PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA19G00273

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

MYB_related

Protein Properties

Length: 709aa MW: 77550.6 Da PI: 5.4127

Description

MYB_related family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA19G00273	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Myb_DNA-binding	41.8	2.5e-13	49	93	1	47
TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHH CS Myb_DNA-binding 1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqky 47 r +WT eE++++++a +++ + Wk+I +g +t q++s+ qky AA19G00273 49 RESWTDEEHDKFLEALQLFDRD-WKKIEDFIG-SKTVIQIRSHAQKY 93 789***************77.*****.***********9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF46689	8.22E-17	43	99	IPR009057	Homeodomain-like
PROSITE profile	PS51294	15.475	44	98	IPR017930	Myb domain
Gene3D	G3DSA:1.10.10.60	7.7E-7	47	99	IPR009057	Homeodomain-like
TIGRFAMs	TIGR01557	7.7E-18	47	96	IPR006447	Myb domain, plants
SMART	SM00717	3.9E-11	48	96	IPR001005	SANT/Myb domain
Pfam	PF00249	1.0E-10	49	93	IPR001005	SANT/Myb domain
CDD	cd00167	3.26E-8	51	94	No hit	No description
Pfam	PF10018	3.3E-8	426	574	IPR019258	Mediator complex, subunit Med4

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006357	Biological Process	regulation of transcription from RNA polymerase II promoter
GO:0016592	Cellular Component	mediator complex
GO:0001104	Molecular Function	RNA polymerase II transcription cofactor activity
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 709 aa Download sequence Send to blast
MTSSPSSNSV VEELPTMIAS TDATETTITA AVEASDKKVR KPYTITKSRE SWTDEEHDKF 60 LEALQLFDRD WKKIEDFIGS KTVIQIRSHA QKYFLKVQKN GTLAHVPPPR PKRKAAHPYP 120 QKAPKNAQMS LQVSTSFPTR NNNAPGYTSW DDTSAFLDIA AIELLHLMKF HVLITAYNVI 180 VSVDIGSQGR TSASSPSASG IGSSSRTLPD SKILRQEKLA PVIHALPDFA EVYNFIGSVF 240 DPDSKGRMEK LKEMDPINFE TVLLLMRNLT VNLANPNFEP DMLQHQIVQS PARLGLTGPG 300 SPSVQNPTPP RHGHPTSSSS SQSQHQQIQQ PSNLLPSSIA ASSSASASAS AVISSSTLLS 360 LLPPLPRAQA LLQQIALLTS KLFDVSHNRS LWITAFRGTL PSFLSSHSLP PPPPLENPNP 420 STTKEILSRL NNLQTQLFDA VTELQEILDF QDAKQKVARE IKSKDSSLLA FANKLKEAEL 480 VLDMLVDDYS DYRKPKRCKA IGDSQEEENE DESSQSVSTT VSSQLKLKDI LAYAHKISYT 540 TFAPPEFGAG QAPLRGALPP APQDEQMRAS QLYTFADLDI GLPKMADNVE QKVATLVEPP 600 PPEPTNFSAL LPPNIAVPSG WKPGMPVELP KDLPLPPPGW KPGDPVVLPP FESMAAPRAE 660 EQHVAAMRPL PGLHRPPEVI QVRAVQLDIL EDDDSSDYSS DDGSSDDED

Sequence ? help Back to Top

Protein Sequence Length: 709 aa Download sequence Send to blast

MTSSPSSNSV VEELPTMIAS TDATETTITA AVEASDKKVR KPYTITKSRE SWTDEEHDKF  60
LEALQLFDRD WKKIEDFIGS KTVIQIRSHA QKYFLKVQKN GTLAHVPPPR PKRKAAHPYP  120
QKAPKNAQMS LQVSTSFPTR NNNAPGYTSW DDTSAFLDIA AIELLHLMKF HVLITAYNVI  180
VSVDIGSQGR TSASSPSASG IGSSSRTLPD SKILRQEKLA PVIHALPDFA EVYNFIGSVF  240
DPDSKGRMEK LKEMDPINFE TVLLLMRNLT VNLANPNFEP DMLQHQIVQS PARLGLTGPG  300
SPSVQNPTPP RHGHPTSSSS SQSQHQQIQQ PSNLLPSSIA ASSSASASAS AVISSSTLLS  360
LLPPLPRAQA LLQQIALLTS KLFDVSHNRS LWITAFRGTL PSFLSSHSLP PPPPLENPNP  420
STTKEILSRL NNLQTQLFDA VTELQEILDF QDAKQKVARE IKSKDSSLLA FANKLKEAEL  480
VLDMLVDDYS DYRKPKRCKA IGDSQEEENE DESSQSVSTT VSSQLKLKDI LAYAHKISYT  540
TFAPPEFGAG QAPLRGALPP APQDEQMRAS QLYTFADLDI GLPKMADNVE QKVATLVEPP  600
PPEPTNFSAL LPPNIAVPSG WKPGMPVELP KDLPLPPPGW KPGDPVVLPP FESMAAPRAE  660
EQHVAAMRPL PGLHRPPEVI QVRAVQLDIL EDDDSSDYSS DDGSSDDED

Functional Description ? help Back to Top
Source	Description
UniProt	Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). {ECO:0000250}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA19G00273

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010490754.1	1e-177	PREDICTED: mediator of RNA polymerase II transcription subunit 4
Swissprot	Q9LZ00	1e-169	MED4_ARATH; Mediator of RNA polymerase II transcription subunit 4
TrEMBL	A0A0D3EI91	0.0	A0A0D3EI91_BRAOL; Uncharacterized protein
TrEMBL	A0A3P6EQD7	0.0	A0A3P6EQD7_BRAOL; Uncharacterized protein
STRING	Bo9g183320.1	0.0	(Brassica oleracea)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM9487	4	4

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G02840.3	1e-100	LHY/CCA1-like 1

Publications ? help Back to Top
Mathur S,Vyas S,Kapoor S,Tyagi AK The Mediator complex in plants: structure, phylogeny, and expression profiling of representative genes in a dicot (Arabidopsis) and a monocot (rice) during reproduction and abiotic stress. Plant Physiol., 2011. 157(4): p. 1609-27 [PMID:22021418] Li W, et al. SAD1, an RNA polymerase I subunit A34.5 of rice, interacts with Mediator and controls various aspects of plant development. Plant J., 2015. 81(2): p. 282-91 [PMID:25404280]