PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Achn041401

Organism

Actinidia chinensis

Taxonomic ID

3625

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia

Family

bHLH

Protein Properties

Length: 647aa MW: 71731.5 Da PI: 6.9839

Description

bHLH family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Achn041401	genome	IKGC	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	HLH	31.8	2.5e-10	138	186	3	54
HHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS HLH 3 rahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 ++h +E+ RR+riN+ +++Lr+ll ++ + Ka++L+++++ +k+L Achn041401 138 KNHAVAEQLRRQRINDHIDTLRQLLLPS---MTSRTVKASVLTETIRQVKEL 186 689**********************9...99***********999888 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF47459	4.45E-10	133	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profile	PS50888	13.376	135	186	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Pfam	PF00010	9.0E-8	138	186	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
CDD	cd00083	1.10E-8	138	191	No hit	No description
Gene3D	G3DSA:4.10.280.10	2.1E-9	139	193	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
SMART	SM00353	6.4E-8	141	192	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Gene3D	G3DSA:3.30.450.60	4.6E-36	320	439	No hit	No description
SuperFamily	SSF64356	5.95E-29	320	440	IPR011012	Longin-like domain
PROSITE profile	PS51072	16.668	437	646	IPR028565	Mu homology domain
Gene3D	G3DSA:2.60.40.1170	1.7E-30	458	589	No hit	No description
SuperFamily	SSF49447	3.79E-45	458	645	IPR028565	Mu homology domain
Pfam	PF00928	2.0E-26	458	564	IPR028565	Mu homology domain
Pfam	PF00928	5.2E-15	569	646	IPR028565	Mu homology domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006810	Biological Process	transport
GO:0005802	Cellular Component	trans-Golgi network
GO:0005829	Cellular Component	cytosol
GO:0030124	Cellular Component	AP-4 adaptor complex
GO:0046983	Molecular Function	protein dimerization activity

Sequence ? help Back to Top
Protein Sequence Length: 647 aa Download sequence Send to blast
MTCVRGTCHQ IELIKVQRQA MNSRHLSGNK SYADNGNGDE AAVSQPSKEV ILGDIIWVVD 60 DNAVSQSKKP SNRSAGEVLV RLYGSYKYMY VDPMACRTEF ENLQEENMLP KSMNKRSLMD 120 GGDCFSRFQK QKTEEAAKNH AVAEQLRRQR INDHIDTLRQ LLLPSMTSRT VKASVLTETI 180 RQVKELKKRV ADAALQFNGQ GWSGGGAATS GSFTFPDESD EATVSYCEGG EGRMVKVTVC 240 CEDRLSLNRE LTEAIHSVGA RAVRAEMGTV GGRTKAEVWV RLRQGGGEED VGSLTRALKA 300 LVDCRASGFS SLGRLIAVDR GDVQKGSAEI FFRKVKFWKE DGEEEAPPVF NVDGVNYFHV 360 KVVGLLFVAT TRSNVSPSLV LELLQRIARV IKDYLGVLNE DSFRKNFVLV YELLDEVVDF 420 GYVQTTSTEI LKSYVFNEPI VVDAARLPTL GPAGLFMGYI LTSEIDGTIQ MKSYLTGNPE 480 IRLALNEDLS IGIGGRSIYD YSGSSGSGAV ILDDCNFHES VQLDSFDMDR TLTLVPSDGE 540 FPVMNYRITQ EFKPPFRINA LIEEAGPLKI VGGSEHTLRA KLTFSQESHG NITKEAGPVS 600 MTFTIPMYNS SRLQVKYLQI AKKSKTYNPY RWVRYVTQAN SYVARI*

