PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ahy007365

Organism

Arachis hypogaea

Taxonomic ID

3818

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis

Family

E2F/DP

Protein Properties

Length: 439aa MW: 48774.4 Da PI: 4.9813

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Ahy#S58444232	PU_unref	Unigene	View CDS
gnl\|UG\|Ahy#S59540014	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	86.6	1.8e-27	120	185	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 r+++sL+llt+kf++l++++e+gi++ln++a++L +v ++RRiYDi+NVLe+++liekk kn+i+wkg Ahy007365 120 RYDSSLGLLTKKFINLIKQAEDGILDLNKAAETL---EV--QKRRIYDITNVLEGIGLIEKKLKNRIQWKG 185 6899****************************...99..**************************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	2.2E-29	116	187	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.2E-34	120	185	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	4.08E-17	120	183	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.2E-24	122	185	IPR003316	E2F/DP family, winged-helix DNA-binding domain
CDD	cd14660	3.90E-43	196	302	No hit	No description
SuperFamily	SSF144074	4.18E-31	199	301	No hit	No description
Pfam	PF16421	1.2E-30	201	300	IPR032198	E2F transcription factor, CC-MB domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 439 aa Download sequence Send to blast
MKRQVPLPST KPPFAPPADY HRFATDHRTT SQNDADAIAV KTPQLKRKSV TTDLEGDSGN 60 VTPASTEAVN SPFRTPISRK TGKASKSSRL TKCNRSGSQI PGSNISSPSA NNLAPSGPCR 120 YDSSLGLLTK KFINLIKQAE DGILDLNKAA ETLEVQKRRI YDITNVLEGI GLIEKKLKNR 180 IQWKGLDVSR PGQAVDSFAS LQAEVENLTN EEHRLDEQIR EMQERLRGVS EDENTQRYLF 240 VTEEDIKSLP SSQNETLIAI KAPYCTTLEV PDPDEVVDYP QRKYRIVLRS TTGPIDVYLL 300 SQFEEKFEIN GVNVGPNIPS RPDFNKHQST VVSNDRGKDL EMGIQDVYRP SDLSNSHDFA 360 GGITKIVPSD FESDADYWLL SDADVSITDM WRTEPGEVEW HNLETPKEDY CMTHVSPPPP 420 QTPPSNISEA PSASNPPVA

Sequence ? help Back to Top

Protein Sequence Length: 439 aa Download sequence Send to blast

MKRQVPLPST KPPFAPPADY HRFATDHRTT SQNDADAIAV KTPQLKRKSV TTDLEGDSGN  60
VTPASTEAVN SPFRTPISRK TGKASKSSRL TKCNRSGSQI PGSNISSPSA NNLAPSGPCR  120
YDSSLGLLTK KFINLIKQAE DGILDLNKAA ETLEVQKRRI YDITNVLEGI GLIEKKLKNR  180
IQWKGLDVSR PGQAVDSFAS LQAEVENLTN EEHRLDEQIR EMQERLRGVS EDENTQRYLF  240
VTEEDIKSLP SSQNETLIAI KAPYCTTLEV PDPDEVVDYP QRKYRIVLRS TTGPIDVYLL  300
SQFEEKFEIN GVNVGPNIPS RPDFNKHQST VVSNDRGKDL EMGIQDVYRP SDLSNSHDFA  360
GGITKIVPSD FESDADYWLL SDADVSITDM WRTEPGEVEW HNLETPKEDY CMTHVSPPPP  420
QTPPSNISEA PSASNPPVA

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
1cf7_A	1e-26	115	186	2	74	PROTEIN (TRANSCRIPTION FACTOR E2F-4)
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The binding of retinoblastoma-related proteins represses transactivation. Involved in the control of cell-cycle progression from G1 to S phase and from G2 to M phase. Stimulates cell proliferation and delays differentiation. Represses cell enlargement and endoreduplication in auxin-free conditions. {ECO:0000269\|PubMed:11669580, ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11862494, ECO:0000269\|PubMed:11891240, ECO:0000269\|PubMed:12913157, ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by light and by auxin. May be up-regulated by E2FA. {ECO:0000269\|PubMed:16055635, ECO:0000269\|PubMed:16514015, ECO:0000269\|PubMed:18424613}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016171961.1	0.0	transcription factor E2FB isoform X1
Refseq	XP_025673004.1	0.0	transcription factor E2FB isoform X1
Swissprot	Q9FV71	1e-139	E2FB_ARATH; Transcription factor E2FB
TrEMBL	A0A444Y7A8	0.0	A0A444Y7A8_ARAHY; Uncharacterized protein
STRING	AES88292	0.0	(Medicago truncatula)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT5G22220.2	1e-141	E2F transcription factor 1

Publications ? help Back to Top
Heyndrickx KS,Vandepoele K Systematic identification of functional plant modules through the integration of complementary data sources. Plant Physiol., 2012. 159(3): p. 884-901 [PMID:22589469] Wu M,Liu L,Hijazi H,Chan C A multi-layer inference approach to reconstruct condition-specific genes and their regulation. Bioinformatics, 2013. 29(12): p. 1541-52 [PMID:23610368] Kobayashi K, et al. Transcriptional repression by MYB3R proteins regulates plant organ growth. EMBO J., 2015. 34(15): p. 1992-2007 [PMID:26069325]