PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G44830.1

Common Name

ERF014, T12C22.10

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 211aa MW: 23039.4 Da PI: 5.2437

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G44830.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	58.3	1.9e-18	33	83	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 ++ykGVr ++ +g+Wv+eIr p ++++r++lg++ tae Aa+a++aa ++l+g AT1G44830.1 33 KKYKGVRMRS-WGSWVSEIRAP---NQKTRIWLGSYSTAEAAARAYDAALLCLKG 83 59***998.******9...336**********************998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.08E-17	33	93	No hit	No description
Gene3D	G3DSA:3.30.730.10	5.5E-29	34	93	IPR001471	AP2/ERF domain
Pfam	PF00847	1.7E-11	34	83	IPR001471	AP2/ERF domain
SMART	SM00380	2.0E-32	34	98	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	21.759	34	92	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	3.99E-18	34	92	IPR016177	DNA-binding domain
PRINTS	PR00367	4.7E-9	35	46	IPR001471	AP2/ERF domain
PRINTS	PR00367	4.7E-9	57	73	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009861	Biological Process	jasmonic acid and ethylene-dependent systemic resistance
GO:0009863	Biological Process	salicylic acid mediated signaling pathway
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0045088	Biological Process	regulation of innate immune response
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:1900030	Biological Process	regulation of pectin biosynthetic process
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000026	anatomy	primary root tip
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0003015	anatomy	primary root differentiation zone
PO:0003022	anatomy	lateral root cap of primary root
PO:0005679	anatomy	epidermis
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009009	anatomy	plant embryo
PO:0009010	anatomy	seed
PO:0009025	anatomy	vascular leaf
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009052	anatomy	flower pedicel
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025257	anatomy	primary root elongation zone
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0001078	developmental stage	plant embryo cotyledonary stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 211 aa Download sequence Send to blast
MVKTLQKTPK RMSSPSSSSS SSSSTSSSSI RMKKYKGVRM RSWGSWVSEI RAPNQKTRIW 60 LGSYSTAEAA ARAYDAALLC LKGSSANNLN FPEISTSLYH IINNGDNNND MSPKSIQRVA 120 AAAAAANTDP SSSSVSTSSP LLSSPSEDLY DVVSMSQYDQ QVSLSESSSW YNCFDGDDQF 180 MFINGVSAPY LTTSLSDDFF EEGDIRLWNF C

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	6e-13	34	93	14	73	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	145336462	0.0
Genevisible	261327_at	0.0
Expression Atlas	AT1G44830	-
AtGenExpress	AT1G44830	-
ATTED-II	AT1G44830	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10.
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
Overexpression of the ERF gene coordinately activates the pectin biosynthetic pathway genes and increases the content of pectin. [PMID: 22160296] Data demonstrates that AtERF014 acts as a dual regulator that differentially modulates immunity against Pst and Bc in Arabidopsis. [AtERF014] [PMID: 27445230]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00185	DAP	27203113	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G44830.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G44830

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AY560839	0.0	AY560839.1 Arabidopsis thaliana putative AP2/EREBP transcription factor (At1g44830) mRNA, complete cds.
GenBank	BT025270	0.0	BT025270.1 Arabidopsis thaliana At1g44830 mRNA, complete cds.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
GenBank	T12C22	0.0	AC020576.2 Sequence of BAC T12C22 from Arabidopsis thaliana chromosome 1, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_175104.1	1e-152	Integrase-type DNA-binding superfamily protein
Swissprot	Q9LPE8	1e-153	ERF14_ARATH; Ethylene-responsive transcription factor ERF014
TrEMBL	A0A178WK18	1e-151	A0A178WK18_ARATH; Uncharacterized protein
STRING	AT1G44830.1	1e-152	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM14409	18	22
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT1G44830.1
Entrez Gene	841047
iHOP	AT1G44830
wikigenes	AT1G44830

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Ko JH,Han KH,Park S,Yang J Plant body weight-induced secondary growth in Arabidopsis and its transcription phenotype revealed by whole-transcriptome profiling. Plant Physiol., 2004. 135(2): p. 1069-83 [PMID:15194820] Guan Y,Nothnagel EA Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures. Plant Physiol., 2004. 135(3): p. 1346-66 [PMID:15235117] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Ma S,Gong Q,Bohnert HJ Dissecting salt stress pathways. J. Exp. Bot., 2006. 57(5): p. 1097-107 [PMID:16510518] Lee JY, et al. Transcriptional and posttranscriptional regulation of transcription factor expression in Arabidopsis roots. Proc. Natl. Acad. Sci. U.S.A., 2006. 103(15): p. 6055-60 [PMID:16581911] Brodersen P, et al. Arabidopsis MAP kinase 4 regulates salicylic acid- and jasmonic acid/ethylene-dependent responses via EDS1 and PAD4. Plant J., 2006. 47(4): p. 532-46 [PMID:16813576] Mace DL, et al. Quantification of transcription factor expression from Arabidopsis images. Bioinformatics, 2006. 22(14): p. e323-31 [PMID:16873489] Jiang Y,Deyholos MK Comprehensive transcriptional profiling of NaCl-stressed Arabidopsis roots reveals novel classes of responsive genes. BMC Plant Biol., 2006. 6: p. 25 [PMID:17038189] Culligan KM,Robertson CE,Foreman J,Doerner P,Britt AB ATR and ATM play both distinct and additive roles in response to ionizing radiation. Plant J., 2006. 48(6): p. 947-61 [PMID:17227549] Nakano T, et al. Increase in pectin deposition by overexpression of an ERF gene in cultured cells of Arabidopsis thaliana. Biotechnol. Lett., 2012. 34(4): p. 763-9 [PMID:22160296] Zhang H,Hong Y,Huang L,Li D,Song F Arabidopsis AtERF014 acts as a dual regulator that differentially modulates immunity against Pseudomonas syringae pv. tomato and Botrytis cinerea. Sci Rep, 2016. 6: p. 30251 [PMID:27445230]