PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Araha.0086s0004.1.p
Organism
Arabidopsis halleri
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family MYB
Protein Properties Length: 177aa    MW: 20669.4 Da    PI: 10.1698
Description MYB family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Araha.0086s0004.1.pgenomeJGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1Myb_DNA-binding42.51.5e-133074348
                         SS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHHHT CS
      Myb_DNA-binding  3 rWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqkyl 48
                          W++eEd++l + + ++G+++W+ Ia+++   ++  qc+ rw++yl
  Araha.0086s0004.1.p 30 TWSPEEDDILRKQISLFGTENWAIIASKFT-DKSTRQCRRRWYTYL 74
                         6****************************9.*************97 PP
2Myb_DNA-binding46.86.6e-1580123146
                          TSSS-HHHHHHHHHHHHHTTTT-HHHHHHHHTTTS-HHHHHHHHHH CS
      Myb_DNA-binding   1 rgrWTteEdellvdavkqlGggtWktIartmgkgRtlkqcksrwqk 46 
                          rg W++eEd ll +a +++G++ W+ Ia+ +  gRt++ +k+r+ +
  Araha.0086s0004.1.p  80 RGGWSPEEDTLLCEAQRLFGNR-WTEIAKVVS-GRTDNAVKNRFTT 123
                          789*******************.*********.**********976 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5129414.6282374IPR017930Myb domain
SuperFamilySSF466893.26E-2627121IPR009057Homeodomain-like
SMARTSM007171.1E-122776IPR001005SANT/Myb domain
CDDcd001671.87E-113074No hitNo description
Gene3DG3DSA:1.10.10.601.8E-203182IPR009057Homeodomain-like
PfamPF139211.4E-153191No hitNo description
PROSITE profilePS5129420.81275129IPR017930Myb domain
SMARTSM007178.4E-1579127IPR001005SANT/Myb domain
Gene3DG3DSA:1.10.10.609.3E-2083128IPR009057Homeodomain-like
CDDcd001674.12E-1083124No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 177 aa     Download sequence    Send to blast
MEETTKQNKK KKKILVNSDD SKKKERHIVT WSPEEDDILR KQISLFGTEN WAIIASKFTD  60
KSTRQCRRRW YTYLNSDFKR GGWSPEEDTL LCEAQRLFGN RWTEIAKVVS GRTDNAVKNR  120
FTTLCKKRAK HEAMAKENRI ACCVNSNNKR LLFPDDTQDS KIFAHSLGEF SFHHHT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1a5j_A3e-263112910108B-MYB
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds to DNA in promoters cis-regulatory element 5'-GGCGCGC-3' of cell cycle genes, including cyclins, cyclin-dependent kinases (CDKs), and components of the pre-replication complex (PubMed:20675570, PubMed:24687979). Binds to DNA in promoters cis-regulatory element 5'-AGCCG-3' of auxin regulated genes (e.g. PIN3 and PIN7) (PubMed:26578169). Together with FAMA and MYB124, ensures that stomata contain just two guard cells (GCs) by enforcing a single symmetric precursor cell division before stomatal maturity (PubMed:24571519). Represses the expression of the mitosis-inducing factors CDKB1-1 and CDKA-1, specifically required for the last guard mother cells (GMC) symmetric divisions in the stomatal pathway (PubMed:20675570, PubMed:24687979). Represses CYCA2-3 in newly formed guard cells (PubMed:21772250). Together with MYB88, regulates stomata spacing by restricting divisions late in the stomatal cell lineage thus limiting the number of GMC divisions (PubMed:16155180). In collaboration with CDKB1-1 and CDKB1-2, restrict the G1/S transition and chloroplast and nuclear number during stomatal formation, and normally maintain fate and developmental progression throughout the stomatal cell lineage (PubMed:24123248). Involved in sensing and/or transducing abiotic stress (e.g. drought and salt), probably via the positive regulation of NAC019 (PubMed:21105921). Regulates female reproduction being required for entry into megasporogenesis, probably via the regulation of cell cycle genes (PubMed:22915737). Plays a minor role in lateral roots (LRs) initiation (PubMed:26578065). Involved complementarily in establishing the gravitropic set-point angles of lateral roots by regulating the transcription of PIN3 and PIN7 in gravity-sensing cells of primary and lateral roots (PubMed:26578169). {ECO:0000269|PubMed:16155180, ECO:0000269|PubMed:20675570, ECO:0000269|PubMed:21105921, ECO:0000269|PubMed:21772250, ECO:0000269|PubMed:22915737, ECO:0000269|PubMed:24123248, ECO:0000269|PubMed:24571519, ECO:0000269|PubMed:24687979, ECO:0000269|PubMed:26578065, ECO:0000269|PubMed:26578169}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAraha.0086s0004.1.p
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1759940.0AF175994.2 Arabidopsis thaliana putative transcription factor (MYB88) mRNA, complete cds.
GenBankAK2265750.0AK226575.1 Arabidopsis thaliana mRNA for hypothetical protein, clone: RAFL07-13-I18.
GenBankAY5503050.0AY550305.1 Arabidopsis thaliana MYB transcription factor (at2g02825) mRNA, complete cds.
GenBankBT0263430.0BT026343.1 Arabidopsis thaliana At2g02820 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_001030957.11e-101myb domain protein 88
RefseqNP_001325364.11e-102myb domain protein 88
RefseqNP_565291.21e-101myb domain protein 88
SwissprotF4IRB41e-102MYB88_ARATH; Transcription factor MYB88
TrEMBLA0A178VPJ23e-99A0A178VPJ2_ARATH; MYB88
TrEMBLA0A1P8B2X71e-100A0A1P8B2X7_ARATH; Myb domain protein 88
STRINGAT2G02820.21e-100(Arabidopsis thaliana)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G02820.11e-104myb domain protein 88
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  3. Yang K, et al.
    Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.
    J. Exp. Bot., 2014. 65(9): p. 2449-61
    [PMID:24687979]
  4. Yang M
    The FOUR LIPS (FLP) and MYB88 genes conditionally suppress the production of nonstomatal epidermal cells in Arabidopsis cotyledons.
    Am. J. Bot., 2016. 103(9): p. 1559-66
    [PMID:27620181]
  5. Xu Z, et al.
    DGE-seq analysis of MUR3-related Arabidopsis mutants provides insight into how dysfunctional xyloglucan affects cell elongation.
    Plant Sci., 2017. 258: p. 156-169
    [PMID:28330559]
  6. Qu Y, et al.
    Peroxisomal CuAOζ and its product H2O2 regulate the distribution of auxin and IBA-dependent lateral root development in Arabidopsis.
    J. Exp. Bot., 2017. 68(17): p. 4851-4867
    [PMID:28992128]
  7. Xie Y, et al.
    An atypical R2R3 MYB transcription factor increases cold hardiness by CBF-dependent and CBF-independent pathways in apple.
    New Phytol., 2018. 218(1): p. 201-218
    [PMID:29266327]