Sequence ? help Back to Top

Protein Sequence Length: 647 aa Download sequence Send to blast

MTCVRGTCHQ IELIKVQRQA MNSRHLSGNK SYADNGNGDE AAVSQPSKEV ILGDIIWVVD  60
DNAVSQSKKP SNRSAGEVLV RLYGSYKYMY VDPMACRTEF ENLQEENMLP KSMNKRSLMD  120
GGDCFSRFQK QKTEEAAKNH AVAEQLRRQR INDHIDTLRQ LLLPSMTSRT VKASVLTETI  180
RQVKELKKRV ADAALQFNGQ GWSGGGAATS GSFTFPDESD EATVSYCEGG EGRMVKVTVC  240
CEDRLSLNRE LTEAIHSVGA RAVRAEMGTV GGRTKAEVWV RLRQGGGEED VGSLTRALKA  300
LVDCRASGFS SLGRLIAVDR GDVQKGSAEI FFRKVKFWKE DGEEEAPPVF NVDGVNYFHV  360
KVVGLLFVAT TRSNVSPSLV LELLQRIARV IKDYLGVLNE DSFRKNFVLV YELLDEVVDF  420
GYVQTTSTEI LKSYVFNEPI VVDAARLPTL GPAGLFMGYI LTSEIDGTIQ MKSYLTGNPE  480
IRLALNEDLS IGIGGRSIYD YSGSSGSGAV ILDDCNFHES VQLDSFDMDR TLTLVPSDGE  540
FPVMNYRITQ EFKPPFRINA LIEEAGPLKI VGGSEHTLRA KLTFSQESHG NITKEAGPVS  600
MTFTIPMYNS SRLQVKYLQI AKKSKTYNPY RWVRYVTQAN SYVARI*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
2bp5_M	8e-47	348	645	46	434	CLATHRIN COAT ASSEMBLY PROTEIN AP50
2jkr_M	8e-47	348	645	46	434	AP-2 COMPLEX SUBUNIT MU-1
2jkr_U	8e-47	348	645	46	434	AP-2 COMPLEX SUBUNIT MU-1
2jkt_M	8e-47	348	645	46	434	AP-2 COMPLEX SUBUNIT MU-1
2jkt_U	8e-47	348	645	46	434	AP-2 COMPLEX SUBUNIT MU-1
2vgl_M	8e-47	348	645	46	434	AP-2 COMPLEX SUBUNIT MU-1
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Functional Description ? help Back to Top
Source	Description
UniProt	Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. {ECO:0000250}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	LN829629	6e-83	LN829629.1 Rhododendron simsii partial mRNA for clathrin adaptor complex subunit (RG3 gene).

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_015885953.1	0.0	AP-4 complex subunit mu isoform X1
Swissprot	Q9SB50	1e-169	AP4M_ARATH; AP-4 complex subunit mu
TrEMBL	A0A068UT51	0.0	A0A068UT51_COFCA; Uncharacterized protein
STRING	XP_006472485.1	0.0	(Citrus sinensis)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Asterids	OGEA8047	2	2

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G56770.1	1e-20	bHLH family protein

Publications ? help Back to Top
Boehm M,Bonifacino JS Adaptins: the final recount. Mol. Biol. Cell, 2001. 12(10): p. 2907-20 [PMID:11598180] Thum KE,Shasha DE,Lejay LV,Coruzzi GM Light- and carbon-signaling pathways. Modeling circuits of interactions. Plant Physiol., 2003. 132(2): p. 440-52 [PMID:12805577] Thum KE,Shin MJ,Palenchar PM,Kouranov A,Coruzzi GM Genome-wide investigation of light and carbon signaling interactions in Arabidopsis. Genome Biol., 2004. 5(2): p. R10 [PMID:14759260] Happel N, et al. Arabidopsis mu A-adaptin interacts with the tyrosine motif of the vacuolar sorting receptor VSR-PS1. Plant J., 2004. 37(5): p. 678-93 [PMID:14871308] Remans T, et al. A central role for the nitrate transporter NRT2.1 in the integrated morphological and physiological responses of the root system to nitrogen limitation in Arabidopsis. Plant Physiol., 2006. 140(3): p. 909-21 [PMID:16415211] Okamoto M, et al. High-affinity nitrate transport in roots of Arabidopsis depends on expression of the NAR2-like gene AtNRT3.1. Plant Physiol., 2006. 140(3): p. 1036-46 [PMID:16415212] Li W, et al. Dissection of the AtNRT2.1:AtNRT2.2 inducible high-affinity nitrate transporter gene cluster. Plant Physiol., 2007. 143(1): p. 425-33 [PMID:17085507] Wirth J, et al. Regulation of root nitrate uptake at the NRT2.1 protein level in Arabidopsis thaliana. J. Biol. Chem., 2007. 282(32): p. 23541-52 [PMID:17573350] Girin T, et al. Identification of a 150 bp cis-acting element of the AtNRT2.1 promoter involved in the regulation of gene expression by the N and C status of the plant. Plant Cell Environ., 2007. 30(11): p. 1366-80 [PMID:17897408] Wang R,Xing X,Crawford N Nitrite acts as a transcriptome signal at micromolar concentrations in Arabidopsis roots. Plant Physiol., 2007. 145(4): p. 1735-45 [PMID:17951451] Park M, et al. Arabidopsis μ-adaptin subunit AP1M of adaptor protein complex 1 mediates late secretory and vacuolar traffic and is required for growth. Proc. Natl. Acad. Sci. U.S.A., 2013. 110(25): p. 10318-23 [PMID:23733933] Fuji K, et al. The Adaptor Complex AP-4 Regulates Vacuolar Protein Sorting at the trans-Golgi Network by Interacting with VACUOLAR SORTING RECEPTOR1. Plant Physiol., 2016. 170(1): p. 211-9 [PMID:26546666]