PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

AT3G23230.1

Common Name

AtERF98, AtTDR1, ERF098, ERF98, K14B15.14, TDR1

Organism

Arabidopsis thaliana

Taxonomic ID

3702

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis

Family

ERF

Protein Properties

Length: 139aa MW: 16096.5 Da PI: 7.5189

Description

ERF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
AT3G23230.1	genome	TAIR	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	AP2	65.2	1.3e-20	19	70	2	56
AP2 2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 +++GVr+++ +g+++AeIrdps ng +r +lg+f taeeAa+a+++a+ +l+g+ AT3G23230.1 19 RFRGVRRRP-WGKFAAEIRDPSRNG--ARLWLGTFETAEEAARAYDRAAFNLRGH 70 69*****.******98887..************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00018	3.50E-28	18	78	No hit	No description
Gene3D	G3DSA:3.30.730.10	2.0E-31	19	79	IPR001471	AP2/ERF domain
SMART	SM00380	5.2E-37	19	83	IPR001471	AP2/ERF domain
Pfam	PF00847	6.3E-15	19	70	IPR001471	AP2/ERF domain
PROSITE profile	PS51032	24.684	19	77	IPR001471	AP2/ERF domain
SuperFamily	SSF54171	1.18E-23	19	78	IPR016177	DNA-binding domain
PRINTS	PR00367	3.5E-11	20	31	IPR001471	AP2/ERF domain
PRINTS	PR00367	3.5E-11	43	59	IPR001471	AP2/ERF domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009873	Biological Process	ethylene-activated signaling pathway
GO:0010200	Biological Process	response to chitin
GO:0005634	Cellular Component	nucleus
GO:0003677	Molecular Function	DNA binding
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Plant Ontology ? help Back to Top
PO Term	PO Category	PO Description
PO:0000037	anatomy	shoot apex
PO:0000293	anatomy	guard cell
PO:0009005	anatomy	root
PO:0009025	anatomy	vascular leaf
PO:0020038	anatomy	petiole
PO:0020100	anatomy	hypocotyl
PO:0007064	developmental stage	LP.12 twelve leaves visible stage

Sequence ? help Back to Top
Protein Sequence Length: 139 aa Download sequence Send to blast
MESSNRSSNN QSQDDKQARF RGVRRRPWGK FAAEIRDPSR NGARLWLGTF ETAEEAARAY 60 DRAAFNLRGH LAILNFPNEY YPRMDDYSLR PPYASSSSSS SSGSTSTNVS RQNQREVFEF 120 EYLDDKVLEE LLDSEERKR

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5wx9_A	2e-32	17	127	12	114	Ethylene-responsive transcription factor ERF096
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
At.37741	0.0	root

Expression -- Microarray ? help Back to Top
Source	ID	E-value
Genevisible	257918_at	1e-143
Expression Atlas	AT3G23230	-
AtGenExpress	AT3G23230	-
ATTED-II	AT3G23230	-

Functional Description ? help Back to Top
Source	Description
TAIR	encodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProt	Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.

Function -- GeneRIF ? help Back to Top
ERF98 is a transcriptional activator, and its C-terminal region (CMIX-1) is involved in transcriptional activation. [ERF98] [PMID: 22321262] The regulation of AtERF98 in Ascorbic acid biosynthesis contributes to enhanced salt tolerance in Arabidopsis. [ERF98] [PMID: 22417285]

Cis-element ? help Back to Top
Source	Link
PlantRegMap	AT3G23230.1

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Regulation -- Hormone ? help Back to Top
Source	Hormone
AHD	ethylene

Interaction ? help Back to Top
Source	Intact With
BioGRID	AT5G11260

Phenotype -- Mutation ? help Back to Top
Source	ID
T-DNA Express	AT3G23230

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	AB025608	0.0	AB025608.1 Arabidopsis thaliana genomic DNA, chromosome 3, TAC clone:K14B15.
GenBank	AJ580377	0.0	AJ580377.1 Arabidopsis thaliana mRNA for putative ethylene responsive element binding protein.
GenBank	CP002686	0.0	CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	NP_188964.2	2e-97	Integrase-type DNA-binding superfamily protein
Swissprot	Q9LTC5	2e-98	ERF98_ARATH; Ethylene-responsive transcription factor ERF098
TrEMBL	A0A178VBH2	6e-95	A0A178VBH2_ARATH; TDR1
STRING	AT3G23230.1	9e-97	(Arabidopsis thaliana)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Malvids	OGEM10	28	1650
Representative plant	OGRP6	16	1718

