PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan003774

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

bHLH

Protein Properties

Length: 235aa MW: 26383.1 Da PI: 5.4763

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S41948170	PU_ref	Unigene	View CDS
PUT-183a-Artemisia_annua-149362	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	38.2	2.6e-12	78	124	5	54
HHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 5 hnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 + rE++RRdr+N++f eL ++l + + +K +K +iL A++ I +L Aan003774 78 KAGREKQRRDRMNERFLELGSILEHG---RPPKTDKTAILSDAIRMIMQL 124 5669*******************8...89***************99 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
PROSITE profile	PS50888	12.913	73	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	8.2E-10	78	124	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamily	SSF47459	5.5E-13	79	143	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	1.1E-8	79	130	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:4.10.280.10	8.5E-13	81	147	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	8.13E-9	81	129	No hit	No description

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 235 aa Download sequence Send to blast
MEIDENSNWL LDYGLMDDIS TVVDYVAPPA VVVGFSWPSD IPAVSSEIES SFIDFEGLKG 60 AGSRKRLKSE CSNVCGSKAG REKQRRDRMN ERFLELGSIL EHGRPPKTDK TAILSDAIRM 120 IMQLRSEAER LNESNVDLQE KIKELKAEKN ELRDEKQRLK VEKEKLEQQV KTMNIGQPSY 180 LAHPTAMRGA FAAQEQAAGN KLMPFVGYPS VAMWQFMPSS VVDTSLDHVL RPPVA

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Widely expressed throughout development, mostly in vasculatures. {ECO:0000269\|PubMed:17028341}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Plays a role in resistance to amide-linked indole-3-acetic acid (IAA) conjugates such as IAA-Leu and IAA-Phe. May regulate gene expression in response to metal homeostasis changes. {ECO:0000269\|PubMed:17028341}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_023755205.1	1e-133	transcription factor ILR3-like
Swissprot	Q9FH37	1e-86	ILR3_ARATH; Transcription factor ILR3
TrEMBL	A0A2U1NLB8	1e-171	A0A2U1NLB8_ARTAN; Myc-type, basic helix-loop-helix (BHLH) domain-containing protein
STRING	VIT_12s0059g02650.t01	1e-109	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G54680.1	4e-71	bHLH family protein

Publications ? help Back to Top
Li X,Zhang H,Ai Q,Liang G,Yu D Two bHLH Transcription Factors, bHLH34 and bHLH104, Regulate Iron Homeostasis in Arabidopsis thaliana. Plant Physiol., 2016. 170(4): p. 2478-93 [PMID:26921305] Aparicio F,Pallás V The coat protein of Alfalfa mosaic virus interacts and interferes with the transcriptional activity of the bHLH transcription factor ILR3 promoting salicylic acid-dependent defence signalling response. Mol. Plant Pathol., 2017. 18(2): p. 173-186 [PMID:26929142] Liang G,Zhang H,Li X,Ai Q,Yu D bHLH transcription factor bHLH115 regulates iron homeostasis in Arabidopsis thaliana. J. Exp. Bot., 2017. 68(7): p. 1743-1755 [PMID:28369511] Ezer D, et al. The G-Box Transcriptional Regulatory Code in Arabidopsis. Plant Physiol., 2017. 175(2): p. 628-640 [PMID:28864470] Li B, et al. Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis. Plant Cell, 2018. 30(1): p. 178-195 [PMID:29317470] Min JH, et al. Arabidopsis Basic Helix-Loop-Helix 34 (bHLH34) Is Involved in Glucose Signaling through Binding to a GAGA Cis-Element. Front Plant Sci, 2017. 8: p. 2100 [PMID:29321786] Samira R, et al. The bHLH transcription factor ILR3 modulates multiple stress responses in Arabidopsis. Plant Mol. Biol., 2018. 97(4-5): p. 297-309 [PMID:29882068]