PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aan018369

Organism

Artemisia annua

Taxonomic ID

35608

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; campanulids; Asterales; Asteraceae; Asteroideae; Anthemideae; Artemisiinae; Artemisia

Family

NAC

Protein Properties

Length: 333aa MW: 38277.2 Da PI: 4.7131

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Aan#S56550826	PU_ref	Unigene	View CDS
PUT-183a-Artemisia_annua-100406	PU_unref	plantGDB	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	166.1	1.2e-51	22	148	2	128
NAM 2 ppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLp..kkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgel 99 ppGfrFhPtdeelv +yLk+k+ +++l++ ++i evd+yk++P++Lp +k+k+++++w+fFs+rd++y++g r++rat +gyWkatgkd+++++ k++ Aan018369 22 PPGFRFHPTDEELVLYYLKRKICRRSLKM-DIIGEVDVYKWDPEELPgqSKLKSGDRQWFFFSPRDRRYPNGARSSRATMNGYWKATGKDRTIKR-KSSS 119 9**************************.99**********964489999***********************************9.8999 PP NAM 100 vglkktLvfykgrapkgektdWvmheyrl 128 vg kktLv+y+grap+g +tdWvmhey++ Aan018369 120 VGNKKTLVYYQGRAPSGLRTDWVMHEYTM 148 *************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101941	1.24E-58	20	171	IPR003441	NAC domain
PROSITE profile	PS51005	55.75	21	171	IPR003441	NAC domain
Pfam	PF02365	6.0E-27	22	147	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0003677	Molecular Function	DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 333 aa Download sequence Send to blast
MGSDMIDLVN VKKSKSGGKC FPPGFRFHPT DEELVLYYLK RKICRRSLKM DIIGEVDVYK 60 WDPEELPGQS KLKSGDRQWF FFSPRDRRYP NGARSSRATM NGYWKATGKD RTIKRKSSSV 120 GNKKTLVYYQ GRAPSGLRTD WVMHEYTMDE EELRRCPYAQ DHYVLYKVFK KSGPGPKNGE 180 QYGAPFVEEE WSDDDCLDVE ILLVQKLQPI PVNDFKSARE EEAPLSNDDI EFLHRIIEPE 240 VLPPLPQITE KAKMGLEPEP QPLVVEEDFL EMNDLLGPEP EKCSFDSLSE FDFCQEADAF 300 GSQPFELQPA YMDNLEFGPA NSGLVERSGE SRQ

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1ut4_A	2e-47	21	177	17	171	NO APICAL MERISTEM PROTEIN
1ut4_B	2e-47	21	177	17	171	NO APICAL MERISTEM PROTEIN
1ut7_A	2e-47	21	177	17	171	NO APICAL MERISTEM PROTEIN
1ut7_B	2e-47	21	177	17	171	NO APICAL MERISTEM PROTEIN
3swm_A	2e-47	21	177	20	174	NAC domain-containing protein 19
3swm_B	2e-47	21	177	20	174	NAC domain-containing protein 19
3swm_C	2e-47	21	177	20	174	NAC domain-containing protein 19
3swm_D	2e-47	21	177	20	174	NAC domain-containing protein 19
3swp_A	2e-47	21	177	20	174	NAC domain-containing protein 19
3swp_B	2e-47	21	177	20	174	NAC domain-containing protein 19
3swp_C	2e-47	21	177	20	174	NAC domain-containing protein 19
3swp_D	2e-47	21	177	20	174	NAC domain-containing protein 19
4dul_A	2e-47	21	177	17	171	NAC domain-containing protein 19
4dul_B	2e-47	21	177	17	171	NAC domain-containing protein 19
Search in ModeBase

Expression -- Description ? help Back to Top
Source	Description
Uniprot	TISSUE SPECIFICITY: Expressed in roots, rosette leaves, cauline leaves, shoot apex, stems and flowers. {ECO:0000269\|PubMed:17158162}.

Functional Description ? help Back to Top
Source	Description
UniProt	Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction. Binds directly to AOX1A promoter. Mediates mitochondrial retrograde signaling. {ECO:0000269\|PubMed:24045017}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By cold and drought stresses. {ECO:0000269\|PubMed:17158162}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_024977297.1	1e-172	NAC domain-containing protein 17-like isoform X1
Swissprot	Q9XIC5	1e-100	NAC17_ARATH; NAC domain-containing protein 17
TrEMBL	A0A2U1PVR6	0.0	A0A2U1PVR6_ARTAN; Uncharacterized protein
STRING	VIT_18s0001g01820.t01	1e-108	(Vitis vinifera)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G34190.1	1e-100	NAC domain containing protein 17

Publications ? help Back to Top
Duarte JM, et al. Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis. Mol. Biol. Evol., 2006. 23(2): p. 469-78 [PMID:16280546] Van Aken O, et al. Mitochondrial and Chloroplast Stress Responses Are Modulated in Distinct Touch and Chemical Inhibition Phases. Plant Physiol., 2016. 171(3): p. 2150-65 [PMID:27208304] Van Aken O,Ford E,Lister R,Huang S,Millar AH Retrograde signalling caused by heritable mitochondrial dysfunction is partially mediated by ANAC017 and improves plant performance. Plant J., 2016. 88(4): p. 542-558 [PMID:27425258] Hu Z, et al. Mitochondrial Defects Confer Tolerance against Cellulose Deficiency. Plant Cell, 2016. 28(9): p. 2276-2290 [PMID:27543091] Chi YH, et al. The membrane-tethered NAC transcription factor, AtNTL7, contributes to ER-stress resistance in Arabidopsis. Biochem. Biophys. Res. Commun., 2017. 488(4): p. 641-647 [PMID:28088515] Van Aken O,Pogson BJ Convergence of mitochondrial and chloroplastic ANAC017/PAP-dependent retrograde signalling pathways and suppression of programmed cell death. Cell Death Differ., 2017. 24(6): p. 955-960 [PMID:28498364] Cheng P, et al. The ERA-Related GTPase AtERG2 Associated with Mitochondria 18S RNA Is Essential for Early Embryo Development in Arabidopsis. Front Plant Sci, 2018. 9: p. 182 [PMID:29497438]