PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA56G00080

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

WOX

Protein Properties

Length: 350aa MW: 38963.1 Da PI: 7.1

Description

WOX family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA56G00080	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	Homeobox	54	2.9e-17	60	120	2	57
T--SS--HHHHHHHHHHHHH.SSS--HHHHHHHHHHC....TS-HHHHHHHHHHHHHHHHC CS Homeobox 2 rkRttftkeqleeLeelFek.nrypsaeereeLAkkl....gLterqVkvWFqNrRakekk 57 ++R+++++eq+++Le+ F++ +p +ee++++ +l ++ +++V++WFqNr+ + k+ AA56G00080 60 KPRWNPKPEQIRILESIFNSgMINPPREEIKKIRIRLqefgQIGDANVFYWFQNRKSRAKH 120 89***************99***********************************995 PP
2	Wus_type_Homeobox	108.5	3.9e-35	59	121	2	64
Wus_type_Homeobox 2 artRWtPtpeQikiLeelyksGlrtPnkeeiqritaeLeeyGkiedkNVfyWFQNrkaRerqk 64 +++RW+P+peQi+iLe++++sG+ +P++eei++i+ +L+e+G+i+d+NVfyWFQNrk+R ++k AA56G00080 59 PKPRWNPKPEQIRILESIFNSGMINPPREEIKKIRIRLQEFGQIGDANVFYWFQNRKSRAKHK 121 579**********************************************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50071	10.203	56	121	IPR001356	Homeobox domain
SuperFamily	SSF46689	1.24E-11	58	125	IPR009057	Homeodomain-like
SMART	SM00389	4.5E-7	58	125	IPR001356	Homeobox domain
CDD	cd00086	2.23E-8	59	121	No hit	No description
Gene3D	G3DSA:1.10.10.60	2.4E-6	60	120	IPR009057	Homeodomain-like
Pfam	PF00046	7.0E-15	60	120	IPR001356	Homeobox domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0008284	Biological Process	positive regulation of cell proliferation
GO:0030010	Biological Process	establishment of cell polarity
GO:0048825	Biological Process	cotyledon development
GO:0090451	Biological Process	cotyledon boundary formation
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 350 aa Download sequence Send to blast
MSSSKKNWPS MFKSKPCNNH HHHHDMDTPS YMHYSNCNTS NSHFSAVNYY MITDRVPDPK 60 PRWNPKPEQI RILESIFNSG MINPPREEIK KIRIRLQEFG QIGDANVFYW FQNRKSRAKH 120 KLRVLQQKVP KISGLGPNKT NNHKEKHIAL SNDDVNPCFG LVNQETGLFP GQNNELVITE 180 PAGFPLPVYS DPRETQVGFG LVTEEGMGFN GVNNGVRLEM GESLTTIPAV NFYGGDNDGG 240 GSCYSPISVP VTVPLTVHQT QAPGDIVLYG GGDAGDCVSP VRLTVFINDM PFEVVAGLFN 300 VREAFGNDAV LINSSGEPIL TDEFGVTLQP LQNGAVYYLV RLFKRLQNLN

Sequence ? help Back to Top

Protein Sequence Length: 350 aa Download sequence Send to blast

MSSSKKNWPS MFKSKPCNNH HHHHDMDTPS YMHYSNCNTS NSHFSAVNYY MITDRVPDPK  60
PRWNPKPEQI RILESIFNSG MINPPREEIK KIRIRLQEFG QIGDANVFYW FQNRKSRAKH  120
KLRVLQQKVP KISGLGPNKT NNHKEKHIAL SNDDVNPCFG LVNQETGLFP GQNNELVITE  180
PAGFPLPVYS DPRETQVGFG LVTEEGMGFN GVNNGVRLEM GESLTTIPAV NFYGGDNDGG  240
GSCYSPISVP VTVPLTVHQT QAPGDIVLYG GGDAGDCVSP VRLTVFINDM PFEVVAGLFN  300
VREAFGNDAV LINSSGEPIL TDEFGVTLQP LQNGAVYYLV RLFKRLQNLN

Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor, which may be involved in embryonic patterning (PubMed:14711878). May be required for basal embryo development after fertilization (PubMed:14711878). Acts partially redundantly with STIP in promoting embryonic cell division and proliferation (PubMed:17706632). Promotes cotyledon boundary formation by maintaining the symmetry in CUC genes expression domains (PubMed:22827849). {ECO:0000269\|PubMed:17706632, ECO:0000269\|PubMed:22827849, ECO:0000303\|PubMed:14711878}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA56G00080

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated in the zygote after fertilization by the transcription factor WRKY2 (PubMed:21316593). Up-regulated by CLE8 (PubMed:22427333). {ECO:0000269\|PubMed:21316593, ECO:0000269\|PubMed:22427333}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_002865213.1	1e-159	WUSCHEL-related homeobox 8 isoform X1
Swissprot	Q6X7J5	1e-156	WOX8_ARATH; WUSCHEL-related homeobox 8
TrEMBL	D7MSP0	1e-158	D7MSP0_ARALL; Uncharacterized protein
STRING	scaffold_800245.1	1e-158	(Arabidopsis lyrata)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14262	16	19

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G45980.1	1e-159	WUSCHEL related homeobox 8

Publications ? help Back to Top
Xiao W, et al. DNA methylation is critical for Arabidopsis embryogenesis and seed viability. Plant Cell, 2006. 18(4): p. 805-14 [PMID:16531498] Wang W, et al. Dwarf Tiller1, a Wuschel-related homeobox transcription factor, is required for tiller growth in rice. PLoS Genet., 2014. 10(3): p. e1004154 [PMID:24625559] Zhu T,Moschou PN,Alvarez JM,Sohlberg JJ,von Arnold S Wuschel-related homeobox 8/9 is important for proper embryo patterning in the gymnosperm Norway spruce. J. Exp. Bot., 2014. 65(22): p. 6543-52 [PMID:25205582] Ueda M, et al. Transcriptional integration of paternal and maternal factors in the Arabidopsis zygote. Genes Dev., 2017. 31(6): p. 617-627 [PMID:28404632]