PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan001843

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

NAC

Protein Properties

Length: 394aa MW: 44304.8 Da PI: 5.2589

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S55086194	PU_unref	Unigene	View CDS
PUT-183a-Artemisia_annua-66646	PU_unref	plantGDB	View CDS
PUT-183a-Artemisia_annua-66647	PU_unref	plantGDB	View CDS
PUT-183a-Artemisia_annua-66648	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	168.3	2.5e-52	28	155	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 l+pGfrFhPtdeelv++yL++k+ gk++++ ++++e+d+yk+ePw+L + +k++++ewyfFs+ d+ky +g+r nrat +gyWkatgkd++v + k+e Aan001843 28 LAPGFRFHPTDEELVMYYLRRKACGKPFRF-QAVSEIDVYKSEPWELAdfSPLKTRDQEWYFFSPVDRKYGNGSRLNRATGKGYWKATGKDRAVRH-KSE 125 579***********************99.88**********75347788999**********************************.999 PP NAM 99 lvglkktLvfykgrapkgektdWvmheyrl 128 ++g+kktLvf++grap+g++t+Wvmheyrl Aan001843 126 TIGMKKTLVFHSGRAPDGKRTNWVMHEYRL 155 **************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	4.18E-62	24	178	IPR003441	NAC domain
PROSITE profile	PS51005	57.856	28	178	IPR003441	NAC domain
Pfam	PF02365	3.5E-28	30	155	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 394 aa Download sequence Send to blast
MGGHELMGVT SPPPPPPATT APPPPTSLAP GFRFHPTDEE LVMYYLRRKA CGKPFRFQAV 60 SEIDVYKSEP WELADFSPLK TRDQEWYFFS PVDRKYGNGS RLNRATGKGY WKATGKDRAV 120 RHKSETIGMK KTLVFHSGRA PDGKRTNWVM HEYRLLDQEL LRVGVTQDSF VLCRIFQKSG 180 LGPPNGDRYA PFLEEEWTDD TALMVPGGEA EDDMANGDET RAEGNDIAQE TSAKKILDRS 240 EDPQPITIVC KRERSEEDHA LTHEPELETF SLFHNKRSKP NDPNCSNANG SEDSTTTSQD 300 PRRALLEFPL LESIEAKECH PQTTLPSFDA ATLEKSVPPG YLKFISNLEN EILNVSMEKE 360 TLKIEVMRAQ AMIDILQSRI EVLSKENGGF RTGG

Sequence ? help Back to Top

Protein Sequence Length: 394 aa Download sequence Send to blast

MGGHELMGVT SPPPPPPATT APPPPTSLAP GFRFHPTDEE LVMYYLRRKA CGKPFRFQAV  60
SEIDVYKSEP WELADFSPLK TRDQEWYFFS PVDRKYGNGS RLNRATGKGY WKATGKDRAV  120
RHKSETIGMK KTLVFHSGRA PDGKRTNWVM HEYRLLDQEL LRVGVTQDSF VLCRIFQKSG  180
LGPPNGDRYA PFLEEEWTDD TALMVPGGEA EDDMANGDET RAEGNDIAQE TSAKKILDRS  240
EDPQPITIVC KRERSEEDHA LTHEPELETF SLFHNKRSKP NDPNCSNANG SEDSTTTSQD  300
PRRALLEFPL LESIEAKECH PQTTLPSFDA ATLEKSVPPG YLKFISNLEN EILNVSMEKE  360
TLKIEVMRAQ AMIDILQSRI EVLSKENGGF RTGG

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	9e-53	20	178	9	165	NO APICAL MERISTEM PROTEIN
1ut4_B	9e-53	20	178	9	165	NO APICAL MERISTEM PROTEIN
1ut7_A	9e-53	20	178	9	165	NO APICAL MERISTEM PROTEIN
1ut7_B	9e-53	20	178	9	165	NO APICAL MERISTEM PROTEIN
3swm_A	1e-52	20	178	12	168	NAC domain-containing protein 19
3swm_B	1e-52	20	178	12	168	NAC domain-containing protein 19
3swm_C	1e-52	20	178	12	168	NAC domain-containing protein 19
3swm_D	1e-52	20	178	12	168	NAC domain-containing protein 19
3swp_A	1e-52	20	178	12	168	NAC domain-containing protein 19
3swp_B	1e-52	20	178	12	168	NAC domain-containing protein 19
3swp_C	1e-52	20	178	12	168	NAC domain-containing protein 19
3swp_D	1e-52	20	178	12	168	NAC domain-containing protein 19
4dul_A	9e-53	20	178	9	165	NAC domain-containing protein 19
4dul_B	9e-53	20	178	9	165	NAC domain-containing protein 19
Search in ModeBase

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Aan.1983	0.0	leaf\| trichome

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Mostly expressed in floral organs, and, at low levels, in other organs. {ECO:0000269\|PubMed:25578968}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024991676.1	0.0	NAC domain containing protein 52-like
Swissprot	Q9SQX9	1e-109	NAC50_ARATH; NAC domain containing protein 50
TrEMBL	A0A2U1M7X2	0.0	A0A2U1M7X2_ARTAN; NAC domain-containing protein
STRING	XP_009619467.1	0.0	(Nicotiana tomentosiformis)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10480.2	1e-103	NAC domain containing protein 50

Publications ? help Back to Top
Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990]