PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan015209

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

NAC

Protein Properties

Length: 203aa MW: 23133.9 Da PI: 9.7247

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
PUT-183a-Artemisia_annua-106763	PU_ref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	167.8	3.7e-52	37	164	1	128
NAM 1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkge 98 l+pGfrFhPtdeelv +yL++kv gk+l++ ++++e+d+yk+ePw+L ++++++++ewyfF++ dkky++g r nrat++gyWkatgkd+ v + kge Aan015209 37 LAPGFRFHPTDEELVRYYLRRKVCGKSLRF-QAVSEIDVYKSEPWELAdySSLNSRDQEWYFFCPVDKKYSNGARLNRATDRGYWKATGKDRYVRH-KGE 134 579***********************99.88**********85447888999**********************************.999 PP NAM 99 lvglkktLvfykgrapkgektdWvmheyrl 128 ++g kktLvf++grap g++tdWvmheyrl Aan015209 135 VIGSKKTLVFHSGRAPVGKRTDWVMHEYRL 164 **************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.22E-60	34	187	IPR003441	NAC domain
PROSITE profile	PS51005	57.766	37	187	IPR003441	NAC domain
Pfam	PF02365	2.3E-28	39	164	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 203 aa Download sequence Send to blast
MANVNGNGNG NVNGNELMVV VAPPQPPPPR QHNPTCLAPG FRFHPTDEEL VRYYLRRKVC 60 GKSLRFQAVS EIDVYKSEPW ELADYSSLNS RDQEWYFFCP VDKKYSNGAR LNRATDRGYW 120 KATGKDRYVR HKGEVIGSKK TLVFHSGRAP VGKRTDWVMH EYRLTDQELG KAGVAQDSYM 180 LCRIFQKSGL GPPNADRYAP FVX

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
3swm_A	1e-48	37	187	20	168	NAC domain-containing protein 19
3swm_B	1e-48	37	187	20	168	NAC domain-containing protein 19
3swm_C	1e-48	37	187	20	168	NAC domain-containing protein 19
3swm_D	1e-48	37	187	20	168	NAC domain-containing protein 19
3swp_A	1e-48	37	187	20	168	NAC domain-containing protein 19
3swp_B	1e-48	37	187	20	168	NAC domain-containing protein 19
3swp_C	1e-48	37	187	20	168	NAC domain-containing protein 19
3swp_D	1e-48	37	187	20	168	NAC domain-containing protein 19
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Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Mostly expressed in floral organs, and, at low levels, in other organs. {ECO:0000269\|PubMed:25578968}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional repressor that binds to the motif 5'-(C/T)A(C/A)G-3' in the promoter of target genes (PubMed:25578968). Binds also to the 5'-CTTGNNNNNCAAG-3' consensus sequence in chromatin (PubMed:26617990). Can bind to the mitochondrial dysfunction motif (MDM) present in the upstream regions of mitochondrial dysfunction stimulon (MDS) genes involved in mitochondrial retrograde regulation (MRR) (PubMed:24045019). Together with NAC051/NAC052 and JMJ14, regulates gene expression and flowering time by associating with the histone demethylase JMJ14, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968, PubMed:26617990). {ECO:0000269\|PubMed:24045019, ECO:0000269\|PubMed:25578968, ECO:0000269\|PubMed:26617990}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_009796718.1	1e-103	PREDICTED: NAC domain-containing protein 78-like
Refseq	XP_016464323.1	1e-103	PREDICTED: NAC domain-containing protein 78-like
Swissprot	Q9SQX9	3e-83	NAC50_ARATH; NAC domain containing protein 50
TrEMBL	A0A2U1NIJ0	1e-152	A0A2U1NIJ0_ARTAN; NAC domain-containing protein
STRING	XP_009796718.1	1e-103	(Nicotiana sylvestris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G10490.1	1e-84	NAC domain containing protein 52

Publications ? help Back to Top
Zhang S, et al. C-terminal domains of a histone demethylase interact with a pair of transcription factors and mediate specific chromatin association. Cell Discov, 2019. [PMID:26617990]