PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

Aqcoe5G226900.2.p

Organism

Aquilegia coerulea

Taxonomic ID

218851

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia

Family

ARF

Protein Properties

Length: 939aa MW: 103845 Da PI: 5.8518

Description

ARF family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
Aqcoe5G226900.2.p	genome	JGI	View CDS

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	B3	73.9	1.9e-23	143	244	1	99
EEEE-..-HHHHTT-EE--HHH.HTT.......---..--SEEEEEETTS-EEEEEE..EEETTEEEE-TTHHHHHHHHT--TT-EEEEEE- CS B3 1 ffkvltpsdvlksgrlvlpkkfaeeh.......ggkkeesktltledesgrsWevkliyrkksgryvltkGWkeFvkangLkegDfvvFkld 85 f+k+lt sd++++g +++p++ ae+ +++ +++l+++d+++++W++++iyr++++r++lt+GW+ Fv +++L++gD v+F Aqcoe5G226900.2.p 143 FCKTLTASDTSTHGGFSVPRRAAEKLfpqldytV-QPP-TQELVVRDLHNNTWTFRHIYRGQPKRHLLTTGWSVFVGSKRLRAGDAVLFI-- 230 99*******************9999853.333.359**********************************************.. PP SSSEE..EEEEE-S CS B3 86 grsefelvvkvfrk 99 ++++ +l+++v+r+ Aqcoe5G226900.2.p 231 RDEKSQLLLGVRRA 244 45677789999997 PP
2	Auxin_resp	120.1	1.7e-39	269	352	1	83
Auxin_resp 1 aahaastksvFevvYnPrastseFvvkvekvekalk.vkvsvGmRfkmafetedsserrlsGtvvgvsdldpvrWpnSkWrsLk 83 aahaa+++s+F+++YnPra+++eFvv+++k++ka++ ++vs+GmRf m+fete+ss+rr++Gt+vg+sdldp+rWpnSkWr+L+ Aqcoe5G226900.2.p 269 AAHAAANRSPFTIFYNPRACPAEFVVPLAKYQKAVYgTQVSIGMRFGMMFETEESSKRRYMGTIVGISDLDPLRWPNSKWRNLQ 352 79********************************9*******************************************97 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
SuperFamily	SSF101936	6.54E-46	130	272	IPR015300	DNA-binding pseudobarrel domain
Gene3D	G3DSA:2.40.330.10	1.9E-40	135	257	IPR015300	DNA-binding pseudobarrel domain
CDD	cd10017	3.59E-21	142	243	No hit	No description
Pfam	PF02362	6.1E-21	143	244	IPR003340	B3 DNA binding domain
PROSITE profile	PS50863	12.943	143	245	IPR003340	B3 DNA binding domain
SMART	SM01019	5.5E-23	143	245	IPR003340	B3 DNA binding domain
Pfam	PF06507	2.1E-34	269	352	IPR010525	Auxin response factor
PROSITE profile	PS51745	24.61	843	927	IPR000270	PB1 domain
SuperFamily	SSF54277	9.81E-9	861	922	No hit	No description
Pfam	PF02309	1.4E-8	887	930	IPR033389	AUX/IAA domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0006355	Biological Process	regulation of transcription, DNA-templated
GO:0009733	Biological Process	response to auxin
GO:0009908	Biological Process	flower development
GO:0009942	Biological Process	longitudinal axis specification
GO:0010305	Biological Process	leaf vascular tissue pattern formation
GO:0048364	Biological Process	root development
GO:0048507	Biological Process	meristem development
GO:0005634	Cellular Component	nucleus
GO:0016020	Cellular Component	membrane
GO:0042802	Molecular Function	identical protein binding
GO:0044212	Molecular Function	transcription regulatory region DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 939 aa Download sequence Send to blast
MSAVEEKSKP VAVTPTLLEE MKIFKELQDQ SGTRKSIHSE LWHACAGPLV SLPQVGSLVY 60 YFPQGHSEQV AVSTKRPATS HIPNYPNLPS QLMCQVHNVT LHAEKDTDEI FAQMTLQPVN 120 SEKDVYPVPD FGLKSSKHPS EFFCKTLTAS DTSTHGGFSV PRRAAEKLFP QLDYTVQPPT 180 QELVVRDLHN NTWTFRHIYR GQPKRHLLTT GWSVFVGSKR LRAGDAVLFI RDEKSQLLLG 240 VRRANHQQTT LPSSVLSADS MHIGVLAAAA HAAANRSPFT IFYNPRACPA EFVVPLAKYQ 300 KAVYGTQVSI GMRFGMMFET EESSKRRYMG TIVGISDLDP LRWPNSKWRN LQVEWDESGG 360 GERQNRVSLW EIETPESLFV FSSLTSGFKR PLPPAFAGSE TEWGSLIRRP FIQIPESGNV 420 NIPCPPIPSL GSEQLIKMLM KPPIVSTSGA FSSSLPACVI KGNAMQDGAK LSHTMHQQKP 480 QSISLQSTSV VHQTPPQQCT DPSNPLDPKT ISQAPVPEKA HTRNSVENQL LRKTRTVKSE 540 ISFTDPSDRH RQMSEKCSED KLVGTFTNPK NLSNEPSFPN QGPLQLQNDQ QYVQHQLEPN 600 VVTVNPHHID ATQFEMNNLN SLFPYPSQFP SQYLDTDDWL QPPTCHSLLG NFKSPGSMSG 660 FEGCPAQDTS ITYPDYVNQI LPTYGSELGG PEMNYLGFFS QPDQLAQCPL QDSSTLQSVS 720 NSCGLRDASE ESKGHSGIYD ALNFEAINSG SAVVDPSVSS GVLNRFSSFG NVNFKNPEFL 780 VGGFSSSQDV QSQITTASLA DSQGFSLQEI QDNSGGTSSS NVDFDESSLF QQGPWKQVSP 840 PLRTYTKVQK VGSVGRSIDV TRFNGYEELR SAIGCMFGLE GVLDDPRGSE WRLVYVDYEN 900 DVLLVGDDPW EEFVTCVRCI RILSPSEVQQ MSEDGLLQ*

