PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AHYPO_018809-RA
Organism
Amaranthus hypochondriacus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Amaranthaceae; Amaranthus
Family C2H2
Protein Properties Length: 355aa    MW: 40868.3 Da    PI: 6.1086
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AHYPO_018809-RAgenomeBYUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.000476385323
                     ET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                     C+   Cgk+F +   L++H   H
  AHYPO_018809-RA 63 CSyeGCGKTFIDAGALRKHSHIH 85
                     77779**************7766 PP
2zf-C2H216.62.3e-0590114123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      y+C+   Cgk F ++s LkrH   H
  AHYPO_018809-RA  90 YVCHyeGCGKKFLDSSKLKRHFLIH 114
                      9********************8877 PP
3zf-C2H220.81e-06120144123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + Cp   Cgk Fs   nL++H++tH
  AHYPO_018809-RA 120 FICPheGCGKAFSLDFNLRSHMKTH 144
                      78**********************9 PP
4zf-C2H217.89.4e-06150174123
                      EEET..TTTEEESSHHHHHHHHHHT CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                      + Cp  dCgk++ + + Lk+Hi++H
  AHYPO_018809-RA 150 HICPyaDCGKRYAHEYKLKNHISMH 174
                      68**********************6 PP
5zf-C2H216.13.1e-05211236123
                      EEET..TTTEEESSHHHHHHHHHH.T CS
          zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                      y+Cp   C+k + + + L+ H+r+ H
  AHYPO_018809-RA 211 YTCPyeGCDKAYIHEYKLNLHLRReH 236
                      9**********************999 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.608.6E-145687IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.7836190IPR007087Zinc finger, C2H2
SMARTSM003550.00326185IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002806385IPR007087Zinc finger, C2H2
SuperFamilySSF576672.22E-864114No hitNo description
Gene3DG3DSA:3.30.160.602.2E-1488110IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.92190119IPR007087Zinc finger, C2H2
SMARTSM003550.002490114IPR015880Zinc finger, C2H2-like
PROSITE patternPS00028092114IPR007087Zinc finger, C2H2
SuperFamilySSF576673.29E-14101154No hitNo description
Gene3DG3DSA:3.30.160.605.6E-20111144IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.591120149IPR007087Zinc finger, C2H2
SMARTSM003553.9E-4120144IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280122144IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.2E-8145176IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0064150174IPR015880Zinc finger, C2H2-like
PROSITE profilePS501579.702150179IPR007087Zinc finger, C2H2
PROSITE patternPS000280152175IPR007087Zinc finger, C2H2
SuperFamilySSF576677.64E-6206234No hitNo description
Gene3DG3DSA:3.30.160.601.2E-8209234IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.014211241IPR007087Zinc finger, C2H2
SMARTSM003550.0019211236IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280213236IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045892Biological Processnegative regulation of transcription, DNA-templated
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 355 aa     Download sequence    Send to blast
YSHFAYGQFK LSITATELFQ FLESSFLFVT FLESALRTLK EKTKESEVLE PEPEPTTEVL  60
FLCSYEGCGK TFIDAGALRK HSHIHGERQY VCHYEGCGKK FLDSSKLKRH FLIHTGERDF  120
ICPHEGCGKA FSLDFNLRSH MKTHSQENYH ICPYADCGKR YAHEYKLKNH ISMHHEKNSG  180
EIAKYTPPVE KPVKTPKPVS AAFSASSDRP YTCPYEGCDK AYIHEYKLNL HLRREHPGHY  240
AEENAKTTQP NNADNEMDEG SDQEAYATKR STLKNMKQSR PKPNIKLPPS KMSQRKGSGV  300
SPANLNVVKK AWPIKEDVYE EDSEETEEDR DNDEDGWRYQ ENNEDDDEET EYED*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C5e-35541742117PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010670022.11e-177PREDICTED: uncharacterized zinc finger protein At4g06634 isoform X2
SwissprotQ2V3L31e-128YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A2Z7BGM61e-162A0A2Z7BGM6_9LAMI; Uncharacterized protein
STRINGXP_010670021.11e-174(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.21e-117C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]