PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA39G00465
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family NAC
Protein Properties Length: 514aa    MW: 57589.1 Da    PI: 4.5097
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA39G00465genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM148.63.2e-4651262128
         NAM   2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp.k.kvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 
                 +pGfrFhPtdeel+v+yLk+k+ +kkl++ ++i e+d+yk++P+dLp k ++k+++++w+fFs rdkk        r t++gyWkatg+dkev++ +++
  AA39G00465   5 APGFRFHPTDEELIVYYLKRKICRKKLRV-NAIGETDVYKYDPQDLPgKaSYKSRDRQWFFFSLRDKKCG-----GRGTENGYWKATGNDKEVMC-NSR 96 
                 69***************************.89***************6347777999**********985.....68899***************.999 PP

         NAM  99 lvglkktLvfykgrapkgektdWvmheyrl 128
                 lvg++ktLvf++g+apkge+tdWvmhey+l
  AA39G00465  97 LVGMRKTLVFHRGKAPKGERTDWVMHEYSL 126
                 ****************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019417.19E-524150IPR003441NAC domain
PROSITE profilePS5100550.0784150IPR003441NAC domain
PfamPF023651.8E-256126IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010114Biological Processresponse to red light
GO:0010224Biological Processresponse to UV-B
GO:0031930Biological Processmitochondria-nucleus signaling pathway
GO:1900409Biological Processpositive regulation of cellular response to oxidative stress
GO:0005634Cellular Componentnucleus
GO:0005789Cellular Componentendoplasmic reticulum membrane
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 514 aa     Download sequence    Send to blast
MECIAPGFRF HPTDEELIVY YLKRKICRKK LRVNAIGETD VYKYDPQDLP GKASYKSRDR  60
QWFFFSLRDK KCGGRGTENG YWKATGNDKE VMCNSRLVGM RKTLVFHRGK APKGERTDWV  120
MHEYSLVEEE LKNLENVTKG YYVVNKVFKK SGSGPKNGAQ YGAPFIEEEW VDDDDDVEDV  180
IESADVDVSA NQLTVDNRLV NGLSQSELDG YDIEDLMRQV REEPSHVGDL VGPTLQLGEL  240
SGVESPVETF NPTNLSRDAY LEIDDLLLSG PEPGSVEAVP ENWDLDVSDD VENNRFFDVD  300
SYFLDMDAAD PNSSSDPQSE HVRIGLANGV EQQPASVTDQ ATNDQVQQQT VVNQASDWPL  360
AKNVAMSSRM WTQELNNDVL TDTQFVKKPL IVPGTGDASE SMNPLSDIST ANKDDSSQFT  420
SSLWDFLESI PASPAYASEN PFLNKTQLRT SSHGHVNVVV TVNNDLAAKS MKRRENNKIK  480
KNKSFFFLSI IGALCAVFWV CVGTVGFSRR FMLS
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
3ulx_A1e-37412615140Stress-induced transcription factor NAC1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5'-CTTGNNNNNCA[AC]G-3', a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance. {ECO:0000269|PubMed:24045019}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00176DAPTransfer from AT1G32870Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA39G00465
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By heat, salt stress, abscisic acid (ABA) and methyl methanesulfonate (MMS) treatment. {ECO:0000269|PubMed:17158162}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006416168.11e-169NAC domain-containing protein 13
SwissprotF4IED21e-149NAC13_ARATH; NAC domain-containing protein 13
TrEMBLV4MRY11e-168V4MRY1_EUTSA; Uncharacterized protein
STRINGBostr.3359s0074.1.p1e-170(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM153171517
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G32870.11e-133NAC domain protein 13
Publications ? help Back to Top
  1. Vermeirssen V,De Clercq I,Van Parys T,Van Breusegem F,Van de Peer Y
    Arabidopsis ensemble reverse-engineered gene regulatory network discloses interconnected transcription factors in oxidative stress.
    Plant Cell, 2014. 26(12): p. 4656-79
    [PMID:25549671]
  2. O'Shea C, et al.
    Structures and Short Linear Motif of Disordered Transcription Factor Regions Provide Clues to the Interactome of the Cellular Hub Protein Radical-induced Cell Death1.
    J. Biol. Chem., 2017. 292(2): p. 512-527
    [PMID:27881680]