Link Out ? help Back to Top
Phytozome	AT3G23230.1
Entrez Gene	821901
iHOP	AT3G23230
wikigenes	AT3G23230

Publications ? help Back to Top
Riechmann JL, et al. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science, 2000. 290(5499): p. 2105-10 [PMID:11118137] Dal Bosco C, et al. Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. J. Biol. Chem., 2004. 279(2): p. 1060-9 [PMID:14576160] Gong W, et al. Genome-wide ORFeome cloning and analysis of Arabidopsis transcription factor genes. Plant Physiol., 2004. 135(2): p. 773-82 [PMID:15208423] McGrath KC, et al. Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression. Plant Physiol., 2005. 139(2): p. 949-59 [PMID:16183832] Vanderauwera S, et al. Genome-wide analysis of hydrogen peroxide-regulated gene expression in Arabidopsis reveals a high light-induced transcriptional cluster involved in anthocyanin biosynthesis. Plant Physiol., 2005. 139(2): p. 806-21 [PMID:16183842] Suzuki N, et al. Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c. Plant Physiol., 2005. 139(3): p. 1313-22 [PMID:16244138] Nakano T,Suzuki K,Fujimura T,Shinshi H Genome-wide analysis of the ERF gene family in Arabidopsis and rice. Plant Physiol., 2006. 140(2): p. 411-32 [PMID:16407444] Ma S,Gong Q,Bohnert HJ Dissecting salt stress pathways. J. Exp. Bot., 2006. 57(5): p. 1097-107 [PMID:16510518] Dombrecht B, et al. MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis. Plant Cell, 2007. 19(7): p. 2225-45 [PMID:17616737] Zhao J, et al. Analysis of gene expression profiles in response to Sclerotinia sclerotiorum in Brassica napus. Planta, 2007. 227(1): p. 13-24 [PMID:17665211] Libault M,Wan J,Czechowski T,Udvardi M,Stacey G Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact., 2007. 20(8): p. 900-11 [PMID:17722694] Gong W, et al. The development of protein microarrays and their applications in DNA-protein and protein-protein interaction analyses of Arabidopsis transcription factors. Mol Plant, 2008. 1(1): p. 27-41 [PMID:19802365] Ou B, et al. A high-throughput screening system for Arabidopsis transcription factors and its application to Med25-dependent transcriptional regulation. Mol Plant, 2011. 4(3): p. 546-55 [PMID:21343311] Tiwari SB, et al. The EDLL motif: a potent plant transcriptional activation domain from AP2/ERF transcription factors. Plant J., 2012. 70(5): p. 855-65 [PMID:22321262] Zhang Z,Wang J,Zhang R,Huang R The ethylene response factor AtERF98 enhances tolerance to salt through the transcriptional activation of ascorbic acid synthesis in Arabidopsis. Plant J., 2012. 71(2): p. 273-87 [PMID:22417285] MEDIATOR25 acts as an integrative hub for the regulation of jasmonate-responsive gene expression in Arabidopsis. Plant Physiol., 2012. 160(1): p. 541-55 [PMID:22822211] Wang J,Zhang Z,Huang R Regulation of ascorbic acid synthesis in plants. Plant Signal Behav, 2013. 8(6): p. e24536 [PMID:23603957] Van den Broeck L, et al. From network to phenotype: the dynamic wiring of an Arabidopsis transcriptional network induced by osmotic stress. Mol. Syst. Biol., 2017. 13(12): p. 961 [PMID:29269383] Riechmann JL,Meyerowitz EM The AP2/EREBP family of plant transcription factors. Biol. Chem., 1998. 379(6): p. 633-46 [PMID:9687012]