PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA2G00186

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

AP2

Protein Properties

Length: 558aa MW: 61895.3 Da PI: 6.4774

Description

AP2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA2G00186	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	33.6	9.8e-11	184	240	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrd.pseng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 s y+GV++++++gr++A+++d + ++ k + g ++ +e+Aa+ ++ a++k++g AA2G00186 184 SIYRGVTRHRWTGRYEAHLWDnSCR-RegQSrKGRQ-GGYDKEEKAARSYDLAALKYWG 240 57*****************5444.2455536655.779999************98 PP
2	AP2	47.1	6.1e-15	285	334	3	55
AP2 3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 y+GV+++++ grW A+I + +k +lg+f t+eeAa+a++ a+ k++g AA2G00186 285 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSTEEEAAEAYDIAAIKFRG 334 9*************988532...5**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	6.54E-14	184	249	IPR016177	DNA-binding domain
CDD	cd00018	2.36E-18	184	250	No hit	No description
Pfam	PF00847	2.7E-8	184	240	IPR001471	AP2/ERF domain
SMART	SM00380	1.9E-22	185	254	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.8E-11	185	248	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	17.266	185	248	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	186	197	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	8.5E-18	283	343	IPR016177	DNA-binding domain
CDD	cd00018	3.93E-24	283	344	No hit	No description
SMART	SM00380	1.5E-32	284	348	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	19.506	284	342	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	4.6E-18	284	342	IPR001471	AP2/ERF domain
Pfam	PF00847	1.5E-9	285	334	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.9E-6	324	344	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 558 aa Download sequence Send to blast
MNSNNWLAFP LSSQSSQFNE NPFQNQEWNM INPHGGGDGG GGGEIPKVAD FLGVNKSENH 60 HHHHDEHNLV TTNNFNESSD YYFQTNSLLP TVHSSDEIVT CATTTTTPNN NNFEHLQESA 120 HNLQSLTLSM GNSGNNTLAI VKVASHGGDE EASADNSSSS TTNNSIVEAT PARRTLETFG 180 QRTSIYRGVT RHRWTGRYEA HLWDNSCRRE GQSRKGRQGG YDKEEKAARS YDLAALKYWG 240 PSTTTNFPIT NYEKEVEEMK HMTRQEFVAA IRRKSSGFSR GASMYRGVTR HHQHGRWQAR 300 IGRVAGNKDL YLGTFSTEEE AAEAYDIAAI KFRGLNAVTN FEINRYDVKA ILESNTLPIG 360 GGAAKRLKEA QALESSRKRE EMIALGSSSF HHHYGAPTTG DSSSSSSRLQ LQPYPLSIQQ 420 PFEHLHQQQP LLSLQNNNDQ ISQYSDYIQT QLHLHQQQQQ TNNYLQTSSL NQNSQLYNAY 480 LQSNPGFLHG FMSDNGANTA MFLGGNNGMS LGGNSTAPEE DFPAVKVDYD MNNSGGGYGG 540 WSNGEANPGG SVFTMWNE

Sequence ? help Back to Top

Protein Sequence Length: 558 aa Download sequence Send to blast

MNSNNWLAFP LSSQSSQFNE NPFQNQEWNM INPHGGGDGG GGGEIPKVAD FLGVNKSENH  60
HHHHDEHNLV TTNNFNESSD YYFQTNSLLP TVHSSDEIVT CATTTTTPNN NNFEHLQESA  120
HNLQSLTLSM GNSGNNTLAI VKVASHGGDE EASADNSSSS TTNNSIVEAT PARRTLETFG  180
QRTSIYRGVT RHRWTGRYEA HLWDNSCRRE GQSRKGRQGG YDKEEKAARS YDLAALKYWG  240
PSTTTNFPIT NYEKEVEEMK HMTRQEFVAA IRRKSSGFSR GASMYRGVTR HHQHGRWQAR  300
IGRVAGNKDL YLGTFSTEEE AAEAYDIAAI KFRGLNAVTN FEINRYDVKA ILESNTLPIG  360
GGAAKRLKEA QALESSRKRE EMIALGSSSF HHHYGAPTTG DSSSSSSRLQ LQPYPLSIQQ  420
PFEHLHQQQP LLSLQNNNDQ ISQYSDYIQT QLHLHQQQQQ TNNYLQTSSL NQNSQLYNAY  480
LQSNPGFLHG FMSDNGANTA MFLGGNNGMS LGGNSTAPEE DFPAVKVDYD MNNSGGGYGG  540
WSNGEANPGG SVFTMWNE

