PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID 94010
Common NameICE, SELMODRAFT_138758, SELMODRAFT_94010
Organism
Selaginella moellendorffii
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Lycopodiidae; Selaginellales; Selaginellaceae; Selaginella
Family bHLH
Protein Properties Length: 219aa    MW: 23631.3 Da    PI: 7.8142
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
94010genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH38.12.8e-122668754
           HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
    HLH  7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54
           ++ErrRR+++N+++  Lr+++Pk      +K++ a+iL  A+eY+k+L
  94010 26 MAERRRRKKLNDRLYMLRSVVPKI-----TKMDRASILGDAIEYLKEL 68
           79*********************7.....7****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.5991968IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474594.97E-172281IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000106.6E-102568IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003534.1E-142574IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.105.1E-162680IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000834.10E-132672No hitNo description
CDDcd048731.84E-7148207No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010444Biological Processguard mother cell differentiation
GO:0050826Biological Processresponse to freezing
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 219 aa     Download sequence    Send to blast
MGGHQVADKG PSGRGNRKGL PAKNLMAERR RRKKLNDRLY MLRSVVPKIT KMDRASILGD  60
AIEYLKELLQ RINELHSELE GPADGGSMGI PPQQQSGALL SPQSFAPCVK EECPASSISP  120
LPLLPGPPTD LQPAKVEVRT RDGKGINIHM FCARTPGLLL STMRALDDLG LDVQQAVISC  180
FNGFVLDVFR AEQCSDAEIA PEEIKAVLLQ TAGCHEAL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A5e-142178663Transcription factor MYC2
5gnj_B5e-142178663Transcription factor MYC2
5gnj_E5e-142178663Transcription factor MYC2
5gnj_F5e-142178663Transcription factor MYC2
5gnj_G5e-142178663Transcription factor MYC2
5gnj_I5e-142178663Transcription factor MYC2
5gnj_M5e-142178663Transcription factor MYC2
5gnj_N5e-142178663Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
12734ERRRRKKL
Functional Description ? help Back to Top
Source Description
UniProtMediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (PubMed:18641265). Functions as a dimer with SPCH during stomatal initiation (PubMed:18641265, PubMed:28507175). {ECO:0000269|PubMed:18641265, ECO:0000269|PubMed:28507175}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002970916.21e-155transcription factor SCREAM2 isoform X2
RefseqXP_002994520.21e-155transcription factor SCREAM2 isoform X2
SwissprotQ9LPW38e-81SCRM2_ARATH; Transcription factor SCREAM2
TrEMBLD8RIG61e-157D8RIG6_SELML; Uncharacterized protein ICE
STRINGEFJ044171e-158(Selaginella moellendorffii)
STRINGEFJ282421e-158(Selaginella moellendorffii)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP5571678
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G12860.19e-79bHLH family protein
Publications ? help Back to Top
  1. Tarasov VA,Khadeeva NV,Mel'nik VA,Ezhova TA,Shestakov SV
    The Atlg12860 gene of Arabidopsis thaliana determines cathelicidin-like antimicrobial activity.
    Dokl. Biol. Sci., 2009.
    [PMID:19760875]
  2. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  3. Banks JA, et al.
    The Selaginella genome identifies genetic changes associated with the evolution of vascular plants.
    Science, 2011. 332(6032): p. 960-3
    [PMID:21551031]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Emmerstorfer A, et al.
    Over-expression of ICE2 stabilizes cytochrome P450 reductase in Saccharomyces cerevisiae and Pichia pastoris.
    Biotechnol J, 2015. 10(4): p. 623-35
    [PMID:25641738]
  6. Lee HG,Seo PJ
    The MYB96-HHP module integrates cold and abscisic acid signaling to activate the CBF-COR pathway in Arabidopsis.
    Plant J., 2015. 82(6): p. 962-77
    [PMID:25912720]
  7. Raissig MT,Abrash E,Bettadapur A,Vogel JP,Bergmann DC
    Grasses use an alternatively wired bHLH transcription factor network to establish stomatal identity.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(29): p. 8326-31
    [PMID:27382177]
  8. Fu ZW,Wang YL,Lu YT,Yuan TT
    Nitric oxide is involved in stomatal development by modulating the expression of stomatal regulator genes in Arabidopsis.
    Plant Sci., 2016. 252: p. 282-289
    [PMID:27717464]
  9. de Marcos A, et al.
    A Mutation in the bHLH Domain of the SPCH Transcription Factor Uncovers a BR-Dependent Mechanism for Stomatal Development.
    Plant Physiol., 2017. 174(2): p. 823-842
    [PMID:28507175]