PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aqcoe6G259300.1.p
Organism
Aquilegia coerulea
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; stem eudicotyledons; Ranunculales; Ranunculaceae; Thalictroideae; Aquilegia
Family AP2
Protein Properties Length: 669aa    MW: 74090.7 Da    PI: 7.0404
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aqcoe6G259300.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP249.97.8e-16314373155
                AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                        s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  Aqcoe6G259300.1.p 314 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqtRKgRQVYLGGYDMEEKAARAYDLAALKYWG 373
                        78*******************988886678446*************************98 PP
2AP251.13.4e-16416467155
                AP2   1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                        s y+GV+++++ grW A+I  +     +k  +lg+fgt eeAa+a++ a+ k++g
  Aqcoe6G259300.1.p 416 SIYRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFGTQEEAAEAYDIAAIKFRG 467
                        57****************988532...5************************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008472.0E-12314373IPR001471AP2/ERF domain
SuperFamilySSF541714.64E-16314382IPR016177DNA-binding domain
CDDcd000183.33E-20314380No hitNo description
PROSITE profilePS5103218.795315381IPR001471AP2/ERF domain
SMARTSM003805.1E-25315387IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.1E-14315381IPR001471AP2/ERF domain
PRINTSPR003671.7E-6316327IPR001471AP2/ERF domain
SuperFamilySSF541711.37E-17416476IPR016177DNA-binding domain
PfamPF008475.8E-11416467IPR001471AP2/ERF domain
CDDcd000182.60E-25416475No hitNo description
PROSITE profilePS5103218.861417475IPR001471AP2/ERF domain
SMARTSM003809.4E-34417481IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.106.6E-18417475IPR001471AP2/ERF domain
PRINTSPR003671.7E-6457477IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 669 aa     Download sequence    Send to blast
MKSMNNNNNS SNNWLGVSLS PHLNIEVSSE SHHHPTQIPS SAVPRSFFLS SSHLNNSGIC  60
HGVDGENGGF YSHLSMMPLK SDGSLCIMEA LSRSQPEAIM PSSSPKLEDF LSGPTMGSHQ  120
YATNDREAMA LSLDSMYYHH NNSDTETNRQ SYLQHSYRQQ QQQQQHIQFQ QHPYFSGLSN  180
HEMYQAPLQD TKDNQLADCS SQLSPVAEDG TPNLRSWVTR QYSTNHTMEQ KMEGFLGDNG  240
GTGSVNAMGY GDLQSLSLSM SPGSQSSCVT APHQISPTGT ESMAMETKKR GSGKVGQKQP  300
VHRKSIDTFG QRTSQYRGVT RHRWTGRYEA HLWDNSCKKE GQTRKGRQVY LGGYDMEEKA  360
ARAYDLAALK YWGASTYINF SLENYQAELE EMKNMTRQEY VAHLRRKSSG FSRGASIYRG  420
VTRHHQHGRW QARIGRVAGN KDLYLGTFGT QEEAAEAYDI AAIKFRGTNA VTNFDMTRYD  480
VERIMASNTL LAGEHAKRNK EITASNEAID HHPSTQNSNG DVGLSEEHTV GGPDWKMVMY  540
QSSPHGPSDV AESIEQKPNG IGNYRNSSFS GALHDLIELH NMNSDQLVDD SATLGVHLSN  600
SSSLVTSVNS SREGSPDKNG MSMLFARPTS TSKFINPVTS MNSWISSAQL RPAGSMSHMP  660
MFAAWTDT*
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010248341.10.0PREDICTED: AP2-like ethylene-responsive transcription factor ANT
SwissprotQ389141e-167ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A2G5EMQ10.0A0A2G5EMQ1_AQUCA; Uncharacterized protein
STRINGAquca_006_00055.10.0(Aquilegia coerulea)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G37750.11e-131AP2 family protein
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]