Sequence ? help Back to Top

Protein Sequence Length: 939 aa Download sequence Send to blast

MSAVEEKSKP VAVTPTLLEE MKIFKELQDQ SGTRKSIHSE LWHACAGPLV SLPQVGSLVY  60
YFPQGHSEQV AVSTKRPATS HIPNYPNLPS QLMCQVHNVT LHAEKDTDEI FAQMTLQPVN  120
SEKDVYPVPD FGLKSSKHPS EFFCKTLTAS DTSTHGGFSV PRRAAEKLFP QLDYTVQPPT  180
QELVVRDLHN NTWTFRHIYR GQPKRHLLTT GWSVFVGSKR LRAGDAVLFI RDEKSQLLLG  240
VRRANHQQTT LPSSVLSADS MHIGVLAAAA HAAANRSPFT IFYNPRACPA EFVVPLAKYQ  300
KAVYGTQVSI GMRFGMMFET EESSKRRYMG TIVGISDLDP LRWPNSKWRN LQVEWDESGG  360
GERQNRVSLW EIETPESLFV FSSLTSGFKR PLPPAFAGSE TEWGSLIRRP FIQIPESGNV  420
NIPCPPIPSL GSEQLIKMLM KPPIVSTSGA FSSSLPACVI KGNAMQDGAK LSHTMHQQKP  480
QSISLQSTSV VHQTPPQQCT DPSNPLDPKT ISQAPVPEKA HTRNSVENQL LRKTRTVKSE  540
ISFTDPSDRH RQMSEKCSED KLVGTFTNPK NLSNEPSFPN QGPLQLQNDQ QYVQHQLEPN  600
VVTVNPHHID ATQFEMNNLN SLFPYPSQFP SQYLDTDDWL QPPTCHSLLG NFKSPGSMSG  660
FEGCPAQDTS ITYPDYVNQI LPTYGSELGG PEMNYLGFFS QPDQLAQCPL QDSSTLQSVS  720
NSCGLRDASE ESKGHSGIYD ALNFEAINSG SAVVDPSVSS GVLNRFSSFG NVNFKNPEFL  780
VGGFSSSQDV QSQITTASLA DSQGFSLQEI QDNSGGTSSS NVDFDESSLF QQGPWKQVSP  840
PLRTYTKVQK VGSVGRSIDV TRFNGYEELR SAIGCMFGLE GVLDDPRGSE WRLVYVDYEN  900
DVLLVGDDPW EEFVTCVRCI RILSPSEVQQ MSEDGLLQ*

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
4ldu_A	0.0	16	377	32	392	Auxin response factor 5
Search in ModeBase

Functional Description ? help Back to Top
Source	Description
UniProt	Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity. {ECO:0000269\|PubMed:12036261, ECO:0000269\|PubMed:14973283, ECO:0000269\|PubMed:17553903}.

Binding Motif ? help Back to Top
Motif ID	Method	Source	Motif file
MP00153	DAP	Transfer from AT1G19850	Download

Regulation -- PlantRegMap ? help Back to Top
Source	Upstream Regulator	Target Gene
PlantRegMap	Retrieve	Retrieve

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_010271412.1	0.0	PREDICTED: auxin response factor 5-like
Refseq	XP_010271413.1	0.0	PREDICTED: auxin response factor 5-like
Swissprot	P93024	0.0	ARFE_ARATH; Auxin response factor 5
TrEMBL	A0A2G5EJT9	0.0	A0A2G5EJT9_AQUCA; Auxin response factor
STRING	Aquca_007_00393.1	0.0	(Aquilegia coerulea)

Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID	E-value	Description
AT1G19850.1	0.0	ARF family protein

