PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aco014035.1

Organism

Ananas comosus

Taxonomic ID

4615

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; Liliopsida; Petrosaviidae; commelinids; Poales; Bromeliaceae; Ananas

Family

E2F/DP

Protein Properties

Length: 418aa MW: 45309.4 Da PI: 5.1327

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aco014035.1	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	84.5	8.5e-27	151	216	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++ll+++e+g+++ln +a+ L +v ++RRiYDi+NVLe+++liekk kn+irwkg Aco014035.1 151 RYDSSLGLLTKKFIRLLQQAEDGTLDLNRAADVL---EV--QKRRIYDITNVLEGVGLIEKKLKNRIRWKG 216 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	9.5E-29	148	217	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	4.08E-17	151	214	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.6E-34	151	216	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.2E-24	153	216	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	2.11E-42	227	334	No hit	No description
SuperFamily	SSF144074	2.51E-29	228	333	No hit	No description
Pfam	PF16421	3.2E-29	232	331	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 418 aa Download sequence Send to blast
MSSADGSPFP AAPPRRFPPP QLHRAPPQAA AAAGANARRF PLSAHLGPAS TSAAAAEPRC 60 FAAEDRKPPP GTSIRKQTNG TENIKVEHDE GAVEREGKEE FSTRILSTGS GVGSKRSRKT 120 KASRQKGAMQ ETPGTTEGVP GNSLLSASNC RYDSSLGLLT KKFIRLLQQA EDGTLDLNRA 180 ADVLEVQKRR IYDITNVLEG VGLIEKKLKN RIRWKGIDVS RPKEVDDQIA LLKAELESLY 240 AEDCKLDNMI RDIQEDLHAL AADENVQNWL FLTKEDITNI PAFQDSTLIA IKAPHGTSLE 300 VPDPNEGVGF PQRHYQILLR SSMGPIDCYL ISDHEEKHDV SNQNQHGAAR QSTENVSSGT 360 SEKGEEDDGE CKSSPDSFIS QDNTAGILRI APSDIDMGAD YWLSSDVGVS ATDTWGT*

Sequence ? help Back to Top

Protein Sequence Length: 418 aa Download sequence Send to blast

MSSADGSPFP AAPPRRFPPP QLHRAPPQAA AAAGANARRF PLSAHLGPAS TSAAAAEPRC  60
FAAEDRKPPP GTSIRKQTNG TENIKVEHDE GAVEREGKEE FSTRILSTGS GVGSKRSRKT  120
KASRQKGAMQ ETPGTTEGVP GNSLLSASNC RYDSSLGLLT KKFIRLLQQA EDGTLDLNRA  180
ADVLEVQKRR IYDITNVLEG VGLIEKKLKN RIRWKGIDVS RPKEVDDQIA LLKAELESLY  240
AEDCKLDNMI RDIQEDLHAL AADENVQNWL FLTKEDITNI PAFQDSTLIA IKAPHGTSLE  300
VPDPNEGVGF PQRHYQILLR SSMGPIDCYL ISDHEEKHDV SNQNQHGAAR QSTENVSSGT  360
SEKGEEDDGE CKSSPDSFIS QDNTAGILRI APSDIDMGAD YWLSSDVGVS ATDTWGT*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-24	151	217	7	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	-

Annotation -- Nucleotide ? help Back to Top
Source	Hit ID	E-value	Description
GenBank	KM664562	0.0	KM664562.1 Ananas bracteatus clone 49477 microsatellite sequence.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_020085582.1	0.0	transcription factor E2FB-like isoform X3
Swissprot	Q9FV71	1e-102	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A3Q0IEC3	1e-141	A0A3Q0IEC3_PHODC; transcription factor E2FB-like isoform X1
TrEMBL	A0A3Q0IJD2	1e-142	A0A3Q0IJD2_PHODC; transcription factor E2FB-like isoform X2
STRING	XP_008807578.1	1e-142	(Phoenix dactylifera)

Orthologous Group ? help Back to Top
Lineage	Orthologous Group ID	Taxa Number	Gene Number
Monocots	OGMP625	37	148

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.3	1e-104	E2F transcription factor 1

Link Out ? help Back to Top
Phytozome	Aco014035.1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]