PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aan011302
Organism
Artemisia annua
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia
Family MYB
Protein Properties Length: 133aa    MW: 15269.2 Da    PI: 9.3811
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
gnl|UG|Aan#S55009818PU_refUnigeneView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding51.13.1e-161461148
                     TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding  1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                     rg+W+ eEd+ll + ++ +G g+W++ +++ g+ R++k+c++rw +yl
        Aan011302 14 RGAWSSEEDKLLTNHIQTYGEGQWRSLPSKAGLLRCGKSCRLRWMNYL 61
                     89******************************99************97 PP
2Myb_DNA-binding54.13.7e-1767112148
                      TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
  Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48 
                      rg++T+eE +++++++  +G++ W+ Ia ++  gRt++++k++w+++l
        Aan011302  67 RGSFTQEENDQIIHLHSIHGNK-WSFIATELK-GRTDNEIKNHWNSHL 112
                      89********************.********9.************986 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129412.807961IPR017930Myb domain
SuperFamilySSF466891.9E-2911108IPR009057Homeodomain-like
SMARTSM007177.2E-121363IPR001005SANT/Myb domain
PfamPF002492.4E-141461IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.601.2E-221568IPR009057Homeodomain-like
CDDcd001673.59E-91661No hitNo description
PROSITE profilePS5129427.15262116IPR017930Myb domain
SMARTSM007173.0E-1566114IPR001005SANT/Myb domain
PfamPF002491.6E-1567112IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.603.1E-2669115IPR009057Homeodomain-like
CDDcd001672.60E-1069112No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 133 aa     Download sequence    Send to blast
MGRTPCCSKV GLHRGAWSSE EDKLLTNHIQ TYGEGQWRSL PSKAGLLRCG KSCRLRWMNY  60
LRPGIKRGSF TQEENDQIIH LHSIHGNKWS FIATELKGRT DNEIKNHWNS HLKRKADNVG  120
DENQPAEDSK LQC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A8e-28121175109B-MYB
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: In seedlings, predominantly expressed in cotyledons. Restricted to the cotyledons and primary leaves. {ECO:0000269|PubMed:17419845}.
UniprotTISSUE SPECIFICITY: Expressed in seedlings, cotyledons and young leaves. {ECO:0000269|PubMed:17419845}.
Functional Description ? help Back to Top
Source Description
UniProtFlavonol-specific transcription activator involved in the regulation of several genes of flavonoid biosynthesis. Activates the expression of CHS, CHI, F3H and FLS1. Controls flavonol biosynthesis primarily in cotyledons and leaves (PubMed:17419845, PubMed:20731781). Confers tolerance to UV-B (PubMed:19895401). {ECO:0000269|PubMed:17419845, ECO:0000269|PubMed:19895401, ECO:0000269|PubMed:20731781}.
UniProtTranscriptional activator involved in cold stress response (PubMed:14675437, PubMed:20807373, PubMed:22246661). Regulates positively the expression of genes involved in reactive oxygen species (ROS) scavenging such as peroxidase and superoxide dismutase during cold stress. Transactivates a complex gene network that have major effects on stress tolerance and panicle development (PubMed:20807373). {ECO:0000269|PubMed:14675437, ECO:0000269|PubMed:20807373, ECO:0000269|PubMed:22246661}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: By cold stress. {ECO:0000269|PubMed:14675437, ECO:0000269|PubMed:20807373, ECO:0000269|Ref.2}.
UniProtINDUCTION: Triggered by HY5 in response to light and UV-B. {ECO:0000269|PubMed:19895401}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023745613.16e-73transcription factor MYB8-like
SwissprotQ7XBH44e-56MYB4_ORYSJ; Transcription factor MYB4
SwissprotQ9FJ076e-55MY111_ARATH; Transcription factor MYB111
TrEMBLA0A2U1L6U45e-84A0A2U1L6U4_ARTAN; Homeodomain-like protein
STRINGGLYMA19G44660.18e-60(Glycine max)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G49330.12e-57myb domain protein 111
Publications ? help Back to Top
  1. Park MR, et al.
    Supra-optimal expression of the cold-regulated OsMyb4 transcription factor in transgenic rice changes the complexity of transcriptional network with major effects on stress tolerance and panicle development.
    Plant Cell Environ., 2010. 33(12): p. 2209-30
    [PMID:20807373]
  2. Soltész A, et al.
    The rice Osmyb4 gene enhances tolerance to frost and improves germination under unfavourable conditions in transgenic barley plants.
    J. Appl. Genet., 2012. 53(2): p. 133-43
    [PMID:22246661]
  3. Pandey A,Misra P,Bhambhani S,Bhatia C,Trivedi PK
    Expression of Arabidopsis MYB transcription factor, AtMYB111, in tobacco requires light to modulate flavonol content.
    Sci Rep, 2014. 4: p. 5018
    [PMID:24846090]
  4. Lotkowska ME, et al.
    The Arabidopsis Transcription Factor MYB112 Promotes Anthocyanin Formation during Salinity and under High Light Stress.
    Plant Physiol., 2015. 169(3): p. 1862-80
    [PMID:26378103]
  5. Bulgakov VP,Veremeichik GN,Grigorchuk VP,Rybin VG,Shkryl YN
    The rolB gene activates secondary metabolism in Arabidopsis calli via selective activation of genes encoding MYB and bHLH transcription factors.
    Plant Physiol. Biochem., 2016. 102: p. 70-9
    [PMID:26913794]
  6. Zhou Z,Schenke D,Miao Y,Cai D
    Investigation of the crosstalk between the flg22 and the UV-B-induced flavonol pathway in Arabidopsis thaliana seedlings.
    Plant Cell Environ., 2017. 40(3): p. 453-458
    [PMID:28032363]
  7. Mondal SK,Roy S
    Genome-wide sequential, evolutionary, organizational and expression analyses of phenylpropanoid biosynthesis associated MYB domain transcription factors in Arabidopsis.
    J. Biomol. Struct. Dyn., 2018. 36(6): p. 1577-1601
    [PMID:28490275]
  8. Duan S, et al.
    Functional characterization of a heterologously expressed Brassica napus WRKY41-1 transcription factor in regulating anthocyanin biosynthesis in Arabidopsis thaliana.
    Plant Sci., 2018. 268: p. 47-53
    [PMID:29362083]