PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA5G00216
Organism
Aethionema arabicum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family MIKC_MADS
Protein Properties Length: 245aa    MW: 28940.8 Da    PI: 6.7898
Description MIKC_MADS family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA5G00216genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1SRF-TF81.45.8e-26959151
               S---SHHHHHHHHHHHHHHHHHHHHHHHHHHT-EEEEEEE-TTSEEEEEE- CS
     SRF-TF  1 krienksnrqvtfskRrngilKKAeELSvLCdaevaviifsstgklyeyss 51
               k+ien++ rqvtfskRr+g++KK +ELSvLCda + +i+fs tgkl ey+s
  AA5G00216  9 KKIENQTARQVTFSKRRTGLIKKTHELSVLCDAHIGLIVFSATGKLSEYCS 59
               68***********************************************96 PP
2K-box61.82.8e-21851701398
      K-box  13 kaeslqqelakLkkeienLqreqRhllGedLesLslkeLqqLeqqLekslkkiRskKnellleqieelqkkekelqeenkaLrkkl 98 
                + e+l++e++ L++++ +L+  +R + G dL+s+   eL   eqqLe+s+ k+R++Knel+ +q+e+l +k ++l+een+++ + l
  AA5G00216  85 DREQLYNEISCLRRNTCELELRLRPFYGHDLTSIPPHELDGFEQQLENSVLKVRERKNELMQQQLENLSRKRRMLEEENNNMYRWL 170
                56899***************************************************************************987765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5006630.109161IPR002100Transcription factor, MADS-box
SMARTSM004325.0E-39160IPR002100Transcription factor, MADS-box
CDDcd002655.74E-43279No hitNo description
SuperFamilySSF554554.58E-31291IPR002100Transcription factor, MADS-box
PRINTSPR004043.0E-27323IPR002100Transcription factor, MADS-box
PROSITE patternPS003500357IPR002100Transcription factor, MADS-box
PfamPF003191.6E-231057IPR002100Transcription factor, MADS-box
PRINTSPR004043.0E-272338IPR002100Transcription factor, MADS-box
PRINTSPR004043.0E-273859IPR002100Transcription factor, MADS-box
PfamPF014864.6E-2084170IPR002487Transcription factor, K-box
PROSITE profilePS5129713.85986176IPR002487Transcription factor, K-box
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008360Biological Processregulation of cell shape
GO:0019252Biological Processstarch biosynthetic process
GO:0043068Biological Processpositive regulation of programmed cell death
GO:0048316Biological Processseed development
GO:0048481Biological Processplant ovule development
GO:0080155Biological Processregulation of double fertilization forming a zygote and endosperm
GO:2000029Biological Processregulation of proanthocyanidin biosynthetic process
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 245 aa     Download sequence    Send to blast
MGRGKIEIKK IENQTARQVT FSKRRTGLIK KTHELSVLCD AHIGLIVFSA TGKLSEYCSE  60
PIRMEQLVDR YLKTRGVQLP DPRDDREQLY NEISCLRRNT CELELRLRPF YGHDLTSIPP  120
HELDGFEQQL ENSVLKVRER KNELMQQQLE NLSRKRRMLE EENNNMYRWL QEQRAAIEYQ  180
QTGMEPKPGD YQQYLDQFQL FNNVQNQTQP NSVLQLATLQ SHEIIDPYHL QLAQPNLQND  240
LTKID
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5f28_A1e-16171169MEF2C
5f28_B1e-16171169MEF2C
5f28_C1e-16171169MEF2C
5f28_D1e-16171169MEF2C
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1152157SRKRRM
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the developmental regulation of the endothelium and in the accumulation of proanthocyanidins (PAs) or condensed tannins which give the seed its brown pigmentation after oxidation (PubMed:12368498, PubMed:16080001). Necessary for the normal activation of the BANYULS promoter in the endothelium body (PubMed:12368498). Is required, together with AGL11/STK for the maternal control of endothelium formation, which is essential for female gametophyte development and fertilization, and seed formation (PubMed:22176531). Interacts genetically with AGL1/SHP1 and AGL5/SHP2 in a partially antagonistic manner and represses AGL1/SHP1, AGL5/SHP2, and AGL8/FUL during flower development. Is essential for the coordination of cell divisions in ovule, seed coat development and endosperm formation (PubMed:27776173). Mediates the crosstalk between endothelium and nucellus to ensure proper seed formation. Functions redundantly with AGL63/GOA to repress nucellus growth and promote its degeneration. Represses the negative regulator of autophagy and programmed cell death HVA22D in the proximal nucellus (PubMed:27233529). Binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3' (PubMed:16080001). {ECO:0000269|PubMed:12368498, ECO:0000269|PubMed:16080001, ECO:0000269|PubMed:22176531, ECO:0000269|PubMed:27233529, ECO:0000269|PubMed:27776173}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA5G00216
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024007382.11e-133protein TRANSPARENT TESTA 16 isoform X1
RefseqXP_024007383.11e-133protein TRANSPARENT TESTA 16 isoform X2
SwissprotQ8RYD91e-127TT16_ARATH; Protein TRANSPARENT TESTA 16
TrEMBLA0A3Q8AGZ81e-175A0A3Q8AGZ8_9BRAS; MADS-box transcription factor AGL32 (Fragment)
STRINGBo7g097810.11e-128(Brassica oleracea)
STRINGBostr.10199s0104.1.p1e-128(Boechera stricta)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM65062543
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G23260.21e-130MIKC_MADS family protein
Publications ? help Back to Top
  1. Kim K,Jiang K,Teng SL,Feldman LJ,Huang H
    Using biologically interrelated experiments to identify pathway genes in Arabidopsis.
    Bioinformatics, 2012. 28(6): p. 815-22
    [PMID:22271267]
  2. Rhodes DH, et al.
    Genome-wide association study of grain polyphenol concentrations in global sorghum [Sorghum bicolor (L.) Moench] germplasm.
    J. Agric. Food Chem., 2014. 62(45): p. 10916-27
    [PMID:25272193]
  3. Xu W, et al.
    Endosperm and Nucellus Develop Antagonistically in Arabidopsis Seeds.
    Plant Cell, 2016. 28(6): p. 1343-60
    [PMID:27233529]
  4. Ehlers K, et al.
    The MADS Box Genes ABS, SHP1, and SHP2 Are Essential for the Coordination of Cell Divisions in Ovule and Seed Coat Development and for Endosperm Formation in Arabidopsis thaliana.
    PLoS ONE, 2016. 11(10): p. e0165075
    [PMID:27776173]
  5. Coen O, et al.
    Developmental patterning of the sub-epidermal integument cell layer in Arabidopsis seeds.
    Development, 2017. 144(8): p. 1490-1497
    [PMID:28348169]
  6. Xu W, et al.
    TRANSPARENT TESTA 16 and 15 act through different mechanisms to control proanthocyanidin accumulation in Arabidopsis testa.
    J. Exp. Bot., 2017. 68(11): p. 2859-2870
    [PMID:28830101]
  7. Fiume E,Coen O,Xu W,Lepiniec L,Magnani E
    Developmental patterning of sub-epidermal cells in the outer integument of Arabidopsis seeds.
    PLoS ONE, 2017. 12(11): p. e0188148
    [PMID:29141031]