PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aco000996.1
Organism
Ananas comosus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Bromeliaceae; Ananas
Family E2F/DP
Protein Properties Length: 405aa    MW: 44995.7 Da    PI: 9.235
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aco000996.1genomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP73.81.9e-232691171
      E2F_TDP  1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71
                 rk+ksL+ll+++f++l+++ + + v l+++a++L    v  +rRRiYDi+NVLe+++++++k+kn+++w+g
  Aco000996.1 26 RKQKSLGLLCSNFVSLYNRDDVESVGLDDAARRL---GV--ERRRIYDIVNVLESVGVLARKAKNRYSWIG 91
                 79*****************999************...**..****************************98 PP
2E2F_TDP82.24.2e-26164244171
      E2F_TDP   1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 
                  rkeksL+llt++f+kl+ ++++++++l+e+ak L+ +     ++++k+RR+YDi+NVL+++nliek     ++k+++rw g
  Aco000996.1 164 RKEKSLGLLTRNFVKLFLTTDADTISLDEAAKILLGDghetvNMRTKVRRLYDIANVLSSMNLIEKtqqleTRKPAFRWLG 244
                  79********************************************************************99*******87 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.7E-262292IPR011991Winged helix-turn-helix DNA-binding domain
SuperFamilySSF467852.54E-162590IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013727.8E-292691IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023191.4E-202791IPR003316E2F/DP family, winged-helix DNA-binding domain
Gene3DG3DSA:1.10.10.108.1E-24160245IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.6E-32164244IPR003316E2F/DP family, winged-helix DNA-binding domain
PfamPF023197.1E-21165244IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467854.35E-13166245IPR011991Winged helix-turn-helix DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0032876Biological Processnegative regulation of DNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 405 aa     Download sequence    Send to blast
MASPPPPLPP PPSFLESGCR HHAYSRKQKS LGLLCSNFVS LYNRDDVESV GLDDAARRLG  60
VERRRIYDIV NVLESVGVLA RKAKNRYSWI GFSGIPKALE DLKGNALRDI YGSYSDDYST  120
KVSDDEDDDK SADQMVNFES GKLSPTFNAS SSSTACCRAR SDQRKEKSLG LLTRNFVKLF  180
LTTDADTISL DEAAKILLGD GHETVNMRTK VRRLYDIANV LSSMNLIEKT QQLETRKPAF  240
RWLGTKGKPK EDNGVTIAIP PAPNTKQPNK RAFGTEITNV DLKRNRLNSA VDKKPNKMQM  300
RSDDLKQCNL TAQTQLQDSK GGFVFGPFQP TVAMKGGGDG QTSDDKVRDW ESLASSFRPQ  360
YHNQALSELF AHYMEAWKSW YSTMAQGSSA LQLPCSNSVF NQLL*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4yo2_A2e-37252363228Transcription factor E2F8
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269|PubMed:11786543, ECO:0000269|PubMed:11867638, ECO:0000269|PubMed:15649366, ECO:0000269|PubMed:18787127}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00397DAPTransfer from AT3G48160Download
Motif logo
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_020111111.10.0E2F transcription factor-like E2FE isoform X3
SwissprotQ8LSZ41e-109E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBLA0A199UE590.0A0A199UE59_ANACO; E2F transcription factor-like E2FE (Fragment)
STRINGXP_008798029.10.0(Phoenix dactylifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MonocotsOGMP31853884
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G48160.21e-110DP-E2F-like 1
Publications ? help Back to Top
  1. Chandran D, et al.
    Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid.
    Cell Host Microbe, 2014. 15(4): p. 506-13
    [PMID:24721578]
  2. Wang Z, et al.
    Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis.
    PLoS ONE, 2016. 11(8): p. e0160684
    [PMID:27505251]
  3. Heyman J,Polyn S,Eekhout T,De Veylder L
    Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.
    Plant Physiol., 2017. 175(1): p. 303-313
    [PMID:28698355]