PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn004841

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

NAC

Protein Properties

Length: 559aa MW: 63103.9 Da PI: 6.2758

Description

NAC family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn004841	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	NAM	46.8	9.7e-15	319	360	7	49
NAM 7 FhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpk 49 FhPtdeelv++yL++kv++k+l++ + ik+vdiyk++PwdLp+ Achn004841 319 FHPTDEELVWFYLRRKVDNKPLTI-QLIKQVDIYKYDPWDLPT 360 ********************99.89************93 PP
2	NAM	39.2	2.2e-12	360	409	85	128
NAM 85 atgkdkevlsk......kgelvglkktLvfykgrapkgektdWvmheyrl 128 +tg dk+++s+ +++ +glkk+Lv+y+g+a kg+kt+W+mhe+rl Achn004841 360 TTGIDKPIYSStsgerdGRKCIGLKKSLVYYRGSAGKGTKTEWMMHEFRL 409 58999999997766655566**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.60.120.330	2.0E-60	20	282	IPR027443	Isopenicillin N synthase-like
SuperFamily	SSF51197	9.61E-58	21	282	No hit	No description
Pfam	PF14226	9.6E-17	58	164	IPR026992	Non-haem dioxygenase N-terminal domain
PROSITE profile	PS51471	10.201	202	321	IPR005123	Oxoglutarate/iron-dependent dioxygenase
Pfam	PF03171	1.7E-13	209	312	IPR005123	Oxoglutarate/iron-dependent dioxygenase
PROSITE profile	PS51005	14.087	267	442	IPR003441	NAC domain
Pfam	PF02365	1.2E-12	318	409	IPR003441	NAC domain
SuperFamily	SSF101941	4.18E-30	318	442	IPR003441	NAC domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0055114	Biological Process	oxidation-reduction process
GO:0003677	Molecular Function	DNA binding
GO:0016491	Molecular Function	oxidoreductase activity

Sequence ? help Back to Top
Protein Sequence Length: 559 aa Download sequence Send to blast
MVPCLDDGKS LFNFVVQEGN GVKGLVDSGL LNVPSQYVQP PNELIDKSNA YPHDQAPIDL 60 SGLDGPRHGQ VVEAIARAAE TFGFFQVVNH GVPLELLESL KDSAHCFFGQ APEKKAVYLK 120 GVSPSPLVKY GTSFVPEKEE ALEWKDYVSM VYTNDEDALK HWPNECKEVA LEYLKTSTKM 180 VKKIVQVLFE HLGLTVDEPR IDALIALKMV NMNFYPICPN PDLTVGVGRH SDMGILTVLL 240 QDGIGGLYVK LEHEESGNKG EWMEIPPVPG ALVINVGDTL QTVLVKLEER RRHYTSWKGA 300 RKVDGDTSSR YCFDHRCWFH PTDEELVWFY LRRKVDNKPL TIQLIKQVDI YKYDPWDLPT 360 TGIDKPIYSS TSGERDGRKC IGLKKSLVYY RGSAGKGTKT EWMMHEFRLP TDHLDDKTTK 420 HMDGKSIAQE AEVWTLCRIM KRNLSSKNFM PDWRELSAKR NNPIDASSKT SSVESGICHE 480 NYISFRVPEV RHNTERKQFV SHVGGERNQT INGQLSSICQ APSPVSSIFS PGMDELVKYG 540 DWDELRPVVE FAFDPFLM*

Sequence ? help Back to Top

Protein Sequence Length: 559 aa Download sequence Send to blast

MVPCLDDGKS LFNFVVQEGN GVKGLVDSGL LNVPSQYVQP PNELIDKSNA YPHDQAPIDL  60
SGLDGPRHGQ VVEAIARAAE TFGFFQVVNH GVPLELLESL KDSAHCFFGQ APEKKAVYLK  120
GVSPSPLVKY GTSFVPEKEE ALEWKDYVSM VYTNDEDALK HWPNECKEVA LEYLKTSTKM  180
VKKIVQVLFE HLGLTVDEPR IDALIALKMV NMNFYPICPN PDLTVGVGRH SDMGILTVLL  240
QDGIGGLYVK LEHEESGNKG EWMEIPPVPG ALVINVGDTL QTVLVKLEER RRHYTSWKGA  300
RKVDGDTSSR YCFDHRCWFH PTDEELVWFY LRRKVDNKPL TIQLIKQVDI YKYDPWDLPT  360
TGIDKPIYSS TSGERDGRKC IGLKKSLVYY RGSAGKGTKT EWMMHEFRLP TDHLDDKTTK  420
HMDGKSIAQE AEVWTLCRIM KRNLSSKNFM PDWRELSAKR NNPIDASSKT SSVESGICHE  480
NYISFRVPEV RHNTERKQFV SHVGGERNQT INGQLSSICQ APSPVSSIFS PGMDELVKYG  540
DWDELRPVVE FAFDPFLM*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4xae_A	6e-76	13	299	30	311	Feruloyl CoA ortho-hydroxylase 1
4xae_B	6e-76	13	299	30	311	Feruloyl CoA ortho-hydroxylase 1
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Involved in the pathway of sideretin biosynthesis from feruloyl CoA, a redox-active catecholic metabolite exuded by roots in response to iron deficiency in order to facilitate the uptake of iron; this pathway consists in the successive conversion from feruloyl CoA to scopoletin, from scopoletin to fraxetin and from fraxetin to sideretin. Catalyzes the biosynthesis of fraxetin via scopoletin hydroxylation. {ECO:0000269\|PubMed:29581584}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Strongly induced by iron deficiency, mainly in roots. {ECO:0000269\|PubMed:29581584}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_006422215.1	1e-150	feruloyl CoA ortho-hydroxylase 1
Refseq	XP_006475536.1	1e-150	feruloyl CoA ortho-hydroxylase 1-like
Swissprot	Q9LE86	1e-126	S8H_ARATH; Scopoletin 8-hydroxylase
TrEMBL	A0A2R6Q7J8	1e-180	A0A2R6Q7J8_ACTCH; Feruloyl CoA ortho-hydroxylase
STRING	XP_006475536.1	1e-150	(Citrus sinensis)
STRING	XP_006422215.1	1e-150	(Citrus clementina)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT2G43000.1	8e-46	NAC domain containing protein 42

Publications ? help Back to Top
Siwinska J, et al. Scopoletin 8-hydroxylase: a novel enzyme involved in coumarin biosynthesis and iron-deficiency responses in Arabidopsis. J. Exp. Bot., 2018. 69(7): p. 1735-1748 [PMID:29361149] Tsai HH, et al. Scopoletin 8-Hydroxylase-Mediated Fraxetin Production Is Crucial for Iron Mobilization. Plant Physiol., 2018. 177(1): p. 194-207 [PMID:29559590] Rajniak J, et al. Biosynthesis of redox-active metabolites in response to iron deficiency in plants. Nat. Chem. Biol., 2018. 14(5): p. 442-450 [PMID:29581584]