PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA12G00161

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

NAC

Protein Properties

Length: 400aa MW: 45707.2 Da PI: 6.9557

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA12G00161	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	127.5	1.1e-39	10	118	20	128
NAM 20 kkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgelvglkktLvfykgrapkg 116 ++kv +k++++ ++i evdiyk+ePw+L +++k++++ewyfFs dkky +g r nrat++gyWkatgkd+e+ + + +l+g+kktLvf++grap+g AA12G00161 10 NRKVLSKPVRF-DAIGEVDIYKHEPWELAvySRLKTRDQEWYFFSALDKKYGNGARMNRATNKGYWKATGKDREIRR-DIQLIGMKKTLVFHSGRAPDG 106 68999999998.89************85448899999*********************************9.999************** PP NAM 117 ektdWvmheyrl 128 +t+Wvmheyrl AA12G00161 107 LRTNWVMHEYRL 118 ********98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS51005	44.317	1	142	IPR003441	NAC domain
SuperFamily	SSF101941	2.62E-45	11	143	IPR003441	NAC domain
Pfam	PF02365	1.4E-15	33	118	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 400 aa Download sequence Send to blast
MELKPKSKIN RKVLSKPVRF DAIGEVDIYK HEPWELAVYS RLKTRDQEWY FFSALDKKYG 60 NGARMNRATN KGYWKATGKD REIRRDIQLI GMKKTLVFHS GRAPDGLRTN WVMHEYRLVE 120 YDTEKNGGPQ QDAYVLCRVF HKNNIGPPSG NRYAPFMEEE WDDGGRAMIP GESVSFMANP 180 LLIKGDNDIH QENQSLNKNL ININELPRES QIENEPKQHQ NKPQENNNNN NEQENEESLK 240 RESPEEDGSP PLCVLNKEAP LPLLQYKRRR QNDSNNSSRT GTTQDHCSST TTVDTTTITS 300 SAATNTAISA LLEFSLMGCN EKKLQPTLKD NNKTDAIAAV FAANSSSIKL INDLQKENHQ 360 MVVERETFKL EMMSAEAMIS ILQSRIDALR QENEEMKKNG

Sequence ? help Back to Top

Protein Sequence Length: 400 aa Download sequence Send to blast

MELKPKSKIN RKVLSKPVRF DAIGEVDIYK HEPWELAVYS RLKTRDQEWY FFSALDKKYG  60
NGARMNRATN KGYWKATGKD REIRRDIQLI GMKKTLVFHS GRAPDGLRTN WVMHEYRLVE  120
YDTEKNGGPQ QDAYVLCRVF HKNNIGPPSG NRYAPFMEEE WDDGGRAMIP GESVSFMANP  180
LLIKGDNDIH QENQSLNKNL ININELPRES QIENEPKQHQ NKPQENNNNN NEQENEESLK  240
RESPEEDGSP PLCVLNKEAP LPLLQYKRRR QNDSNNSSRT GTTQDHCSST TTVDTTTITS  300
SAATNTAISA LLEFSLMGCN EKKLQPTLKD NNKTDAIAAV FAANSSSIKL INDLQKENHQ  360
MVVERETFKL EMMSAEAMIS ILQSRIDALR QENEEMKKNG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	7e-37	9	144	38	170	NAC domain-containing protein 19
3swm_B	7e-37	9	144	38	170	NAC domain-containing protein 19
3swm_C	7e-37	9	144	38	170	NAC domain-containing protein 19
3swm_D	7e-37	9	144	38	170	NAC domain-containing protein 19
3swp_A	7e-37	9	144	38	170	NAC domain-containing protein 19
3swp_B	7e-37	9	144	38	170	NAC domain-containing protein 19
3swp_C	7e-37	9	144	38	170	NAC domain-containing protein 19
3swp_D	7e-37	9	144	38	170	NAC domain-containing protein 19
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA12G00161

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010543579.1	0.0	PREDICTED: NAC domain-containing protein 4 isoform X1
Refseq	XP_010543580.1	0.0	PREDICTED: NAC domain-containing protein 4 isoform X2
Swissprot	Q9SQX9	0.0	NAC50_ARATH; NAC domain containing protein 50
TrEMBL	A0A397ZF44	0.0	A0A397ZF44_BRACM; Uncharacterized protein
STRING	XP_010543580.1	0.0	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1780	28	80

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10480.1	1e-169	NAC domain containing protein 50

Publications ? help Back to Top
Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990]