PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan003719

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

bHLH

Protein Properties

Length: 241aa MW: 27052.5 Da PI: 8.0002

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S56468509	PU_unref	Unigene	View CDS
PUT-183a-Artemisia_annua-76783	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	41.1	3.1e-13	81	129	4	55
HHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS HLH 4 ahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55 ++ rE++RRd++N++f+eL e+l + +s K +K iL A++ I +L+ Aan003719 81 TKACREKKRRDKLNERFQELNEILDPG---RSAKTDKTVILADAIRMITHLR 129 6789********************9...9*****************95 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
CDD	cd00083	5.09E-12	67	131	No hit	No description
PROSITE profile	PS50888	13.363	77	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	5.2E-13	81	144	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.4E-11	81	128	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	1.57E-13	81	153	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.3E-9	83	134	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:1.20.5.1000	5.5E-4	145	176	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 241 aa Download sequence Send to blast
MEENNNINNN NNFFDFSLID HFPVPGGELP SLEPGFHWSA NSFPGSTSVV SKGFSDSYRQ 60 SDATKEDESR KRAHPGSCSS TKACREKKRR DKLNERFQEL NEILDPGRSA KTDKTVILAD 120 AIRMITHLRN EATNLKDSSQ DLLVKINELK VEKNELRDEK QKLKTDKERL EQQLKSTFCG 180 PPTAFYPPAH PVMPVPCPGP TPVGGNKFMP YMGFQGVPMW QFAPPAAVDT SKDHVHRSPL 240 A

Nucleic Localization Signal ? help Back to Top

No.	Start	End	Sequence
1	69	89	RKRAHPGSCSSTKACREKKRR
2	86	91	KKRRDK

Expression -- UniGene ? help Back to Top
UniGene ID	E-value	Expressed in
Aan.2173	0.0	leaf\| trichome

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023758717.1	1e-128	transcription factor bHLH115-like
Swissprot	Q9FH37	5e-66	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A2U1NS41	1e-166	A0A2U1NS41_ARTAN; Myc-type, basic helix-loop-helix (BHLH) domain-containing protein
STRING	XP_010267809.1	8e-79	(Nelumbo nucifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	1e-65	bHLH family protein

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]