Link Out ? help Back to Top
Phytozome	Aqcoe5G226900.2.p

Publications ? help Back to Top
Chen MK,Wilson RL,Palme K,Ditengou FA,Shpak ED ERECTA family genes regulate auxin transport in the shoot apical meristem and forming leaf primordia. Plant Physiol., 2013. 162(4): p. 1978-91 [PMID:23821653] Huang JB, et al. ROP3 GTPase contributes to polar auxin transport and auxin responses and is important for embryogenesis and seedling growth in Arabidopsis. Plant Cell, 2014. 26(9): p. 3501-18 [PMID:25217509] Qi J, et al. Auxin depletion from leaf primordia contributes to organ patterning. Proc. Natl. Acad. Sci. U.S.A., 2014. 111(52): p. 18769-74 [PMID:25512543] Crawford BC, et al. Plant development. Genetic control of distal stem cell fate within root and embryonic meristems. Science, 2015. 347(6222): p. 655-9 [PMID:25612610] Zhang Y, et al. Regulation of oncogene expression in T-DNA-transformed host plant cells. PLoS Pathog., 2015. 11(1): p. e1004620 [PMID:25615824] Robert HS, et al. Plant embryogenesis requires AUX/LAX-mediated auxin influx. Development, 2015. 142(4): p. 702-11 [PMID:25617434] Krogan NT,Berleth T The identification and characterization of specific ARF-Aux/IAA regulatory modules in plant growth and development. Plant Signal Behav, 2015. 10(4): p. e992748 [PMID:25830553] Ckurshumova W,Berleth T Overcoming recalcitrance - Auxin response factor functions in plant regeneration. Plant Signal Behav, 2015. 10(7): p. e993293 [PMID:26098229] Wendrich JR, et al. A set of domain-specific markers in the Arabidopsis embryo. Plant Reprod, 2015. 28(3-4): p. 153-60 [PMID:26216537] Wu MF, et al. Auxin-regulated chromatin switch directs acquisition of flower primordium founder fate. Elife, 2015. 4: p. e09269 [PMID:26460543] Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis. Plant Physiol., 2016. 170(1): p. 283-93 [PMID:26537561] Müller CJ, et al. PHABULOSA Mediates an Auxin Signaling Loop to Regulate Vascular Patterning in Arabidopsis. Plant Physiol., 2016. 170(2): p. 956-70 [PMID:26637548] Herud O,Weijers D,Lau S,Jürgens G Auxin responsiveness of the MONOPTEROS-BODENLOS module in primary root initiation critically depends on the nuclear import kinetics of the Aux/IAA inhibitor BODENLOS. Plant J., 2016. 85(2): p. 269-77 [PMID:26714008] Luo S, et al. Constitutive Expression of OsIAA9 Affects Starch Granules Accumulation and Root Gravitropic Response in Arabidopsis. Front Plant Sci, 2015. 6: p. 1156 [PMID:26734051] Yamaguchi N,Wu MF,Winter CM,Wagner D LEAFY and Polar Auxin Transport Coordinately Regulate Arabidopsis Flower Development. Plants (Basel), 2014. 3(2): p. 251-65 [PMID:27135503] Krogan NT,Marcos D,Weiner AI,Berleth T The auxin response factor MONOPTEROS controls meristem function and organogenesis in both the shoot and root through the direct regulation of PIN genes. New Phytol., 2016. 212(1): p. 42-50 [PMID:27441727] Fendrych M,Leung J,Friml J TIR1/AFB-Aux/IAA auxin perception mediates rapid cell wall acidification and growth of Arabidopsis hypocotyls. Elife, 2018. [PMID:27627746] Matthes M,Torres-Ruiz RA Boronic acid treatment phenocopies monopteros by affecting PIN1 membrane stability and polar auxin transport in Arabidopsis thaliana embryos. Development, 2016. 143(21): p. 4053-4062 [PMID:27697905] Bhatia N, et al. Auxin Acts through MONOPTEROS to Regulate Plant Cell Polarity and Pattern Phyllotaxis. Curr. Biol., 2016. 26(23): p. 3202-3208 [PMID:27818174] Wójcikowska B,Gaj MD Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis. Plant Cell Rep., 2017. 36(6): p. 843-858 [PMID:28255787] Möller BK, et al. Auxin response cell-autonomously controls ground tissue initiation in the early Arabidopsis embryo. Proc. Natl. Acad. Sci. U.S.A., 2017. 114(12): p. E2533-E2539 [PMID:28265057] Carey NS,Krogan NT The role of AUXIN RESPONSE FACTORs in the development and differential growth of inflorescence stems. Plant Signal Behav, 2017. 12(4): p. e1307492 [PMID:28340328] Guan C, et al. Spatial Auxin Signaling Controls Leaf Flattening in Arabidopsis. Curr. Biol., 2017. 27(19): p. 2940-2950.e4 [PMID:28943086] Gaillochet C, et al. Control of plant cell fate transitions by transcriptional and hormonal signals. Elife, 2018. [PMID:29058667] Zheng K, et al. Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis. Front Plant Sci, 2017. 8: p. 1813 [PMID:29114256] Liu Z, et al. ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis. Plant Cell Physiol., 2018. 59(1): p. 179-189 [PMID:29145642]