PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G40350.1

Common Name

DREB2H, ERF047, T3G21.12

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 157aa MW: 17791.6 Da PI: 10.6001

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G40350.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	51	3.5e-16	65	115	1	55
AP2 1 sgykGVrwdkkrgrWvAeIrdpsengkr.krfslgkfgtaeeAakaaiaarkkleg 55 ++y+GVr++ +g+WvAeIr+p g r ++ +lg+f + +eAa a+++a k+++g AT2G40350.1 65 CDYTGVRQRT-WGKWVAEIREP---G-RgAKLWLGTFSSSYEAALAYDEASKAIYG 115 68***999.******8...4.45*******************999887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Pfam	PF00847	6.5E-12	65	115	IPR001471	AP2/ERF domain
CDD	cd00018	3.56E-26	65	123	No hit	No description
PROSITE profile	PS51032	19.388	66	123	IPR001471	AP2/ERF domain
SMART	SM00380	1.5E-29	66	129	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	2.88E-18	67	124	IPR016177	DNA-binding domain
PRINTS	PR00367	6.9E-8	67	78	IPR001471	AP2/ERF domain
Gene3D	G3DSA:3.30.730.10	1.4E-26	67	123	IPR001471	AP2/ERF domain
PRINTS	PR00367	6.9E-8	89	105	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0010286	Biological Process	heat acclimation
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 157 aa Download sequence Send to blast
MPRKRKSRGT RDVAEILRKW REYNEQTEAD SCIDGGGSKP IRKAPPKRSR KGCMKGKGGP 60 ENGICDYTGV RQRTWGKWVA EIREPGRGAK LWLGTFSSSY EAALAYDEAS KAIYGQSARL 120 NLPLLPLCQA RLLHFLMNLK FVHVRIQMQD LVLVRSD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1gcc_A	8e-16	67	124	3	61	ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
2gcc_A	9e-16	67	124	6	64	ATERF1
3gcc_A	9e-16	67	124	6	64	ATERF1
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Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.50673	0.0	flower

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	79572106	0.0
Genevisible	263823_s_at	0.0
Expression Atlas	AT2G40350	-
AtGenExpress	AT2G40350	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the DREB subfamily A-2 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are eight members in this subfamily including DREB2A AND DREB2B that are involved in response to drought.
UniProt	Putative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. {ECO:0000250, ECO:0000269\|PubMed:11798174}.

Function -- GeneRIF ? help Back to Top
A trans activator involved in cold acclimatization. [PMID: 15341633]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G40350.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G40350

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AC007020	0.0	AC007020.5 Arabidopsis thaliana chromosome 2 clone T3G21 map g4514, complete sequence.
GenBank	CP002685	0.0	CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_181566.2	1e-114	Integrase-type DNA-binding superfamily protein
Swissprot	Q9SIZ0	1e-115	DRE2H_ARATH; Putative dehydration-responsive element-binding protein 2H
TrEMBL	A0A1P8B1T1	1e-111	A0A1P8B1T1_ARATH; Integrase-type DNA-binding superfamily protein
STRING	AT2G40350.1	1e-113	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM8532	25	38
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT2G40350.1
Entrez Gene	818628
iHOP	AT2G40350
wikigenes	AT2G40350

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Sakuma Y, et al. DNA-binding specificity of the ERF/AP2 domain of Arabidopsis DREBs, transcription factors involved in dehydration- and cold-inducible gene expression. Biochem. Biophys. Res. Commun., 2002. 290(3): p. 998-1009 [PMID:11798174] Rizhsky L, et al. When defense pathways collide. The response of Arabidopsis to a combination of drought and heat stress. Plant Physiol., 2004. 134(4): p. 1683-96 [PMID:15047901] Zhang X, et al. Freezing-sensitive tomato has a functional CBF cold response pathway, but a CBF regulon that differs from that of freezing-tolerant Arabidopsis. Plant J., 2004. 39(6): p. 905-19 [PMID:15341633] Vanderauwera S, et al. Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis. Plant Physiol., 2005. 139(2): p. 806-21 [PMID:16183842] Lee BH,Henderson DA,Zhu JK The Arabidopsis cold-responsive transcriptome and its regulation by ICE1. Plant Cell, 2005. 17(11): p. 3155-75 [PMID:16214899] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Lim CJ, et al. Gene expression profiles during heat acclimation in Arabidopsis thaliana suspension-culture cells. J. Plant Res., 2006. 119(4): p. 373-83 [PMID:16807682] Zhang X,Wollenweber B,Jiang D,Liu F,Zhao J Water deficits and heat shock effects on photosynthesis of a transgenic Arabidopsis thaliana constitutively expressing ABP9, a bZIP transcription factor. J. Exp. Bot., 2008. 59(4): p. 839-48 [PMID:18272919] Welling A,Palva ET Involvement of CBF transcription factors in winter hardiness in birch. Plant Physiol., 2008. 147(3): p. 1199-211 [PMID:18467468] Yang TJ,Perry PJ,Ciani S,Pandian S,Schmidt W Manganese deficiency alters the patterning and development of root hairs in Arabidopsis. J. Exp. Bot., 2008. 59(12): p. 3453-64 [PMID:18772308] Huang Y,Li CY,Biddle KD,Gibson SI Identification, cloning and characterization of sis7 and sis10 sugar-insensitive mutants of Arabidopsis. BMC Plant Biol., 2008. 8: p. 104 [PMID:18854047] Efroni I, et al. Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses. Dev. Cell, 2013. 24(4): p. 438-45 [PMID:23449474]