLMLCIP TSPTPSLPPP PAGHLPCDIS QHQNNPTGTT TPSTTSENRI

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	5e-25	142	208	8	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	678451793

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_011090314.1	0.0	transcription factor E2FB isoform X1
Swissprot	Q9FV71	1e-123	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A2R6P735	1e-177	A0A2R6P735_ACTCH; Transcription factor E2FB like
STRING	Migut.N02463.1.p	1e-179	(Erythranthe guttata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA1077	24	84

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-123	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]