PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G25310.1
Common NameBHLH108, EN132, F4F7.30, MEE8
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 145aa    MW: 17020.4 Da    PI: 9.6551
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G25310.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH16.61.5e-0575111950
                  HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHH CS
          HLH   9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveY 50 
                   ++RR+ri+  +e+L+e+ P++   p+      +iL  ++eY
  AT1G25310.1  75 KKKRRERIRRQLETLKEITPNC---PQSD--INAILDCVIEY 111
                  59*******************8...3333..33677777776 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088811.26166115IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.4E-667119IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474595.1E-770119IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009793Biological Processembryo development ending in seed dormancy
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 145 aa     Download sequence    Send to blast
MNKDEVFLRQ WFEILYSLTN PEANSDLRRI NNEKGVEKVG QKRSAESRRE GKKKRVKTQC  60
VIKSSDKSDH DTLLKKKRRE RIRRQLETLK EITPNCPQSD INAILDCVIE YTNNLRLAHY  120
KGSQGICDDW RLFTEAGAVL YYIDT
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
17478KKKRR
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO183956380.0
Expression AtlasAT1G25310-
AtGenExpressAT1G25310-
Functional Description ? help Back to Top
Source Description
UniProtRequired during early embryo development, for the endosperm formation. {ECO:0000269|PubMed:15634699}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G25310.1
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G25310
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0793741e-124AC079374.4 Arabidopsis thaliana chromosome 1 BAC F4F7 genomic sequence, complete sequence.
GenBankCP0026841e-124CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_173902.11e-104basic helix-loop-helix (bHLH) DNA-binding family protein
SwissprotQ9FRI01e-105MEE8_ARATH; Transcription factor MEE8
TrEMBLA0A178W8716e-70A0A178W871_ARATH; MEE8
STRINGAT1G25310.11e-104(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM1706168
Publications ? help Back to Top
  1. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  2. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  3. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  4. Pagnussat GC, et al.
    Genetic and molecular identification of genes required for female gametophyte development and function in Arabidopsis.
    Development, 2005. 132(3): p. 603-14
    [PMID:15634699]
  5. Cho EJ, et al.
    Protein disulfide isomerase-2 of Arabidopsis mediates protein folding and localizes to both the secretory pathway and nucleus, where it interacts with maternal effect embryo arrest factor.
    Mol. Cells, 2011. 32(5): p. 459-75
    [PMID:21909944]