PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA33G00005

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

bHLH

Protein Properties

Length: 586aa MW: 66636 Da PI: 4.8269

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA33G00005	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.8	1.7e-12	327	370	7	55
HHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 7 erErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 +ErrRR+++N+++ Lr+l+P +Kl+ a+iL A++Y+k+Lq AA33G00005 327 LAERRRRKKLNDRLYALRSLVPRI-----TKLDRASILGDAINYVKELQ 370 68*******************7.....7****************9 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF14215	2.1E-18	10	149	IPR025610	Transcription factor MYC/MYB N-terminal
CDD	cd00083	3.59E-14	318	372	No hit	No description
PROSITE profile	PS50888	16.387	320	369	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	4.06E-17	323	385	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	4.7E-16	326	375	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	1.2E-16	327	383	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	4.3E-10	327	370	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009555	Biological Process	pollen development
GO:0048657	Biological Process	anther wall tapetum cell differentiation
GO:0005634	Cellular Component	nucleus
GO:0000978	Molecular Function	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 586 aa Download sequence Send to blast
MENSIQNLLE KLRPLVGSRA WDYCVLWRLN EDQRFVKWMG CCCGGTEVMI ENNGSEEFNF 60 GSCRDVMFHH PRTKSCEFLA HLPSSIPLDS GIYAETLLTN QTGWLSESSE PGFMQETICT 120 RVLIPIPGGL VELFVTRHVP EDQNVVDFVM GQCNILIDDQ TVNINMMVAA AADEVESKPY 180 GGLPNEIHER NSKVDEMMNL PSPYDISTDQ IRINFLPQMN DFESQQNQQL KMKSDYHQGL 240 GYLPENSNKE MGLNPFNTVT EDEIAVMANG GGMQQHVESG EPPSLQDVND KENENGRLDS 300 GSDCSDQIDD EDDTKCKKKT GQAKNLLAER RRRKKLNDRL YALRSLVPRI TKLDRASILG 360 DAINYVKELQ NESKELQDEL EENSETEDGC NRQGGMSLNG TVLTGAHSDF IKGLSCNSNV 420 PNLKQDLDLE NSNDKGQEME PQVDVAQLDG KEFFVKVICE YKPGGFTRLM EAMDSLGLEV 480 TNANTTRYLS LVSNVFKVEK KDGEMVQAEH VRNSLLDITR NTSRVWHDDH QMGTTSVQNE 540 VEYQQYDDHH HHDGHNHLHD HQMNPNIHHH HHHQQQHIHH NYHNQV

Sequence ? help Back to Top

Protein Sequence Length: 586 aa Download sequence Send to blast

MENSIQNLLE KLRPLVGSRA WDYCVLWRLN EDQRFVKWMG CCCGGTEVMI ENNGSEEFNF  60
GSCRDVMFHH PRTKSCEFLA HLPSSIPLDS GIYAETLLTN QTGWLSESSE PGFMQETICT  120
RVLIPIPGGL VELFVTRHVP EDQNVVDFVM GQCNILIDDQ TVNINMMVAA AADEVESKPY  180
GGLPNEIHER NSKVDEMMNL PSPYDISTDQ IRINFLPQMN DFESQQNQQL KMKSDYHQGL  240
GYLPENSNKE MGLNPFNTVT EDEIAVMANG GGMQQHVESG EPPSLQDVND KENENGRLDS  300
GSDCSDQIDD EDDTKCKKKT GQAKNLLAER RRRKKLNDRL YALRSLVPRI TKLDRASILG  360
DAINYVKELQ NESKELQDEL EENSETEDGC NRQGGMSLNG TVLTGAHSDF IKGLSCNSNV  420
PNLKQDLDLE NSNDKGQEME PQVDVAQLDG KEFFVKVICE YKPGGFTRLM EAMDSLGLEV  480
TNANTTRYLS LVSNVFKVEK KDGEMVQAEH VRNSLLDITR NTSRVWHDDH QMGTTSVQNE  540
VEYQQYDDHH HHDGHNHLHD HQMNPNIHHH HHHQQQHIHH NYHNQV

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	316	334	KKKTGQAKNLLAERRRRKK
2	328	335	ERRRRKKL

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a crucial role in tapetum development. Required for male fertility and pollen differentiation, especially during the post-meiotic transcriptional regulation of microspore development within the developing anther (PubMed:12535353). Binds E-box regions in the AHL16/TEK promoter. {ECO:0000269\|PubMed:12535353, ECO:0000269\|PubMed:24804694}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA33G00005

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006409372.1	0.0	transcription factor ABORTED MICROSPORES
Swissprot	Q9ZVX2	0.0	AMS_ARATH; Transcription factor ABORTED MICROSPORES
TrEMBL	V4LJU2	0.0	V4LJU2_EUTSA; Uncharacterized protein
STRING	XP_006409372.1	0.0	(Eutrema salsugineum)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM7589	27	41

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G16910.1	0.0	bHLH family protein

Publications ? help Back to Top
Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Jiang J,Zhang Z,Cao J Pollen wall development: the associated enzymes and metabolic pathways. Plant Biol (Stuttg), 2013. 15(2): p. 249-63 [PMID:23252839] Xu J, et al. ABORTED MICROSPORES Acts as a Master Regulator of Pollen Wall Formation in Arabidopsis. Plant Cell, 2014. 26(4): p. 1544-1556 [PMID:24781116] Qian H, et al. Trace concentrations of imazethapyr (IM) affect floral organs development and reproduction in Arabidopsis thaliana: IM-induced inhibition of key genes regulating anther and pollen biosynthesis. Ecotoxicology, 2015. 24(1): p. 163-71 [PMID:25348600] Xiong SX, et al. The transcription factors MS188 and AMS form a complex to activate the expression of CYP703A2 for sporopollenin biosynthesis in Arabidopsis thaliana. Plant J., 2016. 88(6): p. 936-946 [PMID:27460657] Ferguson AC, et al. Biphasic regulation of the transcription factor ABORTED MICROSPORES (AMS) is essential for tapetum and pollen development in Arabidopsis. New Phytol., 2017. 213(2): p. 778-790 [PMID:27787905] Lou Y, et al. Positive regulation of AMS by TDF1 and the formation of a TDF1-AMS complex are required for anther development in Arabidopsis thaliana. New Phytol., 2018. 217(1): p. 378-391 [PMID:28940573] Bi H,Fan W,Zhang P C4 Protein of Sweet Potato Leaf Curl Virus Regulates Brassinosteroid Signaling Pathway through Interaction with AtBIN2 and Affects Male Fertility in Arabidopsis. Front Plant Sci, 2017. 8: p. 1689 [PMID:29021807]