PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AA57G00277

Organism

Aethionema arabicum

Taxonomic ID

228871

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema

Family

LSD

Protein Properties

Length: 225aa MW: 24209.9 Da PI: 7.5454

Description

LSD family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AA57G00277	genome	VEGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-LSD1	34.7	3e-11	42	62	5	25
zf-LSD1 5 rtlLsYPrGApsVRCalCdtV 25 r++L YPrGA++V+CalC+t+ AA57G00277 42 RNILLYPRGATNVCCALCNTI 62 899****************97 PP
2	zf-LSD1	44.7	2.1e-14	85	109	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 CggCrt+L+Y rGA+sVRC++C+tV AA57G00277 85 CGGCRTMLMYSRGASSVRCSCCQTV 109 ************************9 PP
3	zf-LSD1	48.6	1.3e-15	147	171	1	25
zf-LSD1 1 CggCrtlLsYPrGApsVRCalCdtV 25 Cg+Crt+L+YP+GA+sV+Ca+C++V AA57G00277 147 CGHCRTTLMYPYGASSVKCAVCQFV 171 ***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
TIGRFAMs	TIGR01053	3.8E-9	42	65	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	8.0E-9	42	62	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	5.0E-18	82	112	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	3.2E-12	85	109	IPR005735	Zinc finger, LSD1-type
TIGRFAMs	TIGR01053	1.6E-13	144	174	IPR005735	Zinc finger, LSD1-type
Pfam	PF06943	7.6E-14	147	171	IPR005735	Zinc finger, LSD1-type

Sequence ? help Back to Top
Protein Sequence Length: 225 aa Download sequence Send to blast
LFRIESIPSP IEVFPGFDLD SGFGSKLSSI FLNPFEFQDK IRNILLYPRG ATNVCCALCN 60 TINVVPPPPP PPHVHGGMDM AHIICGGCRT MLMYSRGASS VRCSCCQTVN LVPGNKCSVE 120 LHYLLLMFDF SCYLSAAPSN QVAHINCGHC RTTLMYPYGA SSVKCAVCQF VTNVNMSNGR 180 VPIPLNRPNG TASPGTMPST STQSTPPSQT QTVVVENPMS VDESG

Functional Description ? help Back to Top
Source	Description
UniProt	Negative regulator of reactive oxygen-induced cell death, cold stress-induced cell death, pathogen-induced hypersensitive response (HR), basal disease resistance. May be involved in the induction of the copper/zinc superoxide dismutase CSD1 and CSD2 that detoxify accumulating superoxide before the reactive oxygen species (ROS) can trigger a cell death cascade. LSD1 and LOL1 have antagonistic effects on CSD1 and CSD2 accumulation to regulate oxidative stress-induced cell death. Antagonizes the function of BZIP10, a positive regulator of cell death, by interacting in the cytoplasm and preventing its nuclear localization. Controls lysigenous aerenchyma in hypocotyls under root hypoxia. Required for leaf acclimation in response to excess excitation energy. {ECO:0000269\|PubMed:10550898, ECO:0000269\|PubMed:11595797, ECO:0000269\|PubMed:11844114, ECO:0000269\|PubMed:12732715, ECO:0000269\|PubMed:15347794, ECO:0000269\|PubMed:16957775, ECO:0000269\|PubMed:18055613, ECO:0000269\|PubMed:18790826, ECO:0000269\|PubMed:20456049, ECO:0000269\|PubMed:21097903}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AA57G00277

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By methyl viologen. {ECO:0000269\|PubMed:20456049}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010538649.1	3e-89	PREDICTED: protein LSD1-like isoform X4
Swissprot	P94077	1e-70	LSD1_ARATH; Protein LSD1
TrEMBL	A0A3N6SID8	5e-86	A0A3N6SID8_BRACR; Uncharacterized protein
STRING	XP_010538646.1	1e-85	(Tarenaya hassleriana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM5345	26	50

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT4G20380.7	3e-69	LSD family protein

Publications ? help Back to Top
Spedaletti V, et al. Characterization of a lysine-specific histone demethylase from Arabidopsis thaliana. Biochemistry, 2008. 47(17): p. 4936-47 [PMID:18393445] Szechyńska-Hebda M,Czarnocka W,Hebda M,Bernacki MJ,Karpiński S PAD4, LSD1 and EDS1 regulate drought tolerance, plant biomass production, and cell wall properties. Plant Cell Rep., 2016. 35(3): p. 527-39 [PMID:26754794] Czarnocka W, et al. The dual role of LESION SIMULATING DISEASE 1 as a condition-dependent scaffold protein and transcription regulator. Plant Cell Environ., 2017. 40(11): p. 2644-2662 [PMID:28555890] Bernacki MJ, et al. LSD1-, EDS1- and PAD4-dependent conditional correlation among salicylic acid, hydrogen peroxide, water use efficiency and seed yield in Arabidopsis thaliana. Physiol Plant, 2019. 165(2): p. 369-382 [PMID:30461017]