PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aqcoe3G201200.1.p
Organism
Aquilegia coerulea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia
Family C2H2
Protein Properties Length: 453aa    MW: 52502.1 Da    PI: 9.3803
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aqcoe3G201200.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H216.72.1e-05375397123
                        EEETTTTEEESSHHHHHHHHHHT CS
            zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                        ++C +CgksF  k + ++H +++
  Aqcoe3G201200.1.p 375 FSCRKCGKSFAVKGDWRTHEKNC 397
                        89*****************9987 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.40.103.4E-18116192IPR013083Zinc finger, RING/FYVE/PHD-type
SuperFamilySSF579031.13E-16121191IPR011011Zinc finger, FYVE/PHD-type
PROSITE profilePS500169.561133182IPR019787Zinc finger, PHD-finger
SMARTSM002491.2E-7135180IPR001965Zinc finger, PHD-type
PfamPF006289.0E-9136181IPR019787Zinc finger, PHD-finger
PROSITE patternPS013590136179IPR019786Zinc finger, PHD-type, conserved site
SMARTSM004397.0E-14167300IPR001025Bromo adjacent homology (BAH) domain
PROSITE profilePS5103818.809182300IPR001025Bromo adjacent homology (BAH) domain
PfamPF014264.5E-12207297IPR001025Bromo adjacent homology (BAH) domain
SuperFamilySSF576675.77E-6361395No hitNo description
Gene3DG3DSA:3.30.160.601.0E-5362395IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501578.891375395IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0003682Molecular Functionchromatin binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 453 aa     Download sequence    Send to blast
MAETPKKPLQ STPKPKPKRS SNLTPKPSPS SVLSFFFAPE TPTPVRRSSR RIASNLNPET  60
PQKVPIQDKF IIKDAVTKTP KSVKTRVAAA EKLLQLKHLR YLDRFHQMFQ KQREEKDLKI  120
REDSSSDNED PEVEECRICF NVGKTIMIEC DDCLGGFHLK CLKPPLKQVP EGDWICGFCQ  180
ERKLGKKEKK LIRTAKEKLL SSDLWAVRIE SLWKEPNGTY WFRGRWYIIP EETAAGRQPH  240
NLRRELYRTN DFADVEMESV LRHCSVMNPK EFSKATNEGD DVFLCEYEYD VHWHSFKRLA  300
EIDNEKEMHM WGHGSQYRRG PDSLKGTQPT AMLKLPCYCC AHGCKNNINH PRAKPLKDFR  360
TLQTHYKRKH GAKPFSCRKC GKSFAVKGDW RTHEKNCGKL WYCICGSDFK HKRSLKDHVR  420
SFGDDHSPHP CHQSLEDQKE CITGSEDEIR SK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5hh7_A2e-8811830234230Origin of replication complex subunit 1B
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (By similarity). Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication (By similarity). H3K4me3 effector that regulates positively the transcription of a subset of genes (By similarity). Required for cell proliferation (PubMed:10996242). {ECO:0000250|UniProtKB:P54784, ECO:0000250|UniProtKB:Q710E8, ECO:0000303|PubMed:10996242}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Reduced expression upon sucrose depletion-mediated cell proliferation arrest, and accumulates after sucrose treatment (PubMed:10996242, PubMed:15939553). Induced by gamma irradiation (PubMed:25124817). {ECO:0000269|PubMed:10996242, ECO:0000269|PubMed:15939553, ECO:0000269|PubMed:25124817}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028062134.11e-111origin of replication complex subunit 1A-like
SwissprotQ5SMU77e-97ORC1_ORYSJ; Origin of replication complex subunit 1
TrEMBLA0A2G5DYJ71e-175A0A2G5DYJ7_AQUCA; Origin recognition complex subunit 1
STRINGAquca_014_00859.11e-176(Aquilegia coerulea)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G08290.14e-80WIP domain protein 3
Publications ? help Back to Top
  1. Kimura S, et al.
    Molecular cloning and characterization of a plant homologue of the origin recognition complex 1 (ORC1).
    Plant Sci., 2000. 158(1-2): p. 33-39
    [PMID:10996242]
  2. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  3. Mori Y, et al.
    Characterization of the origin recognition complex (ORC) from a higher plant, rice (Oryza sativa L.).
    Gene, 2005. 353(1): p. 23-30
    [PMID:15939553]
  4. Shultz RW,Tatineni VM,Hanley-Bowdoin L,Thompson WF
    Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice.
    Plant Physiol., 2007. 144(4): p. 1697-714
    [PMID:17556508]
  5. Hayashi G, et al.
    Unraveling low-level gamma radiation--responsive changes in expression of early and late genes in leaves of rice seedlings at Iitate Village, Fukushima.
    J. Hered., 2014 Sep-Oct. 105(5): p. 723-38
    [PMID:25124817]