PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT5G09750.1
Common NameBHLH43, EN119, F17I14.60, HEC3
Organism
Arabidopsis thaliana
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 224aa    MW: 25400.4 Da    PI: 6.6375
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT5G09750.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH26.71e-08134174954
                  HHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   9 ErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                   r RR+ri +++  L++l+P       +K++ a++L +A++Y+k L
  AT5G09750.1 134 ARHRRERISERIRILQRLVPGG-----TKMDTASMLDEAIRYVKFL 174
                  699*****************87.....8****************98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5088815.091125174IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474594.97E-14130185IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.2E-12131180IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.107.9E-12131182IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000104.3E-6135174IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.51E-6148179No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0010500Biological Processtransmitting tissue development
GO:0048462Biological Processcarpel formation
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000030anatomyseptum
PO:0000034anatomyvascular system
PO:0009073anatomystigma
PO:0020006anatomyfunicle
PO:0020102anatomyportion of transmitting tissue
PO:0007606developmental stagegynoecium development stage
PO:0007615developmental stageflower development stage
Sequence ? help Back to Top
Protein Sequence    Length: 224 aa     Download sequence    Send to blast
MNNYNMNPSL FQNYTWNNII NSSNNNNKND DHHHQHNNDP IGMAMDQYTQ LHIFNPFSSS  60
HFPPLSSSLT TTTLLSGDQE DDEDEEEPLE ELGAMKEMMY KIAAMQSVDI DPATVKKPKR  120
RNVRISDDPQ SVAARHRRER ISERIRILQR LVPGGTKMDT ASMLDEAIRY VKFLKRQIRL  180
LNNNTGYTPP PPQDQASQAV TTSWVSPPPP PSFGRGGRGV GELI
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO184160800.0
Expression AtlasAT5G09750-
AtGenExpressAT5G09750-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the developing septum, transmitting tract and stigma. {ECO:0000269|PubMed:17855426}.
UniprotTISSUE SPECIFICITY: Gynoecium. {ECO:0000269|PubMed:17855426}.
Functional Description ? help Back to Top
Source Description
UniProtRequired for the female reproductive tract development and fertility. {ECO:0000269|PubMed:17855426}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT5G09750.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Negatively regulated by ARF3/ETT in the abaxial gynoecium. {ECO:0000269|PubMed:17855426}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT3G57510(A)
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LXD8
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Impaired pollen tube growth. {ECO:0000269|PubMed:17855426}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT5G09750
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0207520.0AB020752.1 Arabidopsis thaliana genomic DNA, chromosome 5, P1 clone: MTH16.
GenBankAL3539940.0AL353994.1 Arabidopsis thaliana DNA chromosome 5, BAC clone F17I14 (ESSA project).
GenBankCP0026880.0CP002688.1 Arabidopsis thaliana chromosome 5 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_196537.11e-167basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9LXD81e-168HEC3_ARATH; Transcription factor HEC3
TrEMBLA0A178UMF11e-165A0A178UMF1_ARATH; HEC3
STRINGAT5G09750.11e-167(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM44492754
Representative plantOGRP7611568
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  5. Liljegren SJ, et al.
    Control of fruit patterning in Arabidopsis by INDEHISCENT.
    Cell, 2004. 116(6): p. 843-53
    [PMID:15035986]
  6. Czechowski T,Bari RP,Stitt M,Scheible WR,Udvardi MK
    Real-time RT-PCR profiling of over 1400 Arabidopsis transcription factors: unprecedented sensitivity reveals novel root- and shoot-specific genes.
    Plant J., 2004. 38(2): p. 366-79
    [PMID:15078338]
  7. Gremski K,Ditta G,Yanofsky MF
    The HECATE genes regulate female reproductive tract development in Arabidopsis thaliana.
    Development, 2007. 134(20): p. 3593-601
    [PMID:17855426]
  8. Ogawa M,Kay P,Wilson S,Swain SM
    ARABIDOPSIS DEHISCENCE ZONE POLYGALACTURONASE1 (ADPG1), ADPG2, and QUARTET2 are Polygalacturonases required for cell separation during reproductive development in Arabidopsis.
    Plant Cell, 2009. 21(1): p. 216-33
    [PMID:19168715]
  9. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  10. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  11. Schuster C,Gaillochet C,Lohmann JU
    Arabidopsis HECATE genes function in phytohormone control during gynoecium development.
    Development, 2015. 142(19): p. 3343-50
    [PMID:26293302]
  12. Zhu L, et al.
    A Negative Feedback Loop between PHYTOCHROME INTERACTING FACTORs and HECATE Proteins Fine-Tunes Photomorphogenesis in Arabidopsis.
    Plant Cell, 2016. 28(4): p. 855-74
    [PMID:27073231]