PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Ahy013511

Organism

Arachis hypogaea

Taxonomic ID

3818

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis

Family

E2F/DP

Protein Properties

Length: 358aa MW: 40516.1 Da PI: 8.2897

Description

E2F/DP family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
gnl\|UG\|Ahy#S59554016	PU_ref	Unigene	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	E2F_TDP	77	1.8e-24	12	77	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvsedvknkrRRiYDilNVLealnliekkekneirwkg 71 rk+ksL+ll+++flkl++k + + l+++a++L v +rRRiYDi+NVLe+++++++k+kn+++wkg Ahy013511 12 RKQKSLGLLCTNFLKLYNKDSIHLIGLDDAASRL---GV--ERRRIYDIVNVLESVGVLSRKAKNQYTWKG 77 79***************999********.....****************************98 PP
2	E2F_TDP	76.2	3.3e-24	146	226	1	71
E2F_TDP 1 rkeksLrlltqkflkllekseegivtlnevakeLvse.....dvknkrRRiYDilNVLealnliek.....kekneirwkg 71 r+eksL lltq+f+kl+ +s+ ++++l+e+ak L+ + +++k+RR+YDi+NVL+++nliek ++k+++rw g Ahy013511 146 RREKSLALLTQNFVKLFVCSNIEMISLDEAAKLLLGNahntsIMRTKVRRLYDIANVLSSMNLIEKthttdTRKPAFRWLG 226 689******************************999999***********************99*****87 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:1.10.10.10	6.2E-26	8	78	IPR011991	Winged helix-turn-helix DNA-binding domain
SuperFamily	SSF46785	1.87E-16	11	75	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.4E-28	12	77	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Pfam	PF02319	1.3E-20	13	77	IPR003316	E2F/DP family, winged-helix DNA-binding domain
Gene3D	G3DSA:1.10.10.10	1.9E-23	144	227	IPR011991	Winged helix-turn-helix DNA-binding domain
SMART	SM01372	1.8E-31	146	226	IPR003316	E2F/DP family, winged-helix DNA-binding domain
SuperFamily	SSF46785	4.99E-14	148	227	IPR011991	Winged helix-turn-helix DNA-binding domain
Pfam	PF02319	1.2E-19	148	226	IPR003316	E2F/DP family, winged-helix DNA-binding domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0005667	Cellular Component	transcription factor complex
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 358 aa Download sequence Send to blast
MDPSSRHYSY NRKQKSLGLL CTNFLKLYNK DSIHLIGLDD AASRLGVERR RIYDIVNVLE 60 SVGVLSRKAK NQYTWKGFAA IPGALQELKD EGLRENPYGF DGDNEIAKLS DDEDDEETMS 120 NPSNGSQNDK SNPNASLTKS LKPENRREKS LALLTQNFVK LFVCSNIEMI SLDEAAKLLL 180 GNAHNTSIMR TKVRRLYDIA NVLSSMNLIE KTHTTDTRKP AFRWLGLRGK PWSESGDSAL 240 NSNHSGESRK RMFGEDITNI SFKRNKVDLS MNAENSCKSY SKIQDQLEND DDSCWQAHTD 300 KGTVKQEGKQ NSKGYHFGPF APEYVSKNGG ASENTNVKQV HDWESLSNVY RPRYQNQD

Sequence ? help Back to Top

Protein Sequence Length: 358 aa Download sequence Send to blast

MDPSSRHYSY NRKQKSLGLL CTNFLKLYNK DSIHLIGLDD AASRLGVERR RIYDIVNVLE  60
SVGVLSRKAK NQYTWKGFAA IPGALQELKD EGLRENPYGF DGDNEIAKLS DDEDDEETMS  120
NPSNGSQNDK SNPNASLTKS LKPENRREKS LALLTQNFVK LFVCSNIEMI SLDEAAKLLL  180
GNAHNTSIMR TKVRRLYDIA NVLSSMNLIE KTHTTDTRKP AFRWLGLRGK PWSESGDSAL  240
NSNHSGESRK RMFGEDITNI SFKRNKVDLS MNAENSCKSY SKIQDQLEND DDSCWQAHTD  300
KGTVKQEGKQ NSKGYHFGPF APEYVSKNGG ASENTNVKQV HDWESLSNVY RPRYQNQD

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4yo2_A	2e-39	11	218	3	228	Transcription factor E2F8
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Inhibitor of E2F-dependent activation of gene expression. Binds specifically the E2 recognition site without interacting with DP proteins and prevents transcription activation by E2F/DP heterodimers. Controls the timing of endocycle onset and inhibits endoreduplication. {ECO:0000269\|PubMed:11786543, ECO:0000269\|PubMed:11867638, ECO:0000269\|PubMed:15649366, ECO:0000269\|PubMed:18787127}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_016203170.1	0.0	E2F transcription factor-like E2FE
Refseq	XP_025655266.1	0.0	E2F transcription factor-like E2FE
Swissprot	Q8LSZ4	1e-120	E2FE_ARATH; E2F transcription factor-like E2FE
TrEMBL	A0A444Z2R9	0.0	A0A444Z2R9_ARAHY; Uncharacterized protein
STRING	XP_007155383.1	1e-165	(Phaseolus vulgaris)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT3G48160.1	1e-123	DP-E2F-like 1

Publications ? help Back to Top
Chandran D, et al. Atypical E2F transcriptional repressor DEL1 acts at the intersection of plant growth and immunity by controlling the hormone salicylic acid. Cell Host Microbe, 2014. 15(4): p. 506-13 [PMID:24721578] Wang Z, et al. Del1 Knockout Mice Developed More Severe Osteoarthritis Associated with Increased Susceptibility of Chondrocytes to Apoptosis. PLoS ONE, 2016. 11(8): p. e0160684 [PMID:27505251] Heyman J,Polyn S,Eekhout T,De Veylder L Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1. Plant Physiol., 2017. 175(1): p. 303-313 [PMID:28698355]