PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G66140.1

Common Name

F15E12.19, ZFP4

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

C2H2

Protein Properties

Length: 260aa MW: 28308.5 Da PI: 6.6703

Description

zinc finger protein 4

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G66140.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	13.6	0.0002	85	107	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C + F ++ L H++ H AT1G66140.1 85 FSCNYCQRKFYSSQALGGHQNAH 107 89*****************9988 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF57667	1.06E-6	81	112	No hit	No description
PROSITE profile	PS50157	11.427	85	112	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	87	107	IPR007087	Zinc finger, C2H2

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0008270	Molecular Function	zinc ion binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000013	anatomy	cauline leaf
PO:0000037	anatomy	shoot apex
PO:0000230	anatomy	inflorescence meristem
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009006	anatomy	shoot system
PO:0009025	anatomy	vascular leaf
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0001054	developmental stage	vascular leaf senescent stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage

Sequence ? help Back to Top
Protein Sequence Length: 260 aa Download sequence Send to blast
MRPILDLEIE ASSGSSSSQV ASNLSPVGED YKPISLNLSL SFNNNNNNNL DLESSSLTLP 60 LSSTSESSNP EQQQQQQPSV SKRVFSCNYC QRKFYSSQAL GGHQNAHKRE RTLAKRAMRM 120 GLAGVFPGRG SSSNYAAAAT AAALSCLPLH GSGNGNMTSF RTLGIRAHSS AHDVSMTRQT 180 PETLIRNIAR FNQGYFGNCI PFYVEDDEAE MLWPGSFRQA TNAVAVEAGN DNLGERKMDF 240 LDVKQAMDME SSLPDLTLKL

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.25527	0.0	flower\| root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	256528_at	0.0
Expression Atlas	AT1G66140	-
AtGenExpress	AT1G66140	-
ATTED-II	AT1G66140	-

Functional Description ? help Back to Top
Source	Description
TAIR	Encodes a zinc finger protein containing only a single zinc finger.
UniProt	Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development. {ECO:0000269\|PubMed:24808098}.

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G66140.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G66140

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC026480	0.0	AC026480.6 Arabidopsis thaliana chromosome 1 BAC F15E12 genomic sequence, complete sequence.
GenBank	AF361630	0.0	AF361630.1 Arabidopsis thaliana At1g66140/F15E12_19 mRNA, complete cds.
GenBank	AK230229	0.0	AK230229.1 Arabidopsis thaliana mRNA for zinc finger protein ZFP4, complete cds, clone: RAFL23-05-K17.
GenBank	AK230232	0.0	AK230232.1 Arabidopsis thaliana mRNA for zinc finger protein ZFP4, complete cds, clone: RAFL23-06-L22.
GenBank	AK230250	0.0	AK230250.1 Arabidopsis thaliana mRNA for zinc finger protein ZFP4, complete cds, clone: RAFL23-17-O17.
GenBank	AY056067	0.0	AY056067.1 Arabidopsis thaliana At1g66140/F15E12_19 mRNA, complete cds.
GenBank	AY058087	0.0	AY058087.1 Arabidopsis thaliana At1g66140/F15E12_19 mRNA, complete cds.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_176788.1	0.0	zinc finger protein 4
Swissprot	Q39263	0.0	ZFP4_ARATH; Zinc finger protein 4
TrEMBL	A0A178W8F5	0.0	A0A178W8F5_ARATH; ZFP4
STRING	AT1G66140.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM6672	26	43
Representative plant	OGRP82	15	137

Link Out ? help Back to Top
Phytozome	AT1G66140.1
Entrez Gene	842928
iHOP	AT1G66140
wikigenes	AT1G66140

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Schenk PM, et al. Systemic gene expression in Arabidopsis during an incompatible interaction with Alternaria brassicicola. Plant Physiol., 2003. 132(2): p. 999-1010 [PMID:12805628] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Meister RJ, et al. Definition and interactions of a positive regulatory element of the Arabidopsis INNER NO OUTER promoter. Plant J., 2004. 37(3): p. 426-38 [PMID:14731261] Englbrecht CC,Schoof H,B Conservation, diversification and expansion of C2H2 zinc finger proteins in the Arabidopsis thaliana genome. BMC Genomics, 2004. 5(1): p. 39 [PMID:15236668] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Cao D,Cheng H,Wu W,Soo HM,Peng J Gibberellin mobilizes distinct DELLA-dependent transcriptomes to regulate seed germination and floral development in Arabidopsis. Plant Physiol., 2006. 142(2): p. 509-25 [PMID:16920880] Gaudinier A, et al. Enhanced Y1H assays for Arabidopsis. Nat. Methods, 2011. 8(12): p. 1053-5 [PMID:22037706] Causier B,Ashworth M,Guo W,Davies B The TOPLESS interactome: a framework for gene repression in Arabidopsis. Plant Physiol., 2012. 158(1): p. 423-38 [PMID:22065421] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Joseph MP, et al. The Arabidopsis ZINC FINGER PROTEIN3 Interferes with Abscisic Acid and Light Signaling in Seed Germination and Plant Development. Plant Physiol., 2014. 165(3): p. 1203-1220 [PMID:24808098] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Tague BW,Goodman HM Characterization of a family of Arabidopsis zinc finger protein cDNAs. Plant Mol. Biol., 1995. 28(2): p. 267-79 [PMID:7599312]