Functional Description ? help Back to Top
Source	Description
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Master regulator of basal/root fate. Essential for root quiescent center (QC) and columella specification, stem cell activity, as well as for establishment of the stem cell niche during embryogenesis. Modulates the root polar auxin transport by regulating the distribution of PIN genes. Essential role in respecifying pattern and polarity in damaged roots. Direct target of the transcriptional corepressor TPL. Expression levels and patterns regulated post-transcriptionally by root meristem growth factors (RGFs). {ECO:0000250, ECO:0000269\|PubMed:15454085, ECO:0000269\|PubMed:15635403, ECO:0000269\|PubMed:16424342, ECO:0000269\|PubMed:20190735}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA2G00186

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By auxin accumulation. {ECO:0000269\|PubMed:15454085}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010461951.1	0.0	PREDICTED: AP2-like ethylene-responsive transcription factor PLT2
Swissprot	Q5YGP7	0.0	PLET2_ARATH; AP2-like ethylene-responsive transcription factor PLT2
TrEMBL	R0GTX3	0.0	R0GTX3_9BRAS; Uncharacterized protein
STRING	XP_010461951.1	0.0	(Camelina sativa)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3015	27	67

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G51190.1	0.0	AP2 family protein

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Lee DK,Sieburth LE The bps signal: embryonic arrest from an auxin-independent mechanism in bypass triple mutants. Plant Signal Behav, 2012. 7(6): p. 698-700 [PMID:22580686] Hong LW,Yan DW,Liu WC,Chen HG,Lu YT TIME FOR COFFEE controls root meristem size by changes in auxin accumulation in Arabidopsis. J. Exp. Bot., 2014. 65(1): p. 275-86 [PMID:24277277] Tian H,Jia Y,Niu T,Yu Q,Ding Z The key players of the primary root growth and development also function in lateral roots in Arabidopsis. Plant Cell Rep., 2014. 33(5): p. 745-53 [PMID:24504658] Zhao Q, et al. Sulfur nutrient availability regulates root elongation by affecting root indole-3-acetic acid levels and the stem cell niche. J Integr Plant Biol, 2014. 56(12): p. 1151-63 [PMID:24831283] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Yang S, et al. The Arabidopsis SWI2/SNF2 Chromatin Remodeling ATPase BRAHMA Targets Directly to PINs and Is Required for Root Stem Cell Niche Maintenance. Plant Cell, 2015. 27(6): p. 1670-80 [PMID:25991732] Jia Y, et al. The Arabidopsis thaliana elongator complex subunit 2 epigenetically affects root development. J. Exp. Bot., 2015. 66(15): p. 4631-42 [PMID:25998905] Zhang M, et al. A tetratricopeptide repeat domain-containing protein SSR1 located in mitochondria is involved in root development and auxin polar transport in Arabidopsis. Plant J., 2015. 83(4): p. 582-99 [PMID:26072661] Shinohara H,Mori A,Yasue N,Sumida K,Matsubayashi Y Identification of three LRR-RKs involved in perception of root meristem growth factor in Arabidopsis. Proc. Natl. Acad. Sci. U.S.A., 2016. 113(14): p. 3897-902 [PMID:27001831] Ou Y, et al. RGF1 INSENSITIVE 1 to 5, a group of LRR receptor-like kinases, are essential for the perception of root meristem growth factor 1 in Arabidopsis thaliana. Cell Res., 2016. 26(6): p. 686-98 [PMID:27229312] Santuari L, et al. The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots. Plant Cell, 2016. 28(12): p. 2937-2951 [PMID:27920338] Promchuea S,Zhu Y,Chen Z,Zhang J,Gong Z ARF2 coordinates with PLETHORAs and PINs to orchestrate ABA-mediated root meristem activity in Arabidopsis . J Integr Plant Biol, 2017. 59(1): p. 30-43 [PMID:28074634] Du Y,Scheres B PLETHORA transcription factors orchestrate de novo organ patterning during Arabidopsis lateral root outgrowth. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(44): p. 11709-11714 [PMID:29078398] Bustillo-Avendaño E, et al. Regulation of Hormonal Control, Cell Reprogramming, and Patterning during De Novo Root Organogenesis. Plant Physiol., 2018. 176(2): p. 1709-1727 [PMID:29233938]