PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G66600.1
Common NameABO3, ATWRKY63, T12I7.5, WRKY63
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family WRKY
Protein Properties Length: 241aa    MW: 27378.8 Da    PI: 5.8839
Description ABA overly sensitive mutant 3
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G66600.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY67.91.5e-21102163159
                  ---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS- CS
         WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnhe 59 
                  ldDg++WrKYGqK++k s + r YYrC++a   +C ++k+v+  ++ p v  +tY g+H+++
  AT1G66600.1 102 LDDGFTWRKYGQKTIKTSLYQRCYYRCAYAkdqNCYATKRVQMIQDSPPVYRTTYLGQHTCK 163
                  59***************************98999**************************97 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5081118.37297165IPR003657WRKY domain
Gene3DG3DSA:2.20.25.803.0E-22100163IPR003657WRKY domain
SuperFamilySSF1182902.88E-23100163IPR003657WRKY domain
SMARTSM007741.3E-33102164IPR003657WRKY domain
PfamPF031061.4E-22103163IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009738Biological Processabscisic acid-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000003anatomywhole plant
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009025anatomyvascular leaf
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0007131developmental stageseedling development stage
Sequence ? help Back to Top
Protein Sequence    Length: 241 aa     Download sequence    Send to blast
MFSNIDHKAV AALLHGQGCA NILKTVLDNC KVSSVSTEPL INTILDSFSL ALSSVNSPNR  60
QPHHESSSRD MAGLVPQRSS KKKICGVKGL EIYRDDSPNP RLDDGFTWRK YGQKTIKTSL  120
YQRCYYRCAY AKDQNCYATK RVQMIQDSPP VYRTTYLGQH TCKAFGVHDN TYGSEMINFD  180
QVVSESVMRQ LATIGEQAVL MEDEANHIMN QEYDINDYLV DDEVFWGNEF PLFSSEDLML  240
F
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
6ir8_A1e-16102163869OsWRKY45
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.283250.0leaf
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible256364_at3e-51
Expression AtlasAT1G66600-
AtGenExpressAT1G66600-
Functional Description ? help Back to Top
Source Description
TAIRA member of WRKY Transcription Factor; Group III. Involved in the regulation of plant responses to ABA and drought stress.
UniProtTranscription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. AtWRKY40 and AtWRKY63 are particularly involved in regulating the expression of genes responding commonly to both mitochondrial and chloroplast dysfunction but not of genes responding to either mitochondrial or chloroplast perturbation.
    [PMID: 23509177]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00066PBM25215497Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G66600.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT2G14610(R)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDabscisic acid
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G66600
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4521720.0AF452172.1 Arabidopsis thaliana WRKY transcription factor 63 (WRKY63) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_176833.10.0ABA overly sensitive mutant 3
SwissprotQ9C6H50.0WRK63_ARATH; Probable WRKY transcription factor 63
TrEMBLA0A384L7K90.0A0A384L7K9_ARATH; WRKY63
TrEMBLC0SV190.0C0SV19_ARATH; Uncharacterized protein At1g66600 (Fragment)
STRINGAT1G66600.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM56091847
Representative plantOGRP1417875
Publications ? help Back to Top
  1. Eulgem T,Rushton PJ,Robatzek S,Somssich IE
    The WRKY superfamily of plant transcription factors.
    Trends Plant Sci., 2000. 5(5): p. 199-206
    [PMID:10785665]
  2. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  3. Kim KC,Lai Z,Fan B,Chen Z
    Arabidopsis WRKY38 and WRKY62 transcription factors interact with histone deacetylase 19 in basal defense.
    Plant Cell, 2008. 20(9): p. 2357-71
    [PMID:18776063]
  4. Ren X, et al.
    ABO3, a WRKY transcription factor, mediates plant responses to abscisic acid and drought tolerance in Arabidopsis.
    Plant J., 2010. 63(3): p. 417-29
    [PMID:20487379]
  5. Van Aken O,Zhang B,Law S,Narsai R,Whelan J
    AtWRKY40 and AtWRKY63 modulate the expression of stress-responsive nuclear genes encoding mitochondrial and chloroplast proteins.
    Plant Physiol., 2013. 162(1): p. 254-71
    [PMID:23509177]
  6. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  7. Min JH, et al.
    Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element.
    Front Plant Sci, 2017. 8: p. 2100
    [PMID:29321786]