PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT1G74930.1

Common Name

ERF018, F25A4.10, F9E10.22, ORA47

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 195aa MW: 21898.4 Da PI: 4.5027

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT1G74930.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	59.6	7.4e-19	19	69	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaarkkleg 55 s+ykGVr +k +g+Wv+eIr p + r++lg+++t+e+Aa+a +aa +l+g AT1G74930.1 19 SKYKGVRKRK-WGKWVSEIRLP-----HsrERIWLGSYDTPEKAARAFDAAQFCLRG 69 89***999.******7.....335***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF54171	4.71E-21	19	78	IPR016177	DNA-binding domain
CDD	cd00018	2.17E-29	19	79	No hit	No description
Pfam	PF00847	7.4E-12	19	69	IPR001471	AP2/ERF domain
SMART	SM00380	4.8E-32	20	83	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	9.0E-29	20	78	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	22.089	20	77	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-9	21	32	IPR001471	AP2/ERF domain
PRINTS	PR00367	1.2E-9	43	59	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0001944	Biological Process	vasculature development
GO:0002213	Biological Process	defense response to insect
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009611	Biological Process	response to wounding
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0051301	Biological Process	cell division
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000037	anatomy	shoot apex
PO:0000293	anatomy	guard cell
PO:0008019	anatomy	leaf lamina base
PO:0009005	anatomy	root
PO:0009009	anatomy	plant embryo
PO:0009025	anatomy	vascular leaf
PO:0009029	anatomy	stamen
PO:0009030	anatomy	carpel
PO:0009031	anatomy	sepal
PO:0009032	anatomy	petal
PO:0009046	anatomy	flower
PO:0009047	anatomy	stem
PO:0009052	anatomy	flower pedicel
PO:0020030	anatomy	cotyledon
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0020137	anatomy	leaf apex
PO:0025022	anatomy	collective leaf structure
PO:0025281	anatomy	pollen
PO:0001185	developmental stage	plant embryo globular stage
PO:0004507	developmental stage	plant embryo bilateral stage
PO:0007064	developmental stage	LP.12 twelve leaves visible stage
PO:0007095	developmental stage	LP.08 eight leaves visible stage
PO:0007098	developmental stage	LP.02 two leaves visible stage
PO:0007103	developmental stage	LP.10 ten leaves visible stage
PO:0007115	developmental stage	LP.04 four leaves visible stage
PO:0007123	developmental stage	LP.06 six leaves visible stage
PO:0007611	developmental stage	petal differentiation and expansion stage
PO:0007616	developmental stage	flowering stage

Sequence ? help Back to Top
Protein Sequence Length: 195 aa Download sequence Send to blast
MVKQAMKEEE KKRNTAMQSK YKGVRKRKWG KWVSEIRLPH SRERIWLGSY DTPEKAARAF 60 DAAQFCLRGG DANFNFPNNP PSISVEKSLT PPEIQEAAAR FANTFQDIVK GEEESGLVPG 120 SEIRPESPST SASVATSTVD YDFSFLDLLP MNFGFDSFSD DFSGFSGGDR FTEILPIEDY 180 GGESLLDESL ILWDF

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	2e-15	16	78	10	73	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	10	27	KKRNTAMQSKYKGVRKRK
2	21	27	KGVRKRK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.34825	0.0	bud\| leaf\| seed

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	30699058	0.0
Genevisible	262211_at	0.0
Expression Atlas	AT1G74930	-
AtGenExpress	AT1G74930	-
ATTED-II	AT1G74930	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10.
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
ORA47 is proposed to play a role in the biosynthesis of jasmonic acid and abscissic acid and in regulating the biosynthesis and/or signaling of a suite of phytohormone genes when plants are subjected to wounding and water stress. [PMID: 26974851]

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00601	PBM	24477691	Download

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT1G74930.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source	Target Gene (A: Activate/R: Repress)
ATRM	AT1G17420(A)

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT1G74930

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC013258	0.0	AC013258.5 Arabidopsis thaliana chromosome 1 BAC F9E10 genomic sequence, complete sequence.
GenBank	AY128309	0.0	AY128309.1 Arabidopsis thaliana AP2 domain containing protein, putative (At1g74930) mRNA, complete cds.
GenBank	BT003348	0.0	BT003348.1 Arabidopsis thaliana AP2 domain containing protein, putative (At1g74930) mRNA, complete cds.
GenBank	CP002684	0.0	CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
GenBank	F25A4	0.0	AC008263.2 Arabidopsis thaliana chromosome 1 BAC F25A4 sequence, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_177631.1	1e-142	Integrase-type DNA-binding superfamily protein
Swissprot	Q9S7L5	1e-143	ERF18_ARATH; Ethylene-responsive transcription factor ERF018
TrEMBL	A0A178W260	1e-141	A0A178W260_ARATH; ORA47
STRING	AT1G74930.1	1e-142	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM1614	28	90
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT1G74930.1
Entrez Gene	843832
iHOP	AT1G74930
wikigenes	AT1G74930

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Ma S,Gong Q,Bohnert HJ Dissecting salt stress pathways. J. Exp. Bot., 2006. 57(5): p. 1097-107 [PMID:16510518] Walley JW, et al. Mechanical stress induces biotic and abiotic stress responses via a novel cis-element. PLoS Genet., 2007. 3(10): p. 1800-12 [PMID:17953483] Pauwels L, et al. Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells. Proc. Natl. Acad. Sci. U.S.A., 2008. 105(4): p. 1380-5 [PMID:18216250] Cartagena JA, et al. The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen. Dev. Biol., 2008. 315(2): p. 355-68 [PMID:18252252] Ferreira FJ,Guo C,Coleman JR Reduction of plastid-localized carbonic anhydrase activity results in reduced Arabidopsis seedling survivorship. Plant Physiol., 2008. 147(2): p. 585-94 [PMID:18434607] Ascencio-Ib Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. Plant Physiol., 2008. 148(1): p. 436-54 [PMID:18650403] Pauwels L,Goossens A Fine-tuning of early events in the jasmonate response. Plant Signal Behav, 2008. 3(10): p. 846-7 [PMID:20140232] Kerchev PI, et al. The transcription factor ABI4 Is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis. Plant Cell, 2011. 23(9): p. 3319-34 [PMID:21926335] Etchells JP,Provost CM,Turner SR Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling. PLoS Genet., 2012. 8(11): p. e1002997 [PMID:23166504] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Lumba S, et al. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Dev. Cell, 2014. 29(3): p. 360-72 [PMID:24823379] Jin J, et al. An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors. Mol. Biol. Evol., 2015. 32(7): p. 1767-73 [PMID:25750178] Chen HY, et al. ORA47 (octadecanoid-responsive AP2/ERF-domain transcription factor 47) regulates jasmonic acid and abscisic acid biosynthesis and signaling through binding to a novel cis-element. New Phytol., 2016. 211(2): p. 599-613 [PMID:26974851] Hickman R, et al. Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network. Plant Cell, 2017. 29(9): p. 2086-2105 [PMID:28827376]