PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT2G41130.1

Common Name

BHLH106, EN56, T3K9.10

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

bHLH

Protein Properties

Length: 253aa MW: 27977.8 Da PI: 7.9164

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT2G41130.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.6	3e-10	69	115	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 r+h+e+ErrRR+riNs +++Lr +l + K +Ka+ L k+v+ +++L AT2G41130.1 69 RNHKEAERRRRERINSHLNKLRNVLSCN-----SKTDKATLLAKVVQRVREL 115 58*********************997.....7**********998887 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	14.449	66	115	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	2.22E-12	69	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.1E-8	69	115	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	6.9E-12	69	126	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	3.2E-9	72	121	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0042538	Biological Process	hyperosmotic salinity response
GO:0005634	Cellular Component	nucleus
GO:0009941	Cellular Component	chloroplast envelope
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0046983	Molecular Function	protein dimerization activity

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000293	anatomy	guard cell

Sequence ? help Back to Top
Protein Sequence Length: 253 aa Download sequence Send to blast
MQPETSDQML YSFLAGNEVG GGGYCVSGDY MTTMQSLCGS SSSTSSYYPL AISGIGETMA 60 QDRALAALRN HKEAERRRRE RINSHLNKLR NVLSCNSKTD KATLLAKVVQ RVRELKQQTL 120 ETSDSDQTLL PSETDEISVL HFGDYSNDGH IIFKASLCCE DRSDLLPDLM EILKSLNMKT 180 LRAEMVTIGG RTRSVLVVAA DKEMHGVESV HFLQNALKSL LERSSKSLME RSSGGGGGER 240 SKRRRALDHI IMV

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	74	79	ERRRRE

Expression -- Microarray ? help Back to Top
Source	ID	E-value
GEO	30688536	0.0
Expression Atlas	AT2G41130	-
AtGenExpress	AT2G41130	-

Function -- GeneRIF ? help Back to Top
locates at a branching point in abiotic stress response network by interacting directly to the G-box in genes conferring salt tolerance [PMID: 25978450]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT2G41130.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT5G11260

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT2G41130

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AK119059	0.0	AK119059.1 Arabidopsis thaliana At2g41130 mRNA for putative bHLH transcription factor (bHLH106), complete cds, clone: RAFL21-40-D23.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_181646.1	0.0	basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Swissprot	O80674	0.0	BH106_ARATH; Transcription factor bHLH106
TrEMBL	A0A178VRM6	0.0	A0A178VRM6_ARATH; Uncharacterized protein
STRING	AT2G41130.1	0.0	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM3642	27	62
Representative plant	OGRP377	15	106

Link Out ? help Back to Top
Phytozome	AT2G41130.1
Entrez Gene	818712
iHOP	AT2G41130
wikigenes	AT2G41130

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Seki M, et al. Functional annotation of a full-length Arabidopsis cDNA collection. Science, 2002. 296(5565): p. 141-5 [PMID:11910074] Heim MA, et al. The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. Mol. Biol. Evol., 2003. 20(5): p. 735-47 [PMID:12679534] Toledo-Ortiz G,Huq E,Quail PH The Arabidopsis basic/helix-loop-helix transcription factor family. Plant Cell, 2003. 15(8): p. 1749-70 [PMID:12897250] Froehlich JE, et al. Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis. J. Proteome Res., 2003 Jul-Aug. 2(4): p. 413-25 [PMID:12938931] Yamada K, et al. Empirical analysis of transcriptional activity in the Arabidopsis genome. Science, 2003. 302(5646): p. 842-6 [PMID:14593172] Bailey PC, et al. Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. Plant Cell, 2003. 15(11): p. 2497-502 [PMID:14600211] Gong W, et al. The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors. Mol Plant, 2008. 1(1): p. 27-41 [PMID:19802365] Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature. Differentiation, 2010. 80(1): p. 1-8 [PMID:20219281] Ahmad A, et al. bHLH106 Integrates Functions of Multiple Genes through Their G-Box to Confer Salt Tolerance on Arabidopsis. PLoS ONE, 2015. 10(5): p. e0126872 [PMID:25978450] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470]