PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aan015750
Organism
Artemisia annua
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia
Family C2H2
Protein Properties Length: 171aa    MW: 19970.6 Da    PI: 9.7391
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
PUT-183a-Artemisia_annua-32411PU_refplantGDBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H219.82.1e-06628123
               EEETTTTEEESSHHHHHHHHHHT CS
    zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
               y+C++C+k F r  nL+ H r H
  Aan015750  6 YVCEICNKGFQRDQNLQLHRRGH 28
               9********************88 PP
2zf-C2H211.90.0007112130523
                TTTEEESSHHHHHHHHHHT CS
    zf-C2H2   5 dCgksFsrksnLkrHirtH 23 
                dCg+ Fsr++++ +H   +
  Aan015750 112 DCGTIFSRRDSFITHRAFC 130
                9**************8765 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576673.44E-7528No hitNo description
PfamPF121712.6E-5528IPR022755Zinc finger, double-stranded RNA binding
PROSITE profilePS5015711.136628IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.606.5E-6628IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SMARTSM003550.0098628IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280828IPR007087Zinc finger, C2H2
SMARTSM00355984777IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.602.9E-470103IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamilySSF576673.44E-777102No hitNo description
SMARTSM0035519082102IPR015880Zinc finger, C2H2-like
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 171 aa     Download sequence    Send to blast
MAKNKYVCEI CNKGFQRDQN LQLHRRGHNL PWKLRQRTST EIIKRVYICP EPTCVHHNPA  60
RALGDLTGIK KHFSRKHGEK KWKCEKCSKR YAVQCDWKAH SKICGTKEYK CDCGTIFSRR  120
DSFITHRAFC DALAEENNKL TQPMQQDHHH VPDQLNQNIN PTTSLTSHAL X
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5b3h_C5e-3478142367Zinc finger protein JACKDAW
5b3h_F5e-3478142367Zinc finger protein JACKDAW
Search in ModeBase
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Strongly up-regulated during seed development. {ECO:0000269|PubMed:21571950}.
UniprotTISSUE SPECIFICITY: At 3 days post anthesis (DPA), expressed in the chalazal endosperm region. By 6 DPA, expressed in the endosperm and embryo. In fully germinated seed, strongest expression in the root tip and not detected in the cotyledons. In 4-days old seedlings, restricted to the vasculature of the cotyledons, the shoot apical meristem region, and the root tip. By 8 days, restricted to newly emerged leaves. {ECO:0000269|PubMed:21571950}.
UniprotTISSUE SPECIFICITY: Observed in vegetative tissues. Mainly expressed in hypocotyls, petioles, shoot apices, root tips, and trichomes, and, at low levels, in leaves, stems and flowers. {ECO:0000269|PubMed:25035403}.
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor promoting the transition to germination by regulating light and hormonal signaling during seed maturation (PubMed:21571950). Acts as a positive regulator of phytochrome and/or gibberellin action (PubMed:21571950, PubMed:25035403). {ECO:0000269|PubMed:21571950, ECO:0000269|PubMed:25035403}.
UniProtTranscription factor that acts as a positive regulator of gibberellin (GA) action, homeostasis and signaling. GA converts the GAF1 complex from transcriptional activator to repressor via the degradation of DELLA proteins. {ECO:0000269|PubMed:25035403}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_023752077.11e-114protein indeterminate-domain 2-like isoform X1
RefseqXP_023752084.11e-114protein indeterminate-domain 7-like isoform X2
SwissprotQ9LVQ78e-89IDD1_ARATH; Zinc finger protein ENHYDROUS
SwissprotQ9SCQ63e-89IDD2_ARATH; Zinc finger protein GAI-ASSOCIATED FACTOR 1
TrEMBLA0A2U1MU991e-124A0A2U1MU99_ARTAN; Zinc finger, C2H2-like protein
TrEMBLA0A2U1MUA21e-124A0A2U1MUA2_ARTAN; Zinc finger, C2H2-like protein
STRINGXP_008369087.13e-96(Malus domestica)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G50700.11e-91indeterminate(ID)-domain 2
Publications ? help Back to Top
  1. Fukazawa J, et al.
    DELLAs function as coactivators of GAI-ASSOCIATED FACTOR1 in regulation of gibberellin homeostasis and signaling in Arabidopsis.
    Plant Cell, 2014. 26(7): p. 2920-38
    [PMID:25035403]
  2. Moreno-Risueno MA, et al.
    Transcriptional control of tissue formation throughout root development.
    Science, 2015. 350(6259): p. 426-30
    [PMID:26494755]
  3. Khare D, et al.
    Root avoidance of toxic metals requires the GeBP-LIKE 4 transcription factor in Arabidopsis thaliana.
    New Phytol., 2017. 213(3): p. 1257-1273
    [PMID:27768815]