PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT3G50330.1
Common NameBHLH37, EN117, F11C1.170, HEC2
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 231aa    MW: 25684.5 Da    PI: 10.0433
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT3G50330.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH26.31.3e-08134174954
                  HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                   r RR+ri +++  L++l+P       +K++ a++L +A++Y+k L
  AT3G50330.1 134 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIHYVKFL 174
                  699*****************87.....8****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.434125174IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.1E-14126184IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.31E-14129184IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003538.3E-14131180IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000106.4E-6135174IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000836.65E-6148179No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010500Biological Processtransmitting tissue development
GO:0048462Biological Processcarpel formation
GO:0080126Biological Processovary septum development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000030anatomyseptum
PO:0009056anatomyflower nectary
PO:0009073anatomystigma
PO:0020003anatomyplant ovule
PO:0020102anatomyportion of transmitting tissue
PO:0025281anatomypollen
PO:0007606developmental stagegynoecium development stage
PO:0007615developmental stageflower development stage
Sequence ? help Back to Top
Protein Sequence    Length: 231 aa     Download sequence    Send to blast
MDNSDILMNM MMQQMEKLPE HFSNSNPNPN PHNIMMLSES NTHPFFFNPT HSHLPFDQTM  60
PHHQPGLNFR YAPSPSSSLP EKRGGCSDNA NMAAMREMIF RIAVMQPIHI DPESVKPPKR  120
KNVRISKDPQ SVAARHRRER ISERIRILQR LVPGGTKMDT ASMLDEAIHY VKFLKKQVQS  180
LEEHAVVNGG GMTAVAGGAL AGTVGGGYGG KGCGIMRSDH HQMLGNAQIL R
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT3G50330
AtGenExpressAT3G50330
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the developing septum, transmitting tract and stigma. {ECO:0000269|PubMed:17855426}.
UniprotTISSUE SPECIFICITY: Gynoecium. {ECO:0000269|PubMed:17855426}.
Functional Description ? help Back to Top
Source Description
UniProtRequired for the female reproductive tract development and fertility. {ECO:0000269|PubMed:17855426}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT3G50330.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269|PubMed:17855426}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT3G50330
IntActSearch Q9SND4
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Impaired pollen tube growth. {ECO:0000269|PubMed:17855426}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT3G50330
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAK1756790.0AK175679.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-18-N14.
GenBankAK1759120.0AK175912.1 Arabidopsis thaliana mRNA for putative bHLH transcription factor (bHLH037), complete cds, clone: RAFL22-57-C09.
GenBankAL1329760.0AL132976.2 Arabidopsis thaliana DNA chromosome 3, BAC clone F11C1.
GenBankBT0106070.0BT010607.1 Arabidopsis thaliana At3g50330 gene, complete cds.
GenBankCP0026860.0CP002686.1 Arabidopsis thaliana chromosome 3, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_190602.11e-172basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9SND41e-173HEC2_ARATH; Transcription factor HEC2
TrEMBLA0A178VGG71e-171A0A178VGG7_ARATH; HEC2
STRINGAT3G50330.11e-172(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM15592791
Representative plantOGRP7611568
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. De Paepe A,Vuylsteke M,Van Hummelen P,Zabeau M,Van Der Straeten D
    Transcriptional profiling by cDNA-AFLP and microarray analysis reveals novel insights into the early response to ethylene in Arabidopsis.
    Plant J., 2004. 39(4): p. 537-59
    [PMID:15272873]
  6. Gremski K,Ditta G,Yanofsky MF
    The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana.
    Development, 2007. 134(20): p. 3593-601
    [PMID:17855426]
  7. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  8. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  9. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  10. Schuster C,Gaillochet C,Lohmann JU
    Arabidopsis HECATE genes function in phytohormone control during gynoecium development.
    Development, 2015. 142(19): p. 3343-50
    [PMID:26293302]
  11. Zhu L, et al.
    A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis.
    Plant Cell, 2016. 28(4): p. 855-74
    [PMID